Click here to switch to the map view.

The map label for this gene is wecA [H]

Identifier: 167623429

GI number: 167623429

Start: 1801152

End: 1802228

Strand: Direct

Name: wecA [H]

Synonym: Shal_1498

Alternate gene names: 167623429

Gene position: 1801152-1802228 (Clockwise)

Preceding gene: 167623428

Following gene: 167623430

Centisome position: 34.46

GC content: 37.51

Gene sequence:

>1077_bases
ATGAGTTACAGTTTAATTTTTGCCTTTTTTATCTCTTTCCTCTGTCTTTTTCTATTCAGAAAAATAGCAAAACGTATTGG
GTTAGTCGATAAGCCTAATCAGCGAAAACACCATGAAGGTCAGATCCCGCTTGTTGGCGGGATCTCCATATTTCTTAGTC
TTATGTTTACGCTATTGGTTTTTATACCACTTGATAAAAATATCGTGTTGTATATTTGTTGCTCTACTATTTTGATTGTT
TTGGGGGCAATTGATGACAGATTTGATATCAGCTTTAAAGTTCGGTTAGTCATTCAAGCTGTTATATCACTAGCGATGAT
TCTTGTTGGTGAAAAAAGCTTACATAATCTTGGCTACTTAATGGGGAGTGAAGTTATTCAGCTTCCTCTGGTTGTTAGTT
ACTTAGTAACCATATTCGGGGTGATTGGCGCAATTAATGCCTTCAATATGGTTGATGGTATCGACGGTTTGTTAGGCGGC
TTAGCTTCAGTTACCTTTGGTGCGTTAGGTGTTCTTTTTTATCATAGTGGTAACTATGAGTTAGCCAAATACTGTTTGTT
GATCGTCGCTGCTATTTTACCTTATATAATGCTCAATTTAGGGATACCTCTAGGGCAACGTTTCAAGGTATTTATGGGCG
ACGCTGGTAGCATTTTTATTGGTTTTACTGTTATTTGGTTATTGATAGAAGCCAGTCAGGGAGAAAGTCATAATGCTATT
CGGCCAGTTACCGCACTTTGGCTAATTGCTTTACCTCTAATGGATATGGTTTGCATTATGGTAAGGCGGATCAGGAAAGG
GCAATCGCCTTTTAAACCAGATAGAGAGCATCTGCATCATATTTGCCAGCGTATTGGTTTTACGTCTCGAGGTTCGTTAT
TGGTTATTTGCTTTTTAGCGAGCATCATGGCGGGTGTAGGAATTTGGTCCGAGCTAAATGGTATTAACGAAACCGTTATG
TTTATTACCTTTTTAATTGTGTTTGCAGTCTATTTTTACGTTATAGCCCACATTTGGAAAATTACAGCTTTCATTAAGAA
AAAAATGAAGGTTCCAGTTACTTCTCTAAAATCATAG

Upstream 100 bases:

>100_bases
AGAGAAGCGATATACATGGGAAATCATTACTAAGATGTATGAAGATACTTATACCTAGTTTTTAATCTTTTTAATTAGTA
CGTAATAAGTAGTAGGTAGT

Downstream 100 bases:

>100_bases
CCTGCTAACCAAATTGGGCTTAAGCATTAATCACAAGTACTATTTGTAGCCTGTAGATATAAGCTCATTTGGATATTTTA
GATAGCTTTTATAATTGACG

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSYSLIFAFFISFLCLFLFRKIAKRIGLVDKPNQRKHHEGQIPLVGGISIFLSLMFTLLVFIPLDKNIVLYICCSTILIV
LGAIDDRFDISFKVRLVIQAVISLAMILVGEKSLHNLGYLMGSEVIQLPLVVSYLVTIFGVIGAINAFNMVDGIDGLLGG
LASVTFGALGVLFYHSGNYELAKYCLLIVAAILPYIMLNLGIPLGQRFKVFMGDAGSIFIGFTVIWLLIEASQGESHNAI
RPVTALWLIALPLMDMVCIMVRRIRKGQSPFKPDREHLHHICQRIGFTSRGSLLVICFLASIMAGVGIWSELNGINETVM
FITFLIVFAVYFYVIAHIWKITAFIKKKMKVPVTSLKS

Sequences:

>Translated_358_residues
MSYSLIFAFFISFLCLFLFRKIAKRIGLVDKPNQRKHHEGQIPLVGGISIFLSLMFTLLVFIPLDKNIVLYICCSTILIV
LGAIDDRFDISFKVRLVIQAVISLAMILVGEKSLHNLGYLMGSEVIQLPLVVSYLVTIFGVIGAINAFNMVDGIDGLLGG
LASVTFGALGVLFYHSGNYELAKYCLLIVAAILPYIMLNLGIPLGQRFKVFMGDAGSIFIGFTVIWLLIEASQGESHNAI
RPVTALWLIALPLMDMVCIMVRRIRKGQSPFKPDREHLHHICQRIGFTSRGSLLVICFLASIMAGVGIWSELNGINETVM
FITFLIVFAVYFYVIAHIWKITAFIKKKMKVPVTSLKS
>Mature_357_residues
SYSLIFAFFISFLCLFLFRKIAKRIGLVDKPNQRKHHEGQIPLVGGISIFLSLMFTLLVFIPLDKNIVLYICCSTILIVL
GAIDDRFDISFKVRLVIQAVISLAMILVGEKSLHNLGYLMGSEVIQLPLVVSYLVTIFGVIGAINAFNMVDGIDGLLGGL
ASVTFGALGVLFYHSGNYELAKYCLLIVAAILPYIMLNLGIPLGQRFKVFMGDAGSIFIGFTVIWLLIEASQGESHNAIR
PVTALWLIALPLMDMVCIMVRRIRKGQSPFKPDREHLHHICQRIGFTSRGSLLVICFLASIMAGVGIWSELNGINETVMF
ITFLIVFAVYFYVIAHIWKITAFIKKKMKVPVTSLKS

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55). It is the first lipid-linked intermediate involved in enterobacter

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=329, Percent_Identity=53.4954407294833, Blast_Score=338, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012750
- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39831; Mature: 39700

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSLIFAFFISFLCLFLFRKIAKRIGLVDKPNQRKHHEGQIPLVGGISIFLSLMFTLLV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
FIPLDKNIVLYICCSTILIVLGAIDDRFDISFKVRLVIQAVISLAMILVGEKSLHNLGYL
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MGSEVIQLPLVVSYLVTIFGVIGAINAFNMVDGIDGLLGGLASVTFGALGVLFYHSGNYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAKYCLLIVAAILPYIMLNLGIPLGQRFKVFMGDAGSIFIGFTVIWLLIEASQGESHNAI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCH
RPVTALWLIALPLMDMVCIMVRRIRKGQSPFKPDREHLHHICQRIGFTSRGSLLVICFLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
SIMAGVGIWSELNGINETVMFITFLIVFAVYFYVIAHIWKITAFIKKKMKVPVTSLKS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
SYSLIFAFFISFLCLFLFRKIAKRIGLVDKPNQRKHHEGQIPLVGGISIFLSLMFTLLV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
FIPLDKNIVLYICCSTILIVLGAIDDRFDISFKVRLVIQAVISLAMILVGEKSLHNLGYL
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MGSEVIQLPLVVSYLVTIFGVIGAINAFNMVDGIDGLLGGLASVTFGALGVLFYHSGNYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAKYCLLIVAAILPYIMLNLGIPLGQRFKVFMGDAGSIFIGFTVIWLLIEASQGESHNAI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCH
RPVTALWLIALPLMDMVCIMVRRIRKGQSPFKPDREHLHHICQRIGFTSRGSLLVICFLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
SIMAGVGIWSELNGINETVMFITFLIVFAVYFYVIAHIWKITAFIKKKMKVPVTSLKS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]