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The map label for this gene is argA [H]

Identifier: 167622372

GI number: 167622372

Start: 506236

End: 507558

Strand: Direct

Name: argA [H]

Synonym: Shal_0432

Alternate gene names: 167622372

Gene position: 506236-507558 (Clockwise)

Preceding gene: 167622371

Following gene: 167622373

Centisome position: 9.69

GC content: 49.74

Gene sequence:

>1323_bases
GTGCGTACCACAGAACTTGTTGATGGATTTCGTCATTCCGCTTCCTATGTGAATGCCCATAGGGGCAAAACCTTCGTCGT
TATGTTGGGTGGCGAGGCTATCGCACAGCAACAGTTTCGCGCCATCATCAATGATATTGCGCTACTGCACAGCCTTGGGA
TTAAGATAGTCCTTGTTCATGGCGCTAGGCCGCAGATAGATGAAGCGTTGGCCGAGCGCAGTTTGGCTGCCGAATATTAC
AATGGTGTGAGAGTCACGGAAGAAGACGCGCTTAAGGTCATTAAACAAGTGGTAGGTGCTTTGCACCTCGATATCACCGC
GCGCCTATCGATGAGTCTAAGTAACACGCCAATGCAGGGCGCACAGATCAACGTGGTCAGCGGTAACTTTGTCATTGCTC
AGCCATTAGGGGTCGAGGATGGTGTCGATTATTGTCTCAGCGGTAAGGTGCGTCGTATTGACAGCCTGGGGCTGAAGCGT
CAGCTCGACAGTGGTGGTATCGTATTACTTGGCCCTGTAGCAGCCTCTGTGACGGGGGAGAGCTTTAATCTAACTGCAGA
AGAGGTTGCCACCCAGATTGCAATAAAACTCAAAGCAGACAAGATGATAGGCTTTAGCGCCGAGAAAGGTATTTTAGATA
ACTATGGTCAGGTTGTCGCTGAGTTGATGCCCACCGAAGCGCAAAAGATCTTAAATGAGTTTCCCGAGGTCTCTCCATTG
TGTGTTGGCACCAAGGCTTTCTTGGAGGCCAGCATCGATGCTTGTCGCAATGGGGTCAGTCGCTGTCACTTTGTGAGTTA
TCTCGATGATGGTGCACTGTTGCAAGAGCTCTTCTCCCGCGATGGTATCGGCACGCAGATTGTAACCGAAAGCGCCGAGC
GTCTACGTAGAGCAACGATCAGTGATATCGGCGGCATATTAGATCTTATCCGCCCACTGGAGCAGAAAGGGATCTTAGTG
CGGCGCTCACGTGAGCAGCTAGAGGTGGAGATAGAGCAGTTTATGTTAATTGAGCGCGACAGCCTAGTGATCGGCTGCGC
GGCGTTTTATCCATTTGAGGAGGATAATGCGGGTGAGTTTGCCTGTTTAGTGGTGCATCCCGACTACCGCGATGCCGATA
GAGGCAGCTTGCTACTACAAAATATTATTGGTCAGGCAAGAGTGAGAGGCTATTCGCGTTTGTTTGCCTTAACGACCCGC
AGTATCCATTGGTTCTTAGAGCATGGGTTTAATATGGTTGAAGTTGAAGCGTTGCCAGAGAAGAAAAAGCAGCTGTATAA
CTATCAACGCAAATCGAAGATTTTAGCGCTAGACTTATACTGA

Upstream 100 bases:

>100_bases
AATGAATTTAAATGCACTATTATCTTTGGGTATAACTGAGCTAATTATCAAATATGAAGCTTCGGATATCTTTCCTATCT
ATTTTAAAGGTGATGTTAAC

Downstream 100 bases:

>100_bases
TTGGTATTTGAGTCATATGGAAGAAAGGCTTAAAGGATGACAAAAGTTATTGTCATCTAAAAATCTGAACACCATAGCTA
ATTAGGAGCGCCCATGCCTC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEAIAQQQFRAIINDIALLHSLGIKIVLVHGARPQIDEALAERSLAAEYY
NGVRVTEEDALKVIKQVVGALHLDITARLSMSLSNTPMQGAQINVVSGNFVIAQPLGVEDGVDYCLSGKVRRIDSLGLKR
QLDSGGIVLLGPVAASVTGESFNLTAEEVATQIAIKLKADKMIGFSAEKGILDNYGQVVAELMPTEAQKILNEFPEVSPL
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRATISDIGGILDLIRPLEQKGILV
RRSREQLEVEIEQFMLIERDSLVIGCAAFYPFEEDNAGEFACLVVHPDYRDADRGSLLLQNIIGQARVRGYSRLFALTTR
SIHWFLEHGFNMVEVEALPEKKKQLYNYQRKSKILALDLY

Sequences:

>Translated_440_residues
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEAIAQQQFRAIINDIALLHSLGIKIVLVHGARPQIDEALAERSLAAEYY
NGVRVTEEDALKVIKQVVGALHLDITARLSMSLSNTPMQGAQINVVSGNFVIAQPLGVEDGVDYCLSGKVRRIDSLGLKR
QLDSGGIVLLGPVAASVTGESFNLTAEEVATQIAIKLKADKMIGFSAEKGILDNYGQVVAELMPTEAQKILNEFPEVSPL
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRATISDIGGILDLIRPLEQKGILV
RRSREQLEVEIEQFMLIERDSLVIGCAAFYPFEEDNAGEFACLVVHPDYRDADRGSLLLQNIIGQARVRGYSRLFALTTR
SIHWFLEHGFNMVEVEALPEKKKQLYNYQRKSKILALDLY
>Mature_440_residues
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEAIAQQQFRAIINDIALLHSLGIKIVLVHGARPQIDEALAERSLAAEYY
NGVRVTEEDALKVIKQVVGALHLDITARLSMSLSNTPMQGAQINVVSGNFVIAQPLGVEDGVDYCLSGKVRRIDSLGLKR
QLDSGGIVLLGPVAASVTGESFNLTAEEVATQIAIKLKADKMIGFSAEKGILDNYGQVVAELMPTEAQKILNEFPEVSPL
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRATISDIGGILDLIRPLEQKGILV
RRSREQLEVEIEQFMLIERDSLVIGCAAFYPFEEDNAGEFACLVVHPDYRDADRGSLLLQNIIGQARVRGYSRLFALTTR
SIHWFLEHGFNMVEVEALPEKKKQLYNYQRKSKILALDLY

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=438, Percent_Identity=64.8401826484018, Blast_Score=603, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6320913, Length=303, Percent_Identity=20.7920792079208, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 48552; Mature: 48552

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEAIAQQQFRAIINDIALLHSLGIKIVLVH
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GARPQIDEALAERSLAAEYYNGVRVTEEDALKVIKQVVGALHLDITARLSMSLSNTPMQG
CCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCC
AQINVVSGNFVIAQPLGVEDGVDYCLSGKVRRIDSLGLKRQLDSGGIVLLGPVAASVTGE
CEEEEEECCEEEEECCCCCCCCHHHHCCCHHHHHHHCHHHCCCCCCEEEEECCEEEECCC
SFNLTAEEVATQIAIKLKADKMIGFSAEKGILDNYGQVVAELMPTEAQKILNEFPEVSPL
CCCCCHHHHHHHHHEEEEECCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCE
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRATI
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDIGGILDLIRPLEQKGILVRRSREQLEVEIEQFMLIERDSLVIGCAAFYPFEEDNAGEF
HHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHEEECCCEEEEEEEECCCCCCCCCCE
ACLVVHPDYRDADRGSLLLQNIIGQARVRGYSRLFALTTRSIHWFLEHGFNMVEVEALPE
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCH
KKKQLYNYQRKSKILALDLY
HHHHHHHHHHHCEEEEEECC
>Mature Secondary Structure
MRTTELVDGFRHSASYVNAHRGKTFVVMLGGEAIAQQQFRAIINDIALLHSLGIKIVLVH
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
GARPQIDEALAERSLAAEYYNGVRVTEEDALKVIKQVVGALHLDITARLSMSLSNTPMQG
CCCCCHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCC
AQINVVSGNFVIAQPLGVEDGVDYCLSGKVRRIDSLGLKRQLDSGGIVLLGPVAASVTGE
CEEEEEECCEEEEECCCCCCCCHHHHCCCHHHHHHHCHHHCCCCCCEEEEECCEEEECCC
SFNLTAEEVATQIAIKLKADKMIGFSAEKGILDNYGQVVAELMPTEAQKILNEFPEVSPL
CCCCCHHHHHHHHHEEEEECCEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCE
CVGTKAFLEASIDACRNGVSRCHFVSYLDDGALLQELFSRDGIGTQIVTESAERLRRATI
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDIGGILDLIRPLEQKGILVRRSREQLEVEIEQFMLIERDSLVIGCAAFYPFEEDNAGEF
HHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHEEECCCEEEEEEEECCCCCCCCCCE
ACLVVHPDYRDADRGSLLLQNIIGQARVRGYSRLFALTTRSIHWFLEHGFNMVEVEALPE
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCH
KKKQLYNYQRKSKILALDLY
HHHHHHHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]