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The map label for this gene is pdxH

Identifier: 167623736

GI number: 167623736

Start: 2159583

End: 2160221

Strand: Direct

Name: pdxH

Synonym: Shal_1806

Alternate gene names: 167623736

Gene position: 2159583-2160221 (Clockwise)

Preceding gene: 167623735

Following gene: 167623737

Centisome position: 41.32

GC content: 44.76

Gene sequence:

>639_bases
ATGTCAGAACTTAGCGATATCAGACGTGAATACACGTTAGGCGAATTACATAGCGAAGATGTGCCCAATGACCCTATGGA
CCTGTTTAACGCCTGGCTTGAAGTCGTTCGAGACTCACAGATTCAAGATCCCACCGCGATGTCTGTTGCGACTGTGGACG
AGAATGGTCAGCCTTTTCAAAGAATAGTGTTACTAAAGCGATTTGGTGATGATGGTTTTGTATTTTTTACCAATCTCGAA
AGCCGTAAAGCGCAGCACATTGCCAATAATGCTCAGGTCAGTATTTTATTTCCGTGGCACAGTATAGATAAACAGGTAGC
CGTTACAGGTATCGCCGAGCCTTTATCTAAAACTGAGGTGCTTAAATATTTTATGAGCCGACCTAAAGAGAGTCAGATAG
CCGCCTGGGTCTCAAAGCAATCTAGCCCAATTAGTGCCAGAAAGGCGCTAGAAACTAAATTTGCGGAGATGAAGGCTAAG
TTCTCTAAGGGAGATGTGCCTTTACCTAAATTTTGGGGAGGCTACCTAGTTCGGCCTAAAAGTATTGAGTTCTGGCAGGG
CGGAGAGCACCGTTTGCATGATAGGTTTATTTATACCAAAGTCGGTGATGACTGGGTGCGTAGTCGTTTAGCGCCATAA

Upstream 100 bases:

>100_bases
GCCTATCAAAAGGCTCCCGTCCAATGCTTAAGATTGTTATCATTAAAGAAGCGCTAAATTAAGCGCTTCTTTTTTTTTGG
TTCGATGAAAGGATTGATAA

Downstream 100 bases:

>100_bases
TTATACCAATCACACATTTAGTACGATTGGTATTAAATACACAAAAGCCGCATACCATGCGGCTTTTGTATATTTTGCGA
TCCGTCCTAATATTAAGAGT

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSELSDIRREYTLGELHSEDVPNDPMDLFNAWLEVVRDSQIQDPTAMSVATVDENGQPFQRIVLLKRFGDDGFVFFTNLE
SRKAQHIANNAQVSILFPWHSIDKQVAVTGIAEPLSKTEVLKYFMSRPKESQIAAWVSKQSSPISARKALETKFAEMKAK
FSKGDVPLPKFWGGYLVRPKSIEFWQGGEHRLHDRFIYTKVGDDWVRSRLAP

Sequences:

>Translated_212_residues
MSELSDIRREYTLGELHSEDVPNDPMDLFNAWLEVVRDSQIQDPTAMSVATVDENGQPFQRIVLLKRFGDDGFVFFTNLE
SRKAQHIANNAQVSILFPWHSIDKQVAVTGIAEPLSKTEVLKYFMSRPKESQIAAWVSKQSSPISARKALETKFAEMKAK
FSKGDVPLPKFWGGYLVRPKSIEFWQGGEHRLHDRFIYTKVGDDWVRSRLAP
>Mature_211_residues
SELSDIRREYTLGELHSEDVPNDPMDLFNAWLEVVRDSQIQDPTAMSVATVDENGQPFQRIVLLKRFGDDGFVFFTNLES
RKAQHIANNAQVSILFPWHSIDKQVAVTGIAEPLSKTEVLKYFMSRPKESQIAAWVSKQSSPISARKALETKFAEMKAKF
SKGDVPLPKFWGGYLVRPKSIEFWQGGEHRLHDRFIYTKVGDDWVRSRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=205, Percent_Identity=42.9268292682927, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1787926, Length=212, Percent_Identity=59.9056603773585, Blast_Score=274, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17553712, Length=220, Percent_Identity=33.1818181818182, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=36.8421052631579, Blast_Score=138, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24644901, Length=206, Percent_Identity=42.7184466019417, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI45551845, Length=206, Percent_Identity=42.7184466019417, Blast_Score=153, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24644903, Length=176, Percent_Identity=28.4090909090909, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_SHEHH (B0TQX6)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674030.1
- ProteinModelPortal:   B0TQX6
- SMR:   B0TQX6
- GeneID:   5902627
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1806
- HOGENOM:   HBG327559
- OMA:   FTFFTNY
- ProtClustDB:   CLSK982155
- BioCyc:   SHAL458817:SHAL_1806-MONOMER
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190
- TIGRFAMs:   TIGR00558

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 24258; Mature: 24127

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 61-61 BINDING 64-64 BINDING 66-66 BINDING 83-83 BINDING 123-123 BINDING 127-127 BINDING 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSDIRREYTLGELHSEDVPNDPMDLFNAWLEVVRDSQIQDPTAMSVATVDENGQPFQ
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHH
RIVLLKRFGDDGFVFFTNLESRKAQHIANNAQVSILFPWHSIDKQVAVTGIAEPLSKTEV
HHHHHHHCCCCCEEEEECCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LKYFMSRPKESQIAAWVSKQSSPISARKALETKFAEMKAKFSKGDVPLPKFWGGYLVRPK
HHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEECCC
SIEFWQGGEHRLHDRFIYTKVGDDWVRSRLAP
CCCCCCCCCCCHHCEEEEEECCHHHHHHCCCC
>Mature Secondary Structure 
SELSDIRREYTLGELHSEDVPNDPMDLFNAWLEVVRDSQIQDPTAMSVATVDENGQPFQ
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHH
RIVLLKRFGDDGFVFFTNLESRKAQHIANNAQVSILFPWHSIDKQVAVTGIAEPLSKTEV
HHHHHHHCCCCCEEEEECCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LKYFMSRPKESQIAAWVSKQSSPISARKALETKFAEMKAKFSKGDVPLPKFWGGYLVRPK
HHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEECCC
SIEFWQGGEHRLHDRFIYTKVGDDWVRSRLAP
CCCCCCCCCCCHHCEEEEEECCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA