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The map label for this gene is nfuA

Identifier: 167622188

GI number: 167622188

Start: 297350

End: 297928

Strand: Direct

Name: nfuA

Synonym: Shal_0247

Alternate gene names: 167622188

Gene position: 297350-297928 (Clockwise)

Preceding gene: 167622186

Following gene: 167622190

Centisome position: 5.69

GC content: 45.08

Gene sequence:

>579_bases
ATGATTACCATTTCCGAAACAGCTCAGGCGCATTTTGTTAAATTGTTATCAGATCAGCCTGAAGGAACTCACATTCGAGT
ATTTGTTATCAGCCCTGGCACTGCGCAGGCTGAGTGTGGCGTATCGTATTGTCCACCCGATGCGGTTGAGGCTGACGACA
CTGAATTTGAATTCAACGGCTTTAATGCAATGGTTGATGAAAAAAGTGCACCTTTCCTTGAAGAAGCGACