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The map label for this gene is uxaA [H]

Identifier: 167622352

GI number: 167622352

Start: 483129

End: 484310

Strand: Direct

Name: uxaA [H]

Synonym: Shal_0412

Alternate gene names: 167622352

Gene position: 483129-484310 (Clockwise)

Preceding gene: 167622351

Following gene: 167622353

Centisome position: 9.24

GC content: 49.15

Gene sequence:

>1182_bases
ATGATGAGTAGCTTTATTGGTTTTGGCCGTGCAGATGGCAGTGTGGGTATTCGTAACCATGTATTGATTATGGCGGTGGA
TGAGTGTTGTGACGGCATCGCCCGTGCTATTGCCGACAGTATTGATAATGGAATCGTAGTGACCAACTACAACACCTGTA
TGTATGGTGGTAACGAAGAGATGATCAACACCATGGTACATACGGGCAATAACCCGAACGTGGCCGGGGTACTCGTGTTA
GCAATGGGTTGTGGCAGTATTGATCCTGAAATTGTAGCTGCGCCTATCCGCGTTAGCGGTCGTCCTGCTTTTTCACTGGT
GTGTATGAAGCAACAAGGTACGCGCGCAACCATTACCCAAGGTAAGGCGTTGGCGCAAGAGCTACAGCAAGTTGCACAAG
CCGCGCCTCGAATTGAAACGCCCATTTCTAAGCTAGTGATAGGGGTGAAATGTGGCGGTTCAGATACCAGCTCAGGCATC
GCCTCTAATCCAAGCGTTGGCCGCGCAGTCGATAAGTTAGTCGATCTTGGCGCAACCGCGATTGCCGGTGAATTGATTGA
ATTAGTCGGCTGTGAAACTATTTTACGTCAGCGCGCGGTATCGCCAGAGGTTGCTGACAAACTAGAGCGCTTAATTCATG
AAGAAGAAGCGCGCTGGCACGTAGATGGCGCAGAAGTGGAAACCATGAGCATTGGTAATAGTGTTGGTGGCTTAACCACA
CTAGAGGAAAAGTCTTTTGGTGCGCTGAGTAAAACTGGCACTCGTCCCATTCAAGATGTATTGCAGATAAATCATCTGGT
ACATGAAAAGCCCAAGGCTGCAGGTTTCTACCTATCGGAAGCCACTCATCTATGTGGTAGTGCCGGTATGCATTTTGCCT
CACTGGGCGCGCATCTGATTCTATGGACCACGGGCGGGGCAGGCTTTAATAACCCAATCGTTCCTGTTATTCGTATCAGT
GGTAACCAATATCTGCTAAATGAGGATATTGATATCGACGCTTCTGGTATTATGCGAGCCGAAGAAGGCGTGGAAAGTGT
CGCTGAGCGTATCGTTGCCAAAGTTGGCACTGTTGCTCAAGGCGGGCAGACTAACATTGAAGAGATTGGTTATAGCTACT
GCAGCTTGTACCAGAAAGACCAACGCTTAGAGACTTTGCTGCGCTTTAAGCCCGGCTGCTAA

Upstream 100 bases:

>100_bases
GTGGTGAATTAGCCCATGTGCAAAATGTGCGCAGCCAACGCTTAGATATTCCAGACAATATCATTGAAGAAATTATTAAA
CAGATGCGGATTGAGCAAGC

Downstream 100 bases:

>100_bases
ATGTTTAACCATTAGATTTAGTCATTAATAATGCAATGCCCTTGCTACACATAGTTGTAGCCGGGGCTTATTATCGCAGG
ATGTTATGAATACAACTCAA

Product: D-galactarate dehydratase/Altronate hydrolase domain-containing protein

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MMSSFIGFGRADGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEEMINTMVHTGNNPNVAGVLVL
AMGCGSIDPEIVAAPIRVSGRPAFSLVCMKQQGTRATITQGKALAQELQQVAQAAPRIETPISKLVIGVKCGGSDTSSGI
ASNPSVGRAVDKLVDLGATAIAGELIELVGCETILRQRAVSPEVADKLERLIHEEEARWHVDGAEVETMSIGNSVGGLTT
LEEKSFGALSKTGTRPIQDVLQINHLVHEKPKAAGFYLSEATHLCGSAGMHFASLGAHLILWTTGGAGFNNPIVPVIRIS
GNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVGTVAQGGQTNIEEIGYSYCSLYQKDQRLETLLRFKPGC

