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The map label for this gene is hxlB [H]

Identifier: 16766068

GI number: 16766068

Start: 2894344

End: 2894907

Strand: Reverse

Name: hxlB [H]

Synonym: STM2756

Alternate gene names: 16766068

Gene position: 2894907-2894344 (Counterclockwise)

Preceding gene: 16766069

Following gene: 16766067

Centisome position: 59.6

GC content: 57.8

Gene sequence:

>564_bases
ATGGAAACGCAATCTGTTGCAGGCGTTGCCTGTAGCGACCTGAATCAGGCGATGTCGCGGATTGATGGCGCTGCGCTGGC
GCGTCTGGAGCAGGCCATTGCTGACGCGAAAGCGGTATTTGTTTTTGGCGCAGGGCGTTCGCTGTTGATGCTGAAAGCTT
TTGCGATGCGCCTGATGCATATCGGCCTGAAGGTGCATGTTGTCGGCGATGTGGTCACGCCTGCGCTGCAAAAAGGCGAC
CTGCTGTTACTGGCGAGTGCATCGGGTGAAACGGCTTCGCTGGTGAATGTGGCAACGAAAGCGAAGCAACTGGGTGGCAC
TGTGGCCTTGCTGACCATTTTCCCCGAGTCCACGCTGGGGAAACTGGCGGGGGTGGCGGTCAGGATCCCGGCTTATTCCG
ACAAACTGCCGGATGGACCCGAGAATGTGAAAGGTATTCTGCCCGGCGGCAGCTTGTTTGAAGAGGCGGTCATGGTGCTG
GGTGACGCCATGATTGTGAATCTGGCGCAGTCGACGGGATATCGCTTAACCAAAGGCTTTGCGCTGCACGCCAACCTCGA
ATAG

Upstream 100 bases:

>100_bases
GTTTTCATTTTCTGGGGCATGTCGATAACTATGTCCGGGAAATCATGGGGATGCTCCAGTATGAGGATGATTTATTCCCG
CTCTGTCAGGAGGACGCATG

Downstream 100 bases:

>100_bases
TCATTCGACACAAGGAAACCAACATGAAATTACAGCTTGCCCTGGACGAGTTAACCCTGCCTGAAGCGATGGTATTTATG
GATAAGGTGGTTGATGACGT

Product: sugar phosphate aminotransferase

Products: NA

Alternate protein names: 6-phospho-3-hexuloisomerase; PHI [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
METQSVAGVACSDLNQAMSRIDGAALARLEQAIADAKAVFVFGAGRSLLMLKAFAMRLMHIGLKVHVVGDVVTPALQKGD
LLLLASASGETASLVNVATKAKQLGGTVALLTIFPESTLGKLAGVAVRIPAYSDKLPDGPENVKGILPGGSLFEEAVMVL
GDAMIVNLAQSTGYRLTKGFALHANLE

Sequences:

>Translated_187_residues
METQSVAGVACSDLNQAMSRIDGAALARLEQAIADAKAVFVFGAGRSLLMLKAFAMRLMHIGLKVHVVGDVVTPALQKGD
LLLLASASGETASLVNVATKAKQLGGTVALLTIFPESTLGKLAGVAVRIPAYSDKLPDGPENVKGILPGGSLFEEAVMVL
GDAMIVNLAQSTGYRLTKGFALHANLE
>Mature_187_residues
METQSVAGVACSDLNQAMSRIDGAALARLEQAIADAKAVFVFGAGRSLLMLKAFAMRLMHIGLKVHVVGDVVTPALQKGD
LLLLASASGETASLVNVATKAKQLGGTVALLTIFPESTLGKLAGVAVRIPAYSDKLPDGPENVKGILPGGSLFEEAVMVL
GDAMIVNLAQSTGYRLTKGFALHANLE

Specific function: Catalyzes the isomerization between 3-hexulose 6- phosphate and fructose 6-phosphate. Together with hxlA, may act as a formaldehyde detoxification system [H]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017552
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.27 [H]

Molecular weight: Translated: 19329; Mature: 19329

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQSVAGVACSDLNQAMSRIDGAALARLEQAIADAKAVFVFGAGRSLLMLKAFAMRLMH
CCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHH
IGLKVHVVGDVVTPALQKGDLLLLASASGETASLVNVATKAKQLGGTVALLTIFPESTLG
CCEEEEEECCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHH
KLAGVAVRIPAYSDKLPDGPENVKGILPGGSLFEEAVMVLGDAMIVNLAQSTGYRLTKGF
HHCCEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEHHCCCCEEECCE
ALHANLE
EEEECCC
>Mature Secondary Structure
METQSVAGVACSDLNQAMSRIDGAALARLEQAIADAKAVFVFGAGRSLLMLKAFAMRLMH
CCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHH
IGLKVHVVGDVVTPALQKGDLLLLASASGETASLVNVATKAKQLGGTVALLTIFPESTLG
CCEEEEEECCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHH
KLAGVAVRIPAYSDKLPDGPENVKGILPGGSLFEEAVMVLGDAMIVNLAQSTGYRLTKGF
HHCCEEEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHEEEHHCCCCEEECCE
ALHANLE
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 7921238 [H]