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The map label for this gene is wecA [H]

Identifier: 167623430

GI number: 167623430

Start: 1802396

End: 1803442

Strand: Direct

Name: wecA [H]

Synonym: Shal_1499

Alternate gene names: 167623430

Gene position: 1802396-1803442 (Clockwise)

Preceding gene: 167623429

Following gene: 167623432

Centisome position: 34.48

GC content: 39.73

Gene sequence:

>1047_bases
ATGAGTTTAATCGAGCCATTCTCCTTGGCATTTTTATTGAGTTTTGTTGTAATTAAATTTTCAGCTCCCTATGCCTCGAA
GGTAGGGTTGGTTGACCTACCCAATGCTCGTAAAGTTCATGATGGCGCTGTACCTCTAATCGGTGGTATTGGTATTTTCT
TTAGTGTATTGCTCGCTTCGTCAGTTTTCATTGAGTACAGCAGAGTCTTAAATCTTTACCTTATCTCAGCCGCGTTGATT
TTGTTTATCGGGGTACTCGATGACCGCTACGACCTTTCGGTTCGCTTACGAATGATAGCTCAAGTGATAACTGCATCAAT
CTTGATCTTTGGTGCAGAATCTTATTTAACCTCACTAGGGAGTATCTTTTATTTCTTCGAGTTTAAACTAGGCTACTTAG
GAATATTGGTCACGGTAATCGCTGTCATTGGTTCTATCAATGCGTTTAACATGGTTGATGGTATCGATGGATTAGCTGGT
ATGTTGAGTATCGTAACATTTGCAGCACTAGCATTTCTGTTCTATCAAGTTGGTAATCCTTGGTTCGTATTACCAATATT
GTTTATCGCAGCAATTACAGCTTACCTTTGTTTCAATTTACGCTGGCCATTTTCTTCAATTCAAAAAGTGTTTATGGGCG
ATGCAGGTAGTATGTTGATCGGCCTAACTGTGGTTTGGTTACTCGTGACAGGTACGGAGTCGGTTAATCAAGCATTTTCA
CCTGTTATCGCTCTTTACCTGATTGCTATCCCATTGATGGATATGGCTGCAATTATGTATCGAAGAGTAAAGAAGGGGCA
TTCTCCGTTCAAACCAGATAGAGACCATCTTCACCATATATTTGAACGTGCAGGTTATAGCCGTAAACAGACTTTAGCTC
GAATTACATTGTTGTCAGCAATACTTGCAACGATAGGTGTTTTAGGTGAATTACTTGCCGTTCCTGAAGTCATGATGTTT
ATTGGGTTTTTAGTTATTTTTGTTGCATATAATTGGGCGTTAGCGCATGTATGGCAGATTTTAACTTGGATTAGACGTAA
CGGCTAA

Upstream 100 bases:

>100_bases
TTTGGATATTTTAGATAGCTTTTATAATTGACGGATTAGTTGTAAACTTGCCTATCAAAATGGGTGATTACCGCTTTTAC
TTGTACTTAAGGATAAGAAA

Downstream 100 bases:

>100_bases
AGCTGACCTTATATTTATTTAGAAAATCTCCTAATTGGGGATTTTCTTGTTTGTAGGCTTTAAAAAGGCAAGAAAGTTCT
AGATTTTGGAATAGCAGGTT

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSLIEPFSLAFLLSFVVIKFSAPYASKVGLVDLPNARKVHDGAVPLIGGIGIFFSVLLASSVFIEYSRVLNLYLISAALI
LFIGVLDDRYDLSVRLRMIAQVITASILIFGAESYLTSLGSIFYFFEFKLGYLGILVTVIAVIGSINAFNMVDGIDGLAG
MLSIVTFAALAFLFYQVGNPWFVLPILFIAAITAYLCFNLRWPFSSIQKVFMGDAGSMLIGLTVVWLLVTGTESVNQAFS
PVIALYLIAIPLMDMAAIMYRRVKKGHSPFKPDRDHLHHIFERAGYSRKQTLARITLLSAILATIGVLGELLAVPEVMMF
IGFLVIFVAYNWALAHVWQILTWIRRNG

Sequences:

>Translated_348_residues
MSLIEPFSLAFLLSFVVIKFSAPYASKVGLVDLPNARKVHDGAVPLIGGIGIFFSVLLASSVFIEYSRVLNLYLISAALI
LFIGVLDDRYDLSVRLRMIAQVITASILIFGAESYLTSLGSIFYFFEFKLGYLGILVTVIAVIGSINAFNMVDGIDGLAG
MLSIVTFAALAFLFYQVGNPWFVLPILFIAAITAYLCFNLRWPFSSIQKVFMGDAGSMLIGLTVVWLLVTGTESVNQAFS
PVIALYLIAIPLMDMAAIMYRRVKKGHSPFKPDRDHLHHIFERAGYSRKQTLARITLLSAILATIGVLGELLAVPEVMMF
IGFLVIFVAYNWALAHVWQILTWIRRNG
>Mature_347_residues
SLIEPFSLAFLLSFVVIKFSAPYASKVGLVDLPNARKVHDGAVPLIGGIGIFFSVLLASSVFIEYSRVLNLYLISAALIL
FIGVLDDRYDLSVRLRMIAQVITASILIFGAESYLTSLGSIFYFFEFKLGYLGILVTVIAVIGSINAFNMVDGIDGLAGM
LSIVTFAALAFLFYQVGNPWFVLPILFIAAITAYLCFNLRWPFSSIQKVFMGDAGSMLIGLTVVWLLVTGTESVNQAFSP
VIALYLIAIPLMDMAAIMYRRVKKGHSPFKPDRDHLHHIFERAGYSRKQTLARITLLSAILATIGVLGELLAVPEVMMFI
GFLVIFVAYNWALAHVWQILTWIRRNG

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=323, Percent_Identity=46.1300309597523, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012750
- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 38485; Mature: 38353

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIEPFSLAFLLSFVVIKFSAPYASKVGLVDLPNARKVHDGAVPLIGGIGIFFSVLLAS
CCCCCHHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
SVFIEYSRVLNLYLISAALILFIGVLDDRYDLSVRLRMIAQVITASILIFGAESYLTSLG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIFYFFEFKLGYLGILVTVIAVIGSINAFNMVDGIDGLAGMLSIVTFAALAFLFYQVGNP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WFVLPILFIAAITAYLCFNLRWPFSSIQKVFMGDAGSMLIGLTVVWLLVTGTESVNQAFS
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHH
PVIALYLIAIPLMDMAAIMYRRVKKGHSPFKPDRDHLHHIFERAGYSRKQTLARITLLSA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
ILATIGVLGELLAVPEVMMFIGFLVIFVAYNWALAHVWQILTWIRRNG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLIEPFSLAFLLSFVVIKFSAPYASKVGLVDLPNARKVHDGAVPLIGGIGIFFSVLLAS
CCCCHHHHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]