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The map label for this gene is srlR [H]

Identifier: 167626191

GI number: 167626191

Start: 5195519

End: 5196289

Strand: Reverse

Name: srlR [H]

Synonym: Shal_4286

Alternate gene names: 167626191

Gene position: 5196289-5195519 (Counterclockwise)

Preceding gene: 167626192

Following gene: 167626190

Centisome position: 99.41

GC content: 46.69

Gene sequence:

>771_bases
ATGAACAAACGAAACACTCAACAGCGACGTCACAGCATTATTAGCCTGCTAAATCAGCAAGGCGAGGTGAGTGTTGAAGA
GCTATCTTTACGTTTCGAAACCTCTGAAGTCACTATTCGTAAAGACTTAGCCACCTTAGAGAAAACCGGCTTATTATTGC
GCCGTTATGGCGGTGCAGTCGCTGTACCCGATGAGGTGACGCAGCAGTTTTCAGCCAAGATCGCACCTAACAAATTATCG
ATTGCTAAAGCCGCAGCTCAGCTGATTAAAGATCATAACCGTATCATTATCGACAGTGGCAGTACCACATCAGGTTTGAT
CGGCGAGCTTAATAATAAGCGTGGTTTATTGGTGATGACCAATTCACTCGCACTTGCTAACTCAATTCACGAGCTTGAAA
ACGAGCCGACGTTATTGATGACGGGTGGTACATGGGATCCGCACTCAGAATCTTTTCAAGGGCAGATAGCCGAACAGGTA
TTACGTTCATACAACTTCGATCAGCTGTTTATTGGTGCCGACGGTATCGATCTTGAGCGTGGTACCACAACCTTTAATGA
GCTTACTGGCCTTAGTAAGGTGATGGCCGAGGTATCGCGAGAAGTGGTAGTGATGCTCGAGTCAGAAAAGCTGGGTCGAC
GCATTCCAAACCTTGAGCTGCCTTGGAGCAAGATCAGTGTGTTGGTAACTGACGATAAGTTACCGAGTGAAGCGCTAGAG
ACAATTTCTAATCATGGGGTGCGCGTCATTCTTGCACCTTATGCTGGGTAA

Upstream 100 bases:

>100_bases
AGAGGTTAATGGCTATCAGTATAAGTCGCATCAAAAACTGGCAATTAAGTTTCGTTTCACTATAATACTTCTTTCGAATC
GAAACTTAATGAAAGGTTTT

Downstream 100 bases:

>100_bases
CGACTACAAGCATGCAGCTTGAGTTAATTATCTACTTTCAAATTCAATTTTTAACTTTTAATTTAACTCTCCTATAGAGA
GGCTAGGTAACTAAATATGT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKTGLLLRRYGGAVAVPDEVTQQFSAKIAPNKLS
IAKAAAQLIKDHNRIIIDSGSTTSGLIGELNNKRGLLVMTNSLALANSIHELENEPTLLMTGGTWDPHSESFQGQIAEQV
LRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVLVTDDKLPSEALE
TISNHGVRVILAPYAG

Sequences:

>Translated_256_residues
MNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKTGLLLRRYGGAVAVPDEVTQQFSAKIAPNKLS
IAKAAAQLIKDHNRIIIDSGSTTSGLIGELNNKRGLLVMTNSLALANSIHELENEPTLLMTGGTWDPHSESFQGQIAEQV
LRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVLVTDDKLPSEALE
TISNHGVRVILAPYAG
>Mature_256_residues
MNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKTGLLLRRYGGAVAVPDEVTQQFSAKIAPNKLS
IAKAAAQLIKDHNRIIIDSGSTTSGLIGELNNKRGLLVMTNSLALANSIHELENEPTLLMTGGTWDPHSESFQGQIAEQV
LRSYNFDQLFIGADGIDLERGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVLVTDDKLPSEALE
TISNHGVRVILAPYAG

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=41.5322580645161, Blast_Score=194, Evalue=4e-51,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=40.9448818897638, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=30.1204819277108, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=28.2868525896414, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787540, Length=235, Percent_Identity=31.063829787234, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790635, Length=256, Percent_Identity=29.296875, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87082344, Length=244, Percent_Identity=26.6393442622951, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790753, Length=256, Percent_Identity=24.609375, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28189; Mature: 28189

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKTGLLLRRYGGAV
CCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCEEHHHHHHHHHHHHHHHHHCCCCE
AVPDEVTQQFSAKIAPNKLSIAKAAAQLIKDHNRIIIDSGSTTSGLIGELNNKRGLLVMT
ECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCEEEEE
NSLALANSIHELENEPTLLMTGGTWDPHSESFQGQIAEQVLRSYNFDQLFIGADGIDLER
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
GTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVLVTDDKLPSEALE
CCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHH
TISNHGVRVILAPYAG
HHHCCCEEEEEECCCC
>Mature Secondary Structure
MNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKTGLLLRRYGGAV
CCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCEEHHHHHHHHHHHHHHHHHCCCCE
AVPDEVTQQFSAKIAPNKLSIAKAAAQLIKDHNRIIIDSGSTTSGLIGELNNKRGLLVMT
ECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHCCCCCCCEEEEE
NSLALANSIHELENEPTLLMTGGTWDPHSESFQGQIAEQVLRSYNFDQLFIGADGIDLER
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
GTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVLVTDDKLPSEALE
CCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHH
TISNHGVRVILAPYAG
HHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]