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The map label for this gene is lolE [H]

Identifier: 167623548

GI number: 167623548

Start: 1942938

End: 1944191

Strand: Direct

Name: lolE [H]

Synonym: Shal_1617

Alternate gene names: 167623548

Gene position: 1942938-1944191 (Clockwise)

Preceding gene: 167623547

Following gene: 167623550

Centisome position: 37.17

GC content: 45.61

Gene sequence:

>1254_bases
ATGAGAAGTTTGTTAGCGATGTGGGTTGGCTGGCGCTTCTATTTAGCGCGTCAGTCCAATCGATTTATTAACTTTATCTC
GTTTGCGTCAACCGCGGGGATCGCGCTCGGTGTGACCGTGCTTATCGTCGTGTTATCGGCGATGAATGGTTTTGAAAAAG
AGTTAGAGCATCGCTTGTTAGGCGTAGTGTCACATGGTGAGTTAATTGGTGTTAATGAGCCGATTCATCAATGGCAATCC
ATCGTCAGTGATGCCAATAAAGTGCCGGGGATCACCGCCGCTGCGCCGTTTGTGCGTATGCAGGGTTTAGTACAAAAAGT
CGGTGGCTTTCAAGCTTTGACTGTACTGGGGATCGACATCAACACCGAATCCAAAGTCTCGAACATTCAGCAGTTTATGT
CTGCCAAGAGCTGGCAGAGCCTAGGCGAGCAAAACACTAATAATATCGTTCTTGGTAAGGGATTAGCTAAGAGTTTAGAT
TTAAAGGTTGGTCAGTCGTTAAGCTTGTATATGCCCAATATCAATGGCCAGTCACAAAGTAAAATTGGCGCGGCTAAAAG
TCATCGTTTCGTGGTTTCGGGCATTTTTGAGCTTGGCGGTGAGCTGGATATGACCACAGCTTATATTCCGATGCAATATG
CCGCAAAGACCTTGAACTTAGGTGACAACGTTTCGGGTGTGCGCATTAAAGTTGACGACGTATTTGCTGCACCAAGACTG
ATAAGAGACTTAGGTTATAGCCAGCAGCAATATGTGTATATTTCTGATTGGACTCGCACTCAAGGTCACCTATATCAAGA
TATTCAACTGGTGCGTATGGTGATGTATCTGGTGCTTGCGTTAGTGATCGCCGTGGCTTGCTTTAATATTGTGTCGACCT
TAGTGATGGCGGTGCGAGATAAACAGTCCGAAATTGCTATCTTACTCACCATGGGCATGAGAAAAGCATCAATCATGCTG
ATCTTTATCGTCCAAGGTGCCTTTAATGGCATTTTGGGCTGCGCCATTGGCGGCGTATTAGGGGTGATGATTTCGCTTAA
TTTAAGTGCCATAGCACGCACGATAGAGTCAGTATTAGGCGTTCAGCTGTTATCGGCAGATGTATACTTTATTGATTTTT
TACCTTCGCAGCTAAAAAGTGGTGATGTGATAACCGTTGTCTGTTTAGCCTTTGTGATGAGTGTTATCGCGACTTTATAT
CCTGCGTGGAAAGCGAGCCAAACTCCGCCTGCGAGAGCATTGGCCGGAAGATAA

Upstream 100 bases:

>100_bases
CATTTGTTGTAGTGACTCACGATCAAAGCTTAGCGGCAAGAATGGATAGGCAGCTGCATATGAAAGATGGCCGCTTGGTG
CAAGCCGAGGAACTTAACGC

Downstream 100 bases:

>100_bases
TTCCGCTAGGTATAAGCTCTGCAAGTTTAAAAATAACGCCAGCATCTGCTGGCGTTGGTCTTTTTGGCTTACCTATTGCC
GTAGAGGAAGCAATAAAGAA

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MRSLLAMWVGWRFYLARQSNRFINFISFASTAGIALGVTVLIVVLSAMNGFEKELEHRLLGVVSHGELIGVNEPIHQWQS
IVSDANKVPGITAAAPFVRMQGLVQKVGGFQALTVLGIDINTESKVSNIQQFMSAKSWQSLGEQNTNNIVLGKGLAKSLD
LKVGQSLSLYMPNINGQSQSKIGAAKSHRFVVSGIFELGGELDMTTAYIPMQYAAKTLNLGDNVSGVRIKVDDVFAAPRL
IRDLGYSQQQYVYISDWTRTQGHLYQDIQLVRMVMYLVLALVIAVACFNIVSTLVMAVRDKQSEIAILLTMGMRKASIML
IFIVQGAFNGILGCAIGGVLGVMISLNLSAIARTIESVLGVQLLSADVYFIDFLPSQLKSGDVITVVCLAFVMSVIATLY
PAWKASQTPPARALAGR

Sequences:

>Translated_417_residues
MRSLLAMWVGWRFYLARQSNRFINFISFASTAGIALGVTVLIVVLSAMNGFEKELEHRLLGVVSHGELIGVNEPIHQWQS
IVSDANKVPGITAAAPFVRMQGLVQKVGGFQALTVLGIDINTESKVSNIQQFMSAKSWQSLGEQNTNNIVLGKGLAKSLD
LKVGQSLSLYMPNINGQSQSKIGAAKSHRFVVSGIFELGGELDMTTAYIPMQYAAKTLNLGDNVSGVRIKVDDVFAAPRL
IRDLGYSQQQYVYISDWTRTQGHLYQDIQLVRMVMYLVLALVIAVACFNIVSTLVMAVRDKQSEIAILLTMGMRKASIML
IFIVQGAFNGILGCAIGGVLGVMISLNLSAIARTIESVLGVQLLSADVYFIDFLPSQLKSGDVITVVCLAFVMSVIATLY
PAWKASQTPPARALAGR
>Mature_417_residues
MRSLLAMWVGWRFYLARQSNRFINFISFASTAGIALGVTVLIVVLSAMNGFEKELEHRLLGVVSHGELIGVNEPIHQWQS
IVSDANKVPGITAAAPFVRMQGLVQKVGGFQALTVLGIDINTESKVSNIQQFMSAKSWQSLGEQNTNNIVLGKGLAKSLD
LKVGQSLSLYMPNINGQSQSKIGAAKSHRFVVSGIFELGGELDMTTAYIPMQYAAKTLNLGDNVSGVRIKVDDVFAAPRL
IRDLGYSQQQYVYISDWTRTQGHLYQDIQLVRMVMYLVLALVIAVACFNIVSTLVMAVRDKQSEIAILLTMGMRKASIML
IFIVQGAFNGILGCAIGGVLGVMISLNLSAIARTIESVLGVQLLSADVYFIDFLPSQLKSGDVITVVCLAFVMSVIATLY
PAWKASQTPPARALAGR

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=415, Percent_Identity=44.8192771084337, Blast_Score=341, Evalue=4e-95,
Organism=Escherichia coli, GI1787360, Length=419, Percent_Identity=31.0262529832936, Blast_Score=164, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45298; Mature: 45298

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLLAMWVGWRFYLARQSNRFINFISFASTAGIALGVTVLIVVLSAMNGFEKELEHRLL
CHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GVVSHGELIGVNEPIHQWQSIVSDANKVPGITAAAPFVRMQGLVQKVGGFQALTVLGIDI
HHCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEC
NTESKVSNIQQFMSAKSWQSLGEQNTNNIVLGKGLAKSLDLKVGQSLSLYMPNINGQSQS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCCEEEEECCCCCCCCH
KIGAAKSHRFVVSGIFELGGELDMTTAYIPMQYAAKTLNLGDNVSGVRIKVDDVFAAPRL
HCCCHHCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHH
IRDLGYSQQQYVYISDWTRTQGHLYQDIQLVRMVMYLVLALVIAVACFNIVSTLVMAVRD
HHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KQSEIAILLTMGMRKASIMLIFIVQGAFNGILGCAIGGVLGVMISLNLSAIARTIESVLG
CCCCEEEEEEECCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLLSADVYFIDFLPSQLKSGDVITVVCLAFVMSVIATLYPAWKASQTPPARALAGR
HHHHHCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MRSLLAMWVGWRFYLARQSNRFINFISFASTAGIALGVTVLIVVLSAMNGFEKELEHRLL
CHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
GVVSHGELIGVNEPIHQWQSIVSDANKVPGITAAAPFVRMQGLVQKVGGFQALTVLGIDI
HHCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEC
NTESKVSNIQQFMSAKSWQSLGEQNTNNIVLGKGLAKSLDLKVGQSLSLYMPNINGQSQS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCCEEEEECCCCCCCCH
KIGAAKSHRFVVSGIFELGGELDMTTAYIPMQYAAKTLNLGDNVSGVRIKVDDVFAAPRL
HCCCHHCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHH
IRDLGYSQQQYVYISDWTRTQGHLYQDIQLVRMVMYLVLALVIAVACFNIVSTLVMAVRD
HHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KQSEIAILLTMGMRKASIMLIFIVQGAFNGILGCAIGGVLGVMISLNLSAIARTIESVLG
CCCCEEEEEEECCCHHHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQLLSADVYFIDFLPSQLKSGDVITVVCLAFVMSVIATLYPAWKASQTPPARALAGR
HHHHHCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10783239 [H]