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The map label for this gene is xylB [H]

Identifier: 16766945

GI number: 16766945

Start: 3844913

End: 3846367

Strand: Reverse

Name: xylB [H]

Synonym: STM3660

Alternate gene names: 16766945

Gene position: 3846367-3844913 (Counterclockwise)

Preceding gene: 16766946

Following gene: 16766944

Centisome position: 79.19

GC content: 57.53

Gene sequence:

>1455_bases
ATGTATATCGGGATCGATCTTGGTACATCGGGTGTAAAAGCTATCCTGTTGAATGAGCAGGGCGATGTGCTGGCTACGCA
TACTGAAAAACTGACCGTATCGCGTCCGCATCCCTTATGGTCGGAACAGGAACCAGAGCAGTGGTGGCAGGCGACGGATC
GTGCGGTTAAAGGTTTAGGTCGGCAACAGTCGTTAAGTGGCGTCCGGGCGTTGGGCATCGCCGGACAAATGCATGGCGCG
ACATTGCTTGATAGCCGTCAGCAGGTTCTGCGACCAGCGATTTTATGGAATGACGGACGCTGTAGCGAAGAGTGCGCCTG
GCTGGAAAAACAGGTGCCGCAGTCGCGTGCGATAACCGGTAATCTGATGATGCCCGGTTTTACCGCGCCCAAATTAGTCT
GGGTGCAGCGCCACGAACCGGATATTTTCTACCAGATAGACAAGGTTCTGCTGCCGAAAGATTTTCTGCGGCTGCGAATG
ACAGGCGTCTTTGCCAGCGATATGTCGGATGCGGCGGGAACGATGTGGCTGGACGTGAAAAAGCGCGACTGGAGCGACGT
TATGCTCAACGCCTGTCATTTAACCCGACAGCAGATGCCAGCGTTATTTGAAGGTAGTGACATTACCGGAACGTTGCTGC
CGGAGGTGGCCAGCGCATGGGGAATGCCAGCAGTACCTGTGGTGGCGGGCGGCGGCGACAATGCGGCTGGCGCGGTCGGC
GTAGGAATGATCGATGCCGGACAGGCGATGCTCTCACTCGGAACATCGGGCGTCTATTTTGCCGTCAGCGACGGCTTTCT
GAGTAAACCGGAGAGCGCAGTACACAGTTTTTGCCATGCGCTGCCGGAACGCTGGCATTTAATGTCTGTGATGTTGAGCG
CCGCCTCTTGTCTGGACTGGGCGGCTAAACTCACCGGGCAGGAGAACGTCCCGGCGCTGATTGCCGCCGCACAGCAGGCG
GATGAGCATGCCGATTCGATCTGGTTTTTGCCGTACCTGTCCGGCGAGCGCACGCCGCATAATAATCCGCAGGCAAAAGG
CGTTTTCTTTGGTTTAACCCATCAGCATGGCCCGGCGGAACTGGCGCGGGCGGTACTGGAGGGCGTGGGATATGCTTTGG
CGGACGGTATGGATGTGGTTCACGCCTGCGGCGTCAAACCCGCCAGCGTGACGCTTATCGGCGGCGGGGCGCGCAGCGAA
TACTGGCGTCAGATGCTATCTGATATTAGCGGGCTACAGCTTGATTATCGTACTGGCGGCGATGTAGGGCCAGCGCTGGG
CGCGGCGCGTCTGGCGCAAATTGCGGTGAATAAACAGACCCCGCTCGCCGATGTATTGCCGCAGTTGCCGCTGGAGCAGG
CGCATTATCCTGATGCGCAGCGTCATGCGGTTTATCAACAACGTCGTGAAACCTTCCGTCGACTTTATCAGCAGCTGTTG
CCGTTGATGTCATAA

Upstream 100 bases:

>100_bases
ACCCTATCTACCGGGCGACTCCGCGTTAGCCCGGCCTGTAGTCGTGATTAGCCCGGTAAGCGTAGCGCTGCCGGGCGCTT
TCAGTAAAGGAACCCACACT

Downstream 100 bases:

>100_bases
GTCAGAATGCCTTTCAGTTTTGGCTGAAAGGCATTTCCCGTAAATATTAATTCTATTGAATTATATCGAAGTAAGTATGT
GTGTTTTCTGATTTTTATAT

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQEPEQWWQATDRAVKGLGRQQSLSGVRALGIAGQMHGA
TLLDSRQQVLRPAILWNDGRCSEECAWLEKQVPQSRAITGNLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRM
TGVFASDMSDAAGTMWLDVKKRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVASAWGMPAVPVVAGGGDNAAGAVG
VGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDWAAKLTGQENVPALIAAAQQA
DEHADSIWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGVKPASVTLIGGGARSE
YWRQMLSDISGLQLDYRTGGDVGPALGAARLAQIAVNKQTPLADVLPQLPLEQAHYPDAQRHAVYQQRRETFRRLYQQLL
PLMS

Sequences:

>Translated_484_residues
MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQEPEQWWQATDRAVKGLGRQQSLSGVRALGIAGQMHGA
TLLDSRQQVLRPAILWNDGRCSEECAWLEKQVPQSRAITGNLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRM
TGVFASDMSDAAGTMWLDVKKRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVASAWGMPAVPVVAGGGDNAAGAVG
VGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDWAAKLTGQENVPALIAAAQQA
DEHADSIWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGVKPASVTLIGGGARSE
YWRQMLSDISGLQLDYRTGGDVGPALGAARLAQIAVNKQTPLADVLPQLPLEQAHYPDAQRHAVYQQRRETFRRLYQQLL
PLMS
>Mature_484_residues
MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQEPEQWWQATDRAVKGLGRQQSLSGVRALGIAGQMHGA
TLLDSRQQVLRPAILWNDGRCSEECAWLEKQVPQSRAITGNLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRM
TGVFASDMSDAAGTMWLDVKKRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVASAWGMPAVPVVAGGGDNAAGAVG
VGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDWAAKLTGQENVPALIAAAQQA
DEHADSIWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGVKPASVTLIGGGARSE
YWRQMLSDISGLQLDYRTGGDVGPALGAARLAQIAVNKQTPLADVLPQLPLEQAHYPDAQRHAVYQQRRETFRRLYQQLL
PLMS

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=540, Percent_Identity=23.7037037037037, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI164663830, Length=563, Percent_Identity=22.5577264653641, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI18860918, Length=296, Percent_Identity=25.3378378378378, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789987, Length=484, Percent_Identity=85.9504132231405, Blast_Score=836, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=500, Percent_Identity=24.2, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790361, Length=478, Percent_Identity=22.5941422594142, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787789, Length=369, Percent_Identity=25.7452574525745, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789168, Length=415, Percent_Identity=23.855421686747, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17535599, Length=443, Percent_Identity=22.5733634311512, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17864214, Length=515, Percent_Identity=23.6893203883495, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24654573, Length=442, Percent_Identity=24.4343891402715, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356607, Length=320, Percent_Identity=24.6875, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52598; Mature: 52598

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQEPEQWWQATDRAVKGLG
CEEEEEECCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
RQQSLSGVRALGIAGQMHGATLLDSRQQVLRPAILWNDGRCSEECAWLEKQVPQSRAITG
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHEECCCCCCHHHHHHHHHCCCCCCCCC
NLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRMTGVFASDMSDAAGTMWLDVK
CEECCCCCCCEEEEEECCCCCHHEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEC
KRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVASAWGMPAVPVVAGGGDNAAGAVG
CCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEE
VGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDW
ECCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKLTGQENVPALIAAAQQADEHADSIWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAE
HHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGVKPASVTLIGGGARSEYWRQMLSDISGLQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCC
DVGPALGAARLAQIAVNKQTPLADVLPQLPLEQAHYPDAQRHAVYQQRRETFRRLYQQLL
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PLMS
HCCC
>Mature Secondary Structure
MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQEPEQWWQATDRAVKGLG
CEEEEEECCCCEEEEEECCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCC
RQQSLSGVRALGIAGQMHGATLLDSRQQVLRPAILWNDGRCSEECAWLEKQVPQSRAITG
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHEECCCCCCHHHHHHHHHCCCCCCCCC
NLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRMTGVFASDMSDAAGTMWLDVK
CEECCCCCCCEEEEEECCCCCHHEEHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEC
KRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVASAWGMPAVPVVAGGGDNAAGAVG
CCCHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCEEE
VGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHSFCHALPERWHLMSVMLSAASCLDW
ECCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAKLTGQENVPALIAAAQQADEHADSIWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPAE
HHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHH
LARAVLEGVGYALADGMDVVHACGVKPASVTLIGGGARSEYWRQMLSDISGLQLDYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCC
DVGPALGAARLAQIAVNKQTPLADVLPQLPLEQAHYPDAQRHAVYQQRRETFRRLYQQLL
CCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
PLMS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]