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The map label for this gene is allR

Identifier: 16763896

GI number: 16763896

Start: 576564

End: 577382

Strand: Direct

Name: allR

Synonym: STM0516

Alternate gene names: 16763896

Gene position: 576564-577382 (Clockwise)

Preceding gene: 16763895

Following gene: 16763897

Centisome position: 11.87

GC content: 54.95

Gene sequence:

>819_bases
ATGACGGAAGTAAGACGACGCGGCAGGCCAGGACAGGCAGAGCCGACTGCGCAGAAAGGCGCTCAGGCGCTGGAGAGGGG
CATAGCGATATTGCAATATCTCGAAAGAAGCGGCGGCAGTTCATCAGTTAGCGATATTTCCGGCAGCCTGGATTTACCGC
TTTCTACGACGTTTCGCCTGTTAAAGGTACTGCAAGCGGCTGATTTTGTGTACCAGGATAGCCAGCTTGGCTGGTGGCAT
ATTGGTTTAGGCGTATTTAATGTGGGCTCTGCGTATATTCATAATCGCGATGTCCTCTCGGTAGCCGGGCCCTTTATGCA
CCGACTTATGCTGCTTTCTGGCGAGACGGTCAACGTAGCGATTCGCAACGGTAATGAAGCGGTGTTAATCGGTCAAAAGG
AGTGCAAATCGATGGTCAGAATGTGCGCGCCCTTAGGGAGTCGTCTGCCGTTACATGCTTCCGGCGCCGGAAAAGCGCTG
CTTTACCCGCTCACCGAAGAAGAGCTGGTGGGGATCGTCGTCAATACCGGTTTGCGGCGGTTTACGCCGACCACTCTGGT
GGATTTACCTATCCTGCTTAAAAATCTGGAGCAGGCGCGTGAACAGGGCTACACCGTCGACCAGGAAGAACATGTTGTCG
GGCTGAATTGTATCGCCTCCGCTATCTATGACGATGCGGGCAGCGTGGTCGCCGCTATCTCGATATCGGGACCGGCTTCC
CGGCTGACGGAAGATCGCTTTATCAGCCAGGGTGAACTGGTACGGGATACCGCGAAAGACATCAGTACGGCGCTTGGGCT
AAAACCCCCTGTAGCCTGA

Upstream 100 bases:

>100_bases
ACATGAACTCTGTTTTGCGTGACGCTATTGGCCTTCTTGCATAAGATGAACATATTGTTCATTGTTTATGCTCATATTTT
GGGCCGGAGTTAACGTAAAT

Downstream 100 bases:

>100_bases
GCCGCATCCCGCTCGCTGGAGCGGGACTTTTTTAAAATTTTTAAAAGTTGGAAACTTTTTCCAATAAAAAGAGGTAGCAA
TAAAATGGCAAAAATGAGAG

Product: DNA-binding transcriptional repressor AllR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWH
IGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLEQAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
RLTEDRFISQGELVRDTAKDISTALGLKPPVA

Sequences:

>Translated_272_residues
MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWH
IGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLEQAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
RLTEDRFISQGELVRDTAKDISTALGLKPPVA
>Mature_271_residues
TEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHI
GLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALL
YPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLEQAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPASR
LTEDRFISQGELVRDTAKDISTALGLKPPVA

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain

Homologues:

Organism=Escherichia coli, GI1786715, Length=268, Percent_Identity=91.044776119403, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI87082359, Length=264, Percent_Identity=42.4242424242424, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=31.0204081632653, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788131, Length=241, Percent_Identity=30.7053941908714, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789999, Length=252, Percent_Identity=28.968253968254, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790752, Length=252, Percent_Identity=26.984126984127, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=27.710843373494, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALLR_SALCH (Q57S48)

Other databases:

- EMBL:   AE017220
- RefSeq:   YP_215544.1
- HSSP:   P16528
- ProteinModelPortal:   Q57S48
- SMR:   Q57S48
- PRIDE:   Q57S48
- GeneID:   3332981
- GenomeReviews:   AE017220_GR
- KEGG:   sec:SC0557
- HOGENOM:   HBG739407
- OMA:   DDEENEY
- ProtClustDB:   PRK10163
- BioCyc:   SENT321314:SCH_0557-MONOMER
- GO:   GO:0006350
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00346

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR

EC number: NA

Molecular weight: Translated: 29220; Mature: 29089

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51077 HTH_ICLR; PS51078 ICLR_ED

Important sites: BINDING 207-207 BINDING 217-217

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHH
LKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVA
HHHHHHHHHHEECCCCCEEEECCHHHHCCCHHEECCCHHHHHHHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALLYPLTEEELVGIVVNTGLRR
EECCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCHHHHEEHHHHCCCHH
FTPTTLVDLPILLKNLEQAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEEECCCHH
RLTEDRFISQGELVRDTAKDISTALGLKPPVA
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHH
LKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVA
HHHHHHHHHHEECCCCCEEEECCHHHHCCCHHEECCCHHHHHHHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALLYPLTEEELVGIVVNTGLRR
EECCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCHHHHEEHHHHCCCHH
FTPTTLVDLPILLKNLEQAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEEECCCHH
RLTEDRFISQGELVRDTAKDISTALGLKPPVA
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA