| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is pcaB [H]
Identifier: 169627395
GI number: 169627395
Start: 290478
End: 291860
Strand: Direct
Name: pcaB [H]
Synonym: MAB_0290
Alternate gene names: 169627395
Gene position: 290478-291860 (Clockwise)
Preceding gene: 169627394
Following gene: 169627396
Centisome position: 5.73
GC content: 67.32
Gene sequence:
>1383_bases GTGAGCGGTTACGTGGACACCGGGCTGCTGTCTCCGGTCAGCGCGGGGACAGCAGCTGAGGCGGAACTGAGCGATGCGGC GTGGTTACAGGCCATGCTCGACGCAGAGGCCGCGCTGGCCGCTGCCCAGGCGGACATCGGTGTACTGCCGAGGGCGGCGG CAGATGTCATCGCCAGGGCGGCAGCCGGGCACGGCATCGACGTCCGTGCGGTGGCGCTGTCGGCGCGGGAGACGGCCAAC CCCGTCGTCGGGCTGATCAAAGAACTGTCCCGCGCCGTGGATGAGATCGAGCCGAGTGCAACAGATTACGTGCATCGCGG ATCAACCAGTCAGGATATTCTCGATACCGGCGCGATGATTGTGGCCAAGCGGGTGCTGGGGATCGTCGCGACGGATCTGG GGTACACGGCCGATGCCCTGGCAGAGCTGGCGGGCGCGCATAGCGGCACCGTGATGGCGGCCCGCACGCTGGCGATGCAG GCCGTACCGACGACGTTCGGGCTCAAGGCGTCCGGATGGCGTCAGCTGATCTTGGAGGCACGCGCGCGTGTGGTCGCGCT GGCGGATGCGCTGCCGGTATCTCTTGGTGGGGCGGCCGGAACTCTTGCCGGATACCTGGAATATGCGGGGCAGCACGGAG CCGATCCGGCAGTGTTCGTCGAGAAGCTGAACGCGGCATTCGCACACAGGACAGGGCTGGCCGCGTCCGGCCTGCCGTGG CATGCGCTGCGTACTCCGATAGCGGATATCGGCAGTACGACGGCATTTGTGACGGGTGCACTCGGGAAGTTCGCGGTCGA TGTGCTGACGTTGAGCCGCACCGAGATTGCCGAGGTGGCGGAGCCGGCTCCGCCGGGGCGTGGGGTGTCCTCGGCTATGC CACATAAGCGTAATCCGGTGTTGGCGACAATGATCCGGTCGGCAGCGCTGCAAGTCCCGTCCCTGAGCGTTGTGCTGACG CAGTCGTTGATGAGCGAGGACGAGCGGTCGGCCGGAGGCTGGCATGCGGAATGGCTGGTGCTGCGGGAGTGTTTGCGTCT CGCCGGGGGTGCGGCACAGACCGCGGTCGAGCTGAGCCGGGGGCTACAGGTGCGTGCCGACCGCATGGCGGAGAACCTTG CGCTGCTCGGCGGTCAGCCGTCGGCGGAGCGACTGGCGGCGGCGCTCGCGCCGCGGCTGGGCAAAGGCCCGGCAAAGGCC GTGGTCACCAACGTGGTGGATCAGGTGATTGCACGTGGCCTGAGTTTGCGCGAGGCGACTCGGGCGCGACCCGAGATCAT CGCGTGGTTGAGCGAGGCCGAGATCGATGAACTGCTGGACCCTGCCACCTACACAGGAGCAGCAGGTCAGCTTGTTGAGG AGGCCTTGACGCACCTCTCCTGA
Upstream 100 bases:
>100_bases TGGATTCGGTGACACTGGGTGACGCCGACGCTATTGCTCGTGCCGCCCTGGCGAGTGCGCCCACTGCGGCTGCGGATGTG GGCGATCACGGGGTGCTGGT
Downstream 100 bases:
>100_bases GCGAGTCACCTGCGCGAACTTTCGCTCGGGTTGATTCTTTGCGAACTGTTCGCGCGTAAGAGTCTTGACGGTGCCTTACC CCGCCCTTAGCGTTGCCACG
Product: 3-carboxymuconate cycloisomerase PcaB
Products: NA
Alternate protein names: 3-carboxymuconate lactonizing enzyme; CMLE [H]
Number of amino acids: Translated: 460; Mature: 459
Protein sequence:
>460_residues MSGYVDTGLLSPVSAGTAAEAELSDAAWLQAMLDAEAALAAAQADIGVLPRAAADVIARAAAGHGIDVRAVALSARETAN PVVGLIKELSRAVDEIEPSATDYVHRGSTSQDILDTGAMIVAKRVLGIVATDLGYTADALAELAGAHSGTVMAARTLAMQ AVPTTFGLKASGWRQLILEARARVVALADALPVSLGGAAGTLAGYLEYAGQHGADPAVFVEKLNAAFAHRTGLAASGLPW HALRTPIADIGSTTAFVTGALGKFAVDVLTLSRTEIAEVAEPAPPGRGVSSAMPHKRNPVLATMIRSAALQVPSLSVVLT QSLMSEDERSAGGWHAEWLVLRECLRLAGGAAQTAVELSRGLQVRADRMAENLALLGGQPSAERLAAALAPRLGKGPAKA VVTNVVDQVIARGLSLREATRARPEIIAWLSEAEIDELLDPATYTGAAGQLVEEALTHLS
Sequences:
>Translated_460_residues MSGYVDTGLLSPVSAGTAAEAELSDAAWLQAMLDAEAALAAAQADIGVLPRAAADVIARAAAGHGIDVRAVALSARETAN PVVGLIKELSRAVDEIEPSATDYVHRGSTSQDILDTGAMIVAKRVLGIVATDLGYTADALAELAGAHSGTVMAARTLAMQ AVPTTFGLKASGWRQLILEARARVVALADALPVSLGGAAGTLAGYLEYAGQHGADPAVFVEKLNAAFAHRTGLAASGLPW HALRTPIADIGSTTAFVTGALGKFAVDVLTLSRTEIAEVAEPAPPGRGVSSAMPHKRNPVLATMIRSAALQVPSLSVVLT QSLMSEDERSAGGWHAEWLVLRECLRLAGGAAQTAVELSRGLQVRADRMAENLALLGGQPSAERLAAALAPRLGKGPAKA VVTNVVDQVIARGLSLREATRARPEIIAWLSEAEIDELLDPATYTGAAGQLVEEALTHLS >Mature_459_residues SGYVDTGLLSPVSAGTAAEAELSDAAWLQAMLDAEAALAAAQADIGVLPRAAADVIARAAAGHGIDVRAVALSARETANP VVGLIKELSRAVDEIEPSATDYVHRGSTSQDILDTGAMIVAKRVLGIVATDLGYTADALAELAGAHSGTVMAARTLAMQA VPTTFGLKASGWRQLILEARARVVALADALPVSLGGAAGTLAGYLEYAGQHGADPAVFVEKLNAAFAHRTGLAASGLPWH ALRTPIADIGSTTAFVTGALGKFAVDVLTLSRTEIAEVAEPAPPGRGVSSAMPHKRNPVLATMIRSAALQVPSLSVVLTQ SLMSEDERSAGGWHAEWLVLRECLRLAGGAAQTAVELSRGLQVRADRMAENLALLGGQPSAERLAAALAPRLGKGPAKAV VTNVVDQVIARGLSLREATRARPEIIAWLSEAEIDELLDPATYTGAAGQLVEEALTHLS
Specific function: Catalyzes an anti cycloisomerization [H]
COG id: COG0015
COG function: function code F; Adenylosuccinate lyase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-II fumarase/aspartase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR019468 - InterPro: IPR003031 - InterPro: IPR000362 - InterPro: IPR020557 - InterPro: IPR008948 - InterPro: IPR022761 - InterPro: IPR012789 [H]
Pfam domain/function: PF10397 ADSL_C; PF00206 Lyase_1 [H]
EC number: =5.5.1.2 [H]
Molecular weight: Translated: 47323; Mature: 47192
Theoretical pI: Translated: 5.16; Mature: 5.16
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGYVDTGLLSPVSAGTAAEAELSDAAWLQAMLDAEAALAAAQADIGVLPRAAADVIARA CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH AAGHGIDVRAVALSARETANPVVGLIKELSRAVDEIEPSATDYVHRGSTSQDILDTGAMI HCCCCCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH VAKRVLGIVATDLGYTADALAELAGAHSGTVMAARTLAMQAVPTTFGLKASGWRQLILEA HHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH RARVVALADALPVSLGGAAGTLAGYLEYAGQHGADPAVFVEKLNAAFAHRTGLAASGLPW HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCH HALRTPIADIGSTTAFVTGALGKFAVDVLTLSRTEIAEVAEPAPPGRGVSSAMPHKRNPV HHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCH LATMIRSAALQVPSLSVVLTQSLMSEDERSAGGWHAEWLVLRECLRLAGGAAQTAVELSR HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH GLQVRADRMAENLALLGGQPSAERLAAALAPRLGKGPAKAVVTNVVDQVIARGLSLREAT CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH RARPEIIAWLSEAEIDELLDPATYTGAAGQLVEEALTHLS HCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC >Mature Secondary Structure SGYVDTGLLSPVSAGTAAEAELSDAAWLQAMLDAEAALAAAQADIGVLPRAAADVIARA CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH AAGHGIDVRAVALSARETANPVVGLIKELSRAVDEIEPSATDYVHRGSTSQDILDTGAMI HCCCCCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHH VAKRVLGIVATDLGYTADALAELAGAHSGTVMAARTLAMQAVPTTFGLKASGWRQLILEA HHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH RARVVALADALPVSLGGAAGTLAGYLEYAGQHGADPAVFVEKLNAAFAHRTGLAASGLPW HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCH HALRTPIADIGSTTAFVTGALGKFAVDVLTLSRTEIAEVAEPAPPGRGVSSAMPHKRNPV HHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCH LATMIRSAALQVPSLSVVLTQSLMSEDERSAGGWHAEWLVLRECLRLAGGAAQTAVELSR HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH GLQVRADRMAENLALLGGQPSAERLAAALAPRLGKGPAKAVVTNVVDQVIARGLSLREAT CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHH RARPEIIAWLSEAEIDELLDPATYTGAAGQLVEEALTHLS HCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8063101 [H]