Sequences:

>Translated_393_residues
MMSSFIGFGRADGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEEMINTMVHTGNNPNVAGVLVL
AMGCGSIDPEIVAAPIRVSGRPAFSLVCMKQQGTRATITQGKALAQELQQVAQAAPRIETPISKLVIGVKCGGSDTSSGI
ASNPSVGRAVDKLVDLGATAIAGELIELVGCETILRQRAVSPEVADKLERLIHEEEARWHVDGAEVETMSIGNSVGGLTT
LEEKSFGALSKTGTRPIQDVLQINHLVHEKPKAAGFYLSEATHLCGSAGMHFASLGAHLILWTTGGAGFNNPIVPVIRIS
GNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVGTVAQGGQTNIEEIGYSYCSLYQKDQRLETLLRFKPGC
>Mature_393_residues
MMSSFIGFGRADGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEEMINTMVHTGNNPNVAGVLVL
AMGCGSIDPEIVAAPIRVSGRPAFSLVCMKQQGTRATITQGKALAQELQQVAQAAPRIETPISKLVIGVKCGGSDTSSGI
ASNPSVGRAVDKLVDLGATAIAGELIELVGCETILRQRAVSPEVADKLERLIHEEEARWHVDGAEVETMSIGNSVGGLTT
LEEKSFGALSKTGTRPIQDVLQINHLVHEKPKAAGFYLSEATHLCGSAGMHFASLGAHLILWTTGGAGFNNPIVPVIRIS
GNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVGTVAQGGQTNIEEIGYSYCSLYQKDQRLETLLRFKPGC

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=400, Percent_Identity=28.25, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789516, Length=400, Percent_Identity=28.25, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 41578; Mature: 41578

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSFIGFGRADGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEE
CCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHH
MINTMVHTGNNPNVAGVLVLAMGCGSIDPEIVAAPIRVSGRPAFSLVCMKQQGTRATITQ
HHHHHHHCCCCCCHHHHHEEECCCCCCCCCCEEECEEECCCCCEEEEEECCCCCEEEHHH
GKALAQELQQVAQAAPRIETPISKLVIGVKCGGSDTSSGIASNPSVGRAVDKLVDLGATA
HHHHHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHH
IAGELIELVGCETILRQRAVSPEVADKLERLIHEEEARWHVDGAEVETMSIGNSVGGLTT
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCCCCEE
LEEKSFGALSKTGTRPIQDVLQINHLVHEKPKAAGFYLSEATHLCGSAGMHFASLGAHLI
ECCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCHHHHCCCEEE
LWTTGGAGFNNPIVPVIRISGNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVGTVAQ
EEECCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GGQTNIEEIGYSYCSLYQKDQRLETLLRFKPGC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMSSFIGFGRADGSVGIRNHVLIMAVDECCDGIARAIADSIDNGIVVTNYNTCMYGGNEE
CCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHH
MINTMVHTGNNPNVAGVLVLAMGCGSIDPEIVAAPIRVSGRPAFSLVCMKQQGTRATITQ
HHHHHHHCCCCCCHHHHHEEECCCCCCCCCCEEECEEECCCCCEEEEEECCCCCEEEHHH
GKALAQELQQVAQAAPRIETPISKLVIGVKCGGSDTSSGIASNPSVGRAVDKLVDLGATA
HHHHHHHHHHHHHHCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHH
IAGELIELVGCETILRQRAVSPEVADKLERLIHEEEARWHVDGAEVETMSIGNSVGGLTT
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCCCCCEE
LEEKSFGALSKTGTRPIQDVLQINHLVHEKPKAAGFYLSEATHLCGSAGMHFASLGAHLI
ECCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCHHHHCCCEEE
LWTTGGAGFNNPIVPVIRISGNQYLLNEDIDIDASGIMRAEEGVESVAERIVAKVGTVAQ
EEECCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GGQTNIEEIGYSYCSLYQKDQRLETLLRFKPGC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]