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The map label for this gene is glmU [H]

Identifier: 167626193

GI number: 167626193

Start: 5198867

End: 5200231

Strand: Reverse

Name: glmU [H]

Synonym: Shal_4288

Alternate gene names: 167626193

Gene position: 5200231-5198867 (Counterclockwise)

Preceding gene: 167626194

Following gene: 167626192

Centisome position: 99.49

GC content: 47.84

Gene sequence:

>1365_bases
ATGGCATTGAATGTAGTAATTTTGGCCGCAGGCAAGGGAACCCGCATGCGCTCAGATCTTCCAAAAGTTCTTCACCCTAT
CGCTCATAAGAGCATGGTTCAGCATGTAATTGATACTGCACATCAAGTGGGCAGTGATGCTATCCAGCTGGTTTATGGCT
ATGGCGCCGATAAGCTACAAGCAAAACTGGGTGAGCAGCAGCTAAATTGGGTACTACAAGCTGAGCAATTAGGCACTGGG
CATGCGGTAGCGCAGGCTAATGATAATATTAGTGATGACGATACGGTGCTGATTCTTTATGGTGATGTGCCACTGATCCA
AGCTTCTACACTTGAAGCTTTACTTGCTGCTCGAGAAGATAATGGTCTAGCTATTTTGACTGTTAACCTGCCTAATCCGA
CAGGCTATGGCCGTATAGTGCGAGAGGATGGAAACGTCGTTGGTATTGTTGAGCAGAAAGATGCCAATGCCGAGCAACTA
GCTATCAGTGAGATCAATACTGGCATTATGGCGACGCCGGGTAAGCAACTAAAGGCTTGGTTAGGTCAATTATCATCAGA
CAATGCTCAAGGTGAATACTACCTTACTGATATCGTTGCCATGGCACACAAAGATGGTGTTGCCATTACTACTGCGCAGC
CTGAATCCGCTGTGGAAGTTGAAGGTGCAAATAACCGCGTACAACTGGCGCAGCTTGAGCGTGCTTACCAAGCGCGAGCA
GCTGAAAAGCTGATGCTTGAAGGGGCCAATCTGCGCGATCCTGCTCGTATCGACATTCGCGGTGACGTCACCGTGGGCAT
GGATGTGATGATCGACATTAACGTGGTTATCGAGGGTAAGGTGACTATCGGTAATAATGTCACTATTGGCGCGGGTGCCA
TCCTTATCGATTGCGAGATTAGCGACAACGCAGTGATAAAACCTTACTCGATTATCGAGAGTGCAAAGGTTGGTGTTGAT
GCCAGCGCAGGTCCTTTTGCACGCTTGCGTCCTGGCGCAGAGCTTAAACAAGACGCCCATATTGGCAACTTCGTTGAAAT
GAAAAAAGCGGTATTAGGTAAAGGCTCTAAAGCGGGACATTTGGCCTATATTGGCGATGCGACTATCGGTGCTGGGGTAA
ATATCGGTGCAGGTACTATTACCTGTAACTATGATGGTGCCAATAAGTTCCAAACGATTATTGAAGACAATGTATTTGTC
GGCAGTGATACCCAGTTGGTTGCACCTGTGACTATTGGTGAAGGTGCTACTTTGGGGGCGGGTTCTACCATAACTAAAGA
TGTTGCGGCTGGTGAGTTGGTTATCACCCGCGTTAAACAGCGTCATTTGACTGGCTGGGCGCGACCCGTTAAGCAGAAAA
AGTAA

Upstream 100 bases:

>100_bases
AAGTCGAGTCGCTTTTAATAACTGTATCGCTTAAAATCGGCTGTCTAATAAAGACCTCATTTTTCTAACATCAGTTAAAG
CATTAGCTCAAGGATAATCC

Downstream 100 bases:

>100_bases
AGATTAGTTATTTCAAAAAAGCGACTCTAGTGTCGCTTTTTTGCTTTTTATTTAATCGATTATTTAGGCGTTCAGTTTAT
TGGAATAACGCCAATACCGA

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHQVGSDAIQLVYGYGADKLQAKLGEQQLNWVLQAEQLGTG
HAVAQANDNISDDDTVLILYGDVPLIQASTLEALLAAREDNGLAILTVNLPNPTGYGRIVREDGNVVGIVEQKDANAEQL
AISEINTGIMATPGKQLKAWLGQLSSDNAQGEYYLTDIVAMAHKDGVAITTAQPESAVEVEGANNRVQLAQLERAYQARA
AEKLMLEGANLRDPARIDIRGDVTVGMDVMIDINVVIEGKVTIGNNVTIGAGAILIDCEISDNAVIKPYSIIESAKVGVD
ASAGPFARLRPGAELKQDAHIGNFVEMKKAVLGKGSKAGHLAYIGDATIGAGVNIGAGTITCNYDGANKFQTIIEDNVFV
GSDTQLVAPVTIGEGATLGAGSTITKDVAAGELVITRVKQRHLTGWARPVKQKK

Sequences:

>Translated_454_residues
MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHQVGSDAIQLVYGYGADKLQAKLGEQQLNWVLQAEQLGTG
HAVAQANDNISDDDTVLILYGDVPLIQASTLEALLAAREDNGLAILTVNLPNPTGYGRIVREDGNVVGIVEQKDANAEQL
AISEINTGIMATPGKQLKAWLGQLSSDNAQGEYYLTDIVAMAHKDGVAITTAQPESAVEVEGANNRVQLAQLERAYQARA
AEKLMLEGANLRDPARIDIRGDVTVGMDVMIDINVVIEGKVTIGNNVTIGAGAILIDCEISDNAVIKPYSIIESAKVGVD
ASAGPFARLRPGAELKQDAHIGNFVEMKKAVLGKGSKAGHLAYIGDATIGAGVNIGAGTITCNYDGANKFQTIIEDNVFV
GSDTQLVAPVTIGEGATLGAGSTITKDVAAGELVITRVKQRHLTGWARPVKQKK
>Mature_453_residues
ALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHQVGSDAIQLVYGYGADKLQAKLGEQQLNWVLQAEQLGTGH
AVAQANDNISDDDTVLILYGDVPLIQASTLEALLAAREDNGLAILTVNLPNPTGYGRIVREDGNVVGIVEQKDANAEQLA
ISEINTGIMATPGKQLKAWLGQLSSDNAQGEYYLTDIVAMAHKDGVAITTAQPESAVEVEGANNRVQLAQLERAYQARAA
EKLMLEGANLRDPARIDIRGDVTVGMDVMIDINVVIEGKVTIGNNVTIGAGAILIDCEISDNAVIKPYSIIESAKVGVDA
SAGPFARLRPGAELKQDAHIGNFVEMKKAVLGKGSKAGHLAYIGDATIGAGVNIGAGTITCNYDGANKFQTIIEDNVFVG
SDTQLVAPVTIGEGATLGAGSTITKDVAAGELVITRVKQRHLTGWARPVKQKK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=452, Percent_Identity=60.6194690265487, Blast_Score=566, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47853; Mature: 47722

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHQVGSDAIQLVYGYGADKLQ
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHH
AKLGEQQLNWVLQAEQLGTGHAVAQANDNISDDDTVLILYGDVPLIQASTLEALLAARED
HHHCHHHHHEEEEHHHCCCCCEEEECCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHCCC
NGLAILTVNLPNPTGYGRIVREDGNVVGIVEQKDANAEQLAISEINTGIMATPGKQLKAW
CCEEEEEEECCCCCCCCEEEEECCCEEEEEECCCCCHHHEEHHHCCCCEEECCCHHHHHH
LGQLSSDNAQGEYYLTDIVAMAHKDGVAITTAQPESAVEVEGANNRVQLAQLERAYQARA
HHHCCCCCCCCCEEHEEHHHHHCCCCEEEEECCCCCEEEEECCCCEEEHHHHHHHHHHHH
AEKLMLEGANLRDPARIDIRGDVTVGMDVMIDINVVIEGKVTIGNNVTIGAGAILIDCEI
HHHHHHCCCCCCCCEEEEEECCEEECEEEEEEEEEEEEEEEEECCEEEEECCEEEEEEEE
SDNAVIKPYSIIESAKVGVDASAGPFARLRPGAELKQDAHIGNFVEMKKAVLGKGSKAGH
CCCCEECCHHHHHHHHCCCCCCCCCCHHCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCE
LAYIGDATIGAGVNIGAGTITCNYDGANKFQTIIEDNVFVGSDTQLVAPVTIGEGATLGA
EEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEECCCCEEEEEEEECCCCCCCC
GSTITKDVAAGELVITRVKQRHLTGWARPVKQKK
CCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ALNVVILAAGKGTRMRSDLPKVLHPIAHKSMVQHVIDTAHQVGSDAIQLVYGYGADKLQ
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHH
AKLGEQQLNWVLQAEQLGTGHAVAQANDNISDDDTVLILYGDVPLIQASTLEALLAARED
HHHCHHHHHEEEEHHHCCCCCEEEECCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHCCC
NGLAILTVNLPNPTGYGRIVREDGNVVGIVEQKDANAEQLAISEINTGIMATPGKQLKAW
CCEEEEEEECCCCCCCCEEEEECCCEEEEEECCCCCHHHEEHHHCCCCEEECCCHHHHHH
LGQLSSDNAQGEYYLTDIVAMAHKDGVAITTAQPESAVEVEGANNRVQLAQLERAYQARA
HHHCCCCCCCCCEEHEEHHHHHCCCCEEEEECCCCCEEEEECCCCEEEHHHHHHHHHHHH
AEKLMLEGANLRDPARIDIRGDVTVGMDVMIDINVVIEGKVTIGNNVTIGAGAILIDCEI
HHHHHHCCCCCCCCEEEEEECCEEECEEEEEEEEEEEEEEEEECCEEEEECCEEEEEEEE
SDNAVIKPYSIIESAKVGVDASAGPFARLRPGAELKQDAHIGNFVEMKKAVLGKGSKAGH
CCCCEECCHHHHHHHHCCCCCCCCCCHHCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCE
LAYIGDATIGAGVNIGAGTITCNYDGANKFQTIIEDNVFVGSDTQLVAPVTIGEGATLGA
EEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEECCCCEEEEEEEECCCCCCCC
GSTITKDVAAGELVITRVKQRHLTGWARPVKQKK
CCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA