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The map label for this gene is spaR

Identifier: 16766194

GI number: 16766194

Start: 3032590

End: 3033381

Strand: Reverse

Name: spaR

Synonym: STM2888

Alternate gene names: 16766194

Gene position: 3033381-3032590 (Counterclockwise)

Preceding gene: 16766195

Following gene: 16766193

Centisome position: 62.45

GC content: 49.37

Gene sequence:

>792_bases
ATGTTTTACGCGTTGTACTTTGAAATTCATCACCTGGTTGCGTCTGCGGCGCTAGGGTTTGCTCGCGTGGCGCCGATTTT
TTTCTTCCTGCCGTTTTTGAATAGCGGGGTATTAAGCGGTGCGCCGAGAAACGCCATTATCATCCTGGTGGCATTGGGAG
TATGGCCGCATGCATTGAACGAGGCGCCGCCGTTTTTATCGGTGGCGATGATCCCGTTAGTTCTGCAAGAAGCGGCGGTA
GGCGTCATGCTGGGCTGTCTGCTGTCATGGCCTTTTTGGGTTATGCATGCGCTGGGTTGTATTATCGATAACCAGCGAGG
GGCAACGCTAAGTAGTAGTATCGATCCGGCAAACGGTATTGATACCTCGGAAATGGCTAATTTCCTGAATATGTTTGCCG
CTGTCGTTTATTTACAAAACGGCGGTCTGGTCACGATGGTTGACGTGTTAAATAAAAGCTATCAGCTATGCGATCCGATG
AACGAGTGCACGCCTTCATTACCGCCGCTATTAACGTTTATTAATCAGGTGGCTCAAAACGCCTTGGTTCTGGCCAGTCC
GGTGGTATTAGTGCTGTTGCTGTCAGAAGTATTCCTGGGTTTATTGTCGCGCTTTGCTCCGCAAATGAACGCTTTTGCGA
TTTCACTGACGGTAAAAAGCGGTATTGCCGTTTTAATTATGCTGCTTTATTTCTCTCCGGTACTACCGGACAATGTACTG
CGACTCTCTTTCCAGGCCACAGGGTTAAGCAGTTGGTTTTACGAGCGAGGGGCGACGCATGTCCTCGAATAA

Upstream 100 bases:

>100_bases
CGTGTGTTTATGCTTGTTTTTACTGTCTGGCTGGTATGGCGAAGTTTTACTCTCTTACGGGCGTCAGGTGATATTCCTGG
CGTTGGCTAAGGGGTAAAAA

Downstream 100 bases:

>100_bases
AACAGAAAAACCGACTAAAAAACGGCTGGAAGACTCCGCTAAAAAAGGCCAGTCATTTAAAAGTAAAGATCTCATTATCG
CCTGCCTGACGCTGGGAGGA

Product: needle complex export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVL
RLSFQATGLSSWFYERGATHVLE

Sequences:

>Translated_263_residues
MFYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVL
RLSFQATGLSSWFYERGATHVLE
>Mature_263_residues
MFYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVL
RLSFQATGLSSWFYERGATHVLE

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPAR_SALTY (P40701)

Other databases:

- EMBL:   X73525
- EMBL:   AE006468
- PIR:   S37309
- RefSeq:   NP_461809.1
- GeneID:   1254411
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2888
- NMPDR:   fig|99287.1.peg.2785
- HOGENOM:   HBG474088
- OMA:   YTAFISS
- ProtClustDB:   PRK15332
- BioCyc:   STYP99287:STM2888-MONOMER
- GO:   GO:0009405
- InterPro:   IPR002010
- InterPro:   IPR006304
- PRINTS:   PR00953
- TIGRFAMs:   TIGR01401

Pfam domain/function: PF01311 Bac_export_1

EC number: NA

Molecular weight: Translated: 28487; Mature: 28487

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10520cc0)-; HASH(0x1106ad10)-; HASH(0x10d8279c)-; HASH(0x105ef034)-; HASH(0xca6ed8c)-; HASH(0x106ba368)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHCCHHHHC
EAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPMNECTPSLPPLLTFINQVAQN
CHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHCCCHHHCCCCCCHHHHHHHHHHHH
ALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHE
RLSFQATGLSSWFYERGATHVLE
EEEEECCCHHHHHHHCCCHHCCH
>Mature Secondary Structure
MFYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHCCHHHHC
EAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPMNECTPSLPPLLTFINQVAQN
CHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHCCCHHHCCCCCCHHHHHHHHHHHH
ALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHE
RLSFQATGLSSWFYERGATHVLE
EEEEECCCHHHHHHHCCCHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609