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The map label for this gene is pip [H]

Identifier: 167622302

GI number: 167622302

Start: 427328

End: 428260

Strand: Direct

Name: pip [H]

Synonym: Shal_0361

Alternate gene names: 167622302

Gene position: 427328-428260 (Clockwise)

Preceding gene: 167622301

Following gene: 167622303

Centisome position: 8.18

GC content: 48.34

Gene sequence:

>933_bases
GTGCCTATTGCGCAGCCCAAAGCCTTTCGTCGAGTCTGGCTGGATGTCGGCGATACGCATCAGCTGTATGTGGCGCAGTA
TGGTAATCCCGATGGGATCCCGCTGTTGTATCTGCATGGCGGGCCCGGCGCAGGTTGTAGTACTGAAGAGTTAAAGCTAT
TCGATCTGTCTGTTTATCAGGTTATTTTACTTGATCAGCGTGGTGCTGGACGCTCTCGCCCTCGCGGAGAACTCAAACAT
AATAACCTCTCCAGTTTACTGGACGATATCGAGCGAGTGCGCTGCTGGCTTAATATCTCTCAATGGATGCTGGCTGGAGG
CTCATTTGGCGCAACCTTGGCGCTACTGTATTCGGCTTACTATCCAAGCCGGGTGATCTCGCAAGTACTGTGGGGCTTAT
TTATTCCTAACCCCGCGGGCATCGAATGGCTCTACTGTAATAGCGGCGCCGCCCGTTTGTTCAAAGATGAATATAGGGCC
TTTGCTGATGGTGTAGACCCTCAACAGTTAACAACTTTACTCACAAGTTATCGTTCCAGATTAGAAGATGAGTGCCAAGA
CGTTCGTCACTCTGCTACAGAGCGCTGGATCAGTTGGGAGATGGCTTTAGCCTATCCAGGCTTTATGGTCAGTGAGATAA
ATGCGCCCTTCAGTCAGTCTCTAGCAAGCATTGAGCTTTATTATGTAGCTAATGATTACTTTGGTGCATTTGAAAAGCTC
ATCGTTCAATTGCCTTTGATTCAGAGCCAGACCTATGTACTTCAAGGAGAGATGGACTGGGTGTGTCCTTTTAAGGTATT
GCAGAATTTCTTTAAGGGCAGGGCAAGTCAACTGATCGAGGTGACGGAGATTAAAGGTGGGTATCATGCTTTGGCCGATG
TTAAGATGGCGAAAGCGGTAATGAACGCCATACGGGAAATGGCTAAACAATAA

Upstream 100 bases:

>100_bases
ATTCAAAACAGGTTAGCCAAATCGAGCAAACGAGTGAACAAACGCGCGAGCCAGCTCCTGATAAGCAGGCCGAGTCTGCC
GATAGGGATAAGTAGGGCGA

Downstream 100 bases:

>100_bases
AAAAGGAAATTATAGACGCTATGAAAAAACTGATCCTTGTAGGCTTAACTATGGGCTTAACTATGAGCCTAACGGCTTGT
ACTTCAACAGAAAAAACCGC

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPIAQPKAFRRVWLDVGDTHQLYVAQYGNPDGIPLLYLHGGPGAGCSTEELKLFDLSVYQVILLDQRGAGRSRPRGELKH
NNLSSLLDDIERVRCWLNISQWMLAGGSFGATLALLYSAYYPSRVISQVLWGLFIPNPAGIEWLYCNSGAARLFKDEYRA
FADGVDPQQLTTLLTSYRSRLEDECQDVRHSATERWISWEMALAYPGFMVSEINAPFSQSLASIELYYVANDYFGAFEKL
IVQLPLIQSQTYVLQGEMDWVCPFKVLQNFFKGRASQLIEVTEIKGGYHALADVKMAKAVMNAIREMAKQ

Sequences:

>Translated_310_residues
MPIAQPKAFRRVWLDVGDTHQLYVAQYGNPDGIPLLYLHGGPGAGCSTEELKLFDLSVYQVILLDQRGAGRSRPRGELKH
NNLSSLLDDIERVRCWLNISQWMLAGGSFGATLALLYSAYYPSRVISQVLWGLFIPNPAGIEWLYCNSGAARLFKDEYRA
FADGVDPQQLTTLLTSYRSRLEDECQDVRHSATERWISWEMALAYPGFMVSEINAPFSQSLASIELYYVANDYFGAFEKL
IVQLPLIQSQTYVLQGEMDWVCPFKVLQNFFKGRASQLIEVTEIKGGYHALADVKMAKAVMNAIREMAKQ
>Mature_309_residues
PIAQPKAFRRVWLDVGDTHQLYVAQYGNPDGIPLLYLHGGPGAGCSTEELKLFDLSVYQVILLDQRGAGRSRPRGELKHN
NLSSLLDDIERVRCWLNISQWMLAGGSFGATLALLYSAYYPSRVISQVLWGLFIPNPAGIEWLYCNSGAARLFKDEYRAF
ADGVDPQQLTTLLTSYRSRLEDECQDVRHSATERWISWEMALAYPGFMVSEINAPFSQSLASIELYYVANDYFGAFEKLI
VQLPLIQSQTYVLQGEMDWVCPFKVLQNFFKGRASQLIEVTEIKGGYHALADVKMAKAVMNAIREMAKQ

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 34999; Mature: 34867

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAQPKAFRRVWLDVGDTHQLYVAQYGNPDGIPLLYLHGGPGAGCSTEELKLFDLSVYQ
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEHHEEE
VILLDQRGAGRSRPRGELKHNNLSSLLDDIERVRCWLNISQWMLAGGSFGATLALLYSAY
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YPSRVISQVLWGLFIPNPAGIEWLYCNSGAARLFKDEYRAFADGVDPQQLTTLLTSYRSR
CHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LEDECQDVRHSATERWISWEMALAYPGFMVSEINAPFSQSLASIELYYVANDYFGAFEKL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHEEEEEEEECHHHHHHHHH
IVQLPLIQSQTYVLQGEMDWVCPFKVLQNFFKGRASQLIEVTEIKGGYHALADVKMAKAV
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHEEHEECCCCHHHHHHHHHHHHH
MNAIREMAKQ
HHHHHHHHCC
>Mature Secondary Structure 
PIAQPKAFRRVWLDVGDTHQLYVAQYGNPDGIPLLYLHGGPGAGCSTEELKLFDLSVYQ
CCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCEEEEEHHEEE
VILLDQRGAGRSRPRGELKHNNLSSLLDDIERVRCWLNISQWMLAGGSFGATLALLYSAY
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
YPSRVISQVLWGLFIPNPAGIEWLYCNSGAARLFKDEYRAFADGVDPQQLTTLLTSYRSR
CHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LEDECQDVRHSATERWISWEMALAYPGFMVSEINAPFSQSLASIELYYVANDYFGAFEKL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHEEEEEEEECHHHHHHHHH
IVQLPLIQSQTYVLQGEMDWVCPFKVLQNFFKGRASQLIEVTEIKGGYHALADVKMAKAV
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCHHHHHEEHEECCCCHHHHHHHHHHHHH
MNAIREMAKQ
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]