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The map label for this gene is ccmG [H]

Identifier: 16767098

GI number: 16767098

Start: 4013361

End: 4013918

Strand: Reverse

Name: ccmG [H]

Synonym: STM3813

Alternate gene names: 16767098

Gene position: 4013918-4013361 (Counterclockwise)

Preceding gene: 16767099

Following gene: 16767097

Centisome position: 82.63

GC content: 62.19

Gene sequence:

>558_bases
ATGAAACGCAACGTACTGTTATTACCGCTGCTGATTTTTCTGCTGATTGCCGCGGCGCTGCTGTGGCAGCTGGCGCGCAA
CGCGCAGGGGGATGACCCGACGAATCTCGAATCGGCACTGACCGGAAAGCCGGTGCCGGCGTTCCGCCTGGAATCGCTGG
AGACGCCGGGTCAGTACTATCAGGCGGAGGTGCTGACGCAGGGGAAACCGGTGCTGCTTAACGTCTGGGCCACCTGGTGC
CCGACCTGCCGCGCCGAGCATCAGTACCTGAACCAGCTTTCTGCGCAGGGTATCCGGGTGGTGGGGCTGAACTATAAGGA
CGACCGGGCGAAGGCGGTGGCCTGGTTAAAGGAACTGGGCAACCCGTATGCGCTGAGTTTATCGGACAGCGACGGGATGC
TGGGGCTGGACCTGGGCGTGTACGGCGCGCCGGAAACCTTCCTCATCGACGGCAGGGGGATTATCCGCTACCGCCATGCG
GGCGATTTGAATGCCCGGGTATGGGAAAGTGAACTGAAACCGCTGTGGGACAGATACAGCCGGGAGGCGGCGCAATGA

Upstream 100 bases:

>100_bases
TCCGCTGGATATGGGCCGGGGGACTGCTGATGGCGCTGGGCGGGCTGCTGTGCCTGGCGGACCCGCGCTACCGCCGCCGT
AAACCATTGCCGGAGGCCGG

Downstream 100 bases:

>100_bases
GACTGTTACCGGGCATGGTGATGCTGATGCTGGCGCTGGTTATCTCCGGGTCAGCGCGGGCAACCACCGACGTGATGCCG
TTTAAAGATGAAGCGCAGGA

Product: heme lyase disulfide oxidoreductase

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWC
PTCRAEHQYLNQLSAQGIRVVGLNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHA
GDLNARVWESELKPLWDRYSREAAQ

Sequences:

>Translated_185_residues
MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWC
PTCRAEHQYLNQLSAQGIRVVGLNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHA
GDLNARVWESELKPLWDRYSREAAQ
>Mature_185_residues
MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWC
PTCRAEHQYLNQLSAQGIRVVGLNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHA
GDLNARVWESELKPLWDRYSREAAQ

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=185, Percent_Identity=87.027027027027, Blast_Score=341, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 20679; Mature: 20679

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCHHH
QAEVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVGLNYKDDRAKAVAWLKELG
HHHHHCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCC
NPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHAGDLNARVWESELKPLWDRYS
CCEEEEECCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
REAAQ
HHHCC
>Mature Secondary Structure
MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYY
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHCCCCCCHHH
QAEVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVGLNYKDDRAKAVAWLKELG
HHHHHCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCC
NPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHAGDLNARVWESELKPLWDRYS
CCEEEEECCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
REAAQ
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]