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The map label for this gene is dinF [H]

Identifier: 167622189

GI number: 167622189

Start: 298019

End: 299350

Strand: Reverse

Name: dinF [H]

Synonym: Shal_0248

Alternate gene names: 167622189

Gene position: 299350-298019 (Counterclockwise)

Preceding gene: 167622191

Following gene: 167622187

Centisome position: 5.73

GC content: 47.6

Gene sequence:

>1332_bases
ATGATTGCCTTACTGTTAAACCCACAAAAAAACCGACAACTCTTTGCCCTTGCGCTACCCATGATCCTCTCGAATATCAC
GGTGCCGCTGCTAGGACTCGTCGATACTGCCGTTGTTGGACATCTTAGCAACGCCTATTATTTAGGCGGCGTGGCAGTTG
GGTCAACGATTATAACCTTAATTTTGTGGTTGCTAGGATTTTTACGCATGGCAACCACTGGATTAGTGGCGCAAGCCTAC
GGCGCAAACGACACTGAGCAACAATTTAAATTATTGGTGCAAGCCGCAAGTTTAGCACTACTATTTGGTATTGCCGCCAT
TGCGCTGCAACTCCCCATCCTCAACTTAGCTATGGCGATGTCAGACGCCAGTGTTGAAGTTGAACGCTATTGCCGTGAAT
ATTTCCAAGTCAGGATCTGGTCGACTCCGTTTGCACTAATGAATTTAGTCATGCTCGGCTGGCTGCTTGGACGCCAACAA
CCTAAAGCTGCGATGTGGCAGCTTATTATCGCCAACCTAGTCAATATCGTGTTAGATATCGTCTTCGTTCTTGTTTTAGG
CTGGGGAGTTAAAGGCGCGGCATTCGCCTCTGTCATTGCCGATATTTCAGGCTTCTTAGTGGCGCTGACTATGGTGCGCG
GACAGCTCAATAAACTCGGTAATTTTAAGCTATTTAACGTGGCTAAGCAGCTAACACTGCAAAGCTACGGCAAGTTGATG
GGCCTCAATACCGACATCTTCGTGCGTAGTTTATGTCTACAGCTATCGTTTGCCTTTATGACATTTTACGGCGCAGGCTT
AGGTGACAATACCGTTGCCGCTAATGCCGTATTGCTTAACCTGTTACTGCTTATCTCGTATGCTCTCGACGGCATCGCCT
ATTATGCCGAAGCTGAAGTTGGCCGAGCCTATGGTCAGAAAAATAGTCGCTTAATGCAGGAATCAGTAACGTTAGCCTGG
GCTTGGTCTGCTATCGCCGCGTTAGGCTTTACCCTGTTTTTTGCCTTGGCTGGGTCACACATTATCGCGATGCTAACCAG
CATTACAGAGGTCAGAGAGGTCGCTGAGCAATACATTATCTGGGTGATATTCCTGCCTTTGCTCGCCTTTGGCTCCTACC
TGTTTGATGGTGTTTATATTGGTGCTGCTCAGGGTAAGGTGATGCGTAACAGCATGATCCTATCTACCTTTGGCGTATTT
TTCCCAGTATGGTACTTGCTAGAACCACAGGGTAACTTTGCACTATGGGCAGCCATGAGCTGCTTTATGTTAGCCCGTAG
TGCCTCACTGTCACTGCATTACTGGTTCAAGCTCCGACTGGTATTAAACTGA

Upstream 100 bases:

>100_bases
CATGATGATACTGTAGGATCACCGCCGCGTGAGCCGAAAAACCTGTCAGCGCAAGTAGCGCTAGCAACACGTTTTTAACC
ATAAATATTAGACCTCTAAA

Downstream 100 bases:

>100_bases
TTTAGGCAAAAATAGACATAAAAAACTGACATAAAAAAACGCGACTTAGACTAGAGCTAGAGTCGCGTTATTTTTAATAA
TACCTTGGTATTACTGGTAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MIALLLNPQKNRQLFALALPMILSNITVPLLGLVDTAVVGHLSNAYYLGGVAVGSTIITLILWLLGFLRMATTGLVAQAY
GANDTEQQFKLLVQAASLALLFGIAAIALQLPILNLAMAMSDASVEVERYCREYFQVRIWSTPFALMNLVMLGWLLGRQQ
PKAAMWQLIIANLVNIVLDIVFVLVLGWGVKGAAFASVIADISGFLVALTMVRGQLNKLGNFKLFNVAKQLTLQSYGKLM
GLNTDIFVRSLCLQLSFAFMTFYGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKNSRLMQESVTLAW
AWSAIAALGFTLFFALAGSHIIAMLTSITEVREVAEQYIIWVIFLPLLAFGSYLFDGVYIGAAQGKVMRNSMILSTFGVF
FPVWYLLEPQGNFALWAAMSCFMLARSASLSLHYWFKLRLVLN

Sequences:

>Translated_443_residues
MIALLLNPQKNRQLFALALPMILSNITVPLLGLVDTAVVGHLSNAYYLGGVAVGSTIITLILWLLGFLRMATTGLVAQAY
GANDTEQQFKLLVQAASLALLFGIAAIALQLPILNLAMAMSDASVEVERYCREYFQVRIWSTPFALMNLVMLGWLLGRQQ
PKAAMWQLIIANLVNIVLDIVFVLVLGWGVKGAAFASVIADISGFLVALTMVRGQLNKLGNFKLFNVAKQLTLQSYGKLM
GLNTDIFVRSLCLQLSFAFMTFYGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKNSRLMQESVTLAW
AWSAIAALGFTLFFALAGSHIIAMLTSITEVREVAEQYIIWVIFLPLLAFGSYLFDGVYIGAAQGKVMRNSMILSTFGVF
FPVWYLLEPQGNFALWAAMSCFMLARSASLSLHYWFKLRLVLN
>Mature_443_residues
MIALLLNPQKNRQLFALALPMILSNITVPLLGLVDTAVVGHLSNAYYLGGVAVGSTIITLILWLLGFLRMATTGLVAQAY
GANDTEQQFKLLVQAASLALLFGIAAIALQLPILNLAMAMSDASVEVERYCREYFQVRIWSTPFALMNLVMLGWLLGRQQ
PKAAMWQLIIANLVNIVLDIVFVLVLGWGVKGAAFASVIADISGFLVALTMVRGQLNKLGNFKLFNVAKQLTLQSYGKLM
GLNTDIFVRSLCLQLSFAFMTFYGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEVGRAYGQKNSRLMQESVTLAW
AWSAIAALGFTLFFALAGSHIIAMLTSITEVREVAEQYIIWVIFLPLLAFGSYLFDGVYIGAAQGKVMRNSMILSTFGVF
FPVWYLLEPQGNFALWAAMSCFMLARSASLSLHYWFKLRLVLN

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=425, Percent_Identity=44.9411764705882, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48585; Mature: 48585

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLLNPQKNRQLFALALPMILSNITVPLLGLVDTAVVGHLSNAYYLGGVAVGSTIITL
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHH
ILWLLGFLRMATTGLVAQAYGANDTEQQFKLLVQAASLALLFGIAAIALQLPILNLAMAM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDASVEVERYCREYFQVRIWSTPFALMNLVMLGWLLGRQQPKAAMWQLIIANLVNIVLDI
CCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VFVLVLGWGVKGAAFASVIADISGFLVALTMVRGQLNKLGNFKLFNVAKQLTLQSYGKLM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GLNTDIFVRSLCLQLSFAFMTFYGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRAYGQKNSRLMQESVTLAWAWSAIAALGFTLFFALAGSHIIAMLTSITEVREVAEQYII
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVIFLPLLAFGSYLFDGVYIGAAQGKVMRNSMILSTFGVFFPVWYLLEPQGNFALWAAMS
HHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
CFMLARSASLSLHYWFKLRLVLN
HHHHHHHCCCEEEEEEEEEEEEC
>Mature Secondary Structure
MIALLLNPQKNRQLFALALPMILSNITVPLLGLVDTAVVGHLSNAYYLGGVAVGSTIITL
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHH
ILWLLGFLRMATTGLVAQAYGANDTEQQFKLLVQAASLALLFGIAAIALQLPILNLAMAM
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDASVEVERYCREYFQVRIWSTPFALMNLVMLGWLLGRQQPKAAMWQLIIANLVNIVLDI
CCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VFVLVLGWGVKGAAFASVIADISGFLVALTMVRGQLNKLGNFKLFNVAKQLTLQSYGKLM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GLNTDIFVRSLCLQLSFAFMTFYGAGLGDNTVAANAVLLNLLLLISYALDGIAYYAEAEV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRAYGQKNSRLMQESVTLAWAWSAIAALGFTLFFALAGSHIIAMLTSITEVREVAEQYII
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVIFLPLLAFGSYLFDGVYIGAAQGKVMRNSMILSTFGVFFPVWYLLEPQGNFALWAAMS
HHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
CFMLARSASLSLHYWFKLRLVLN
HHHHHHHCCCEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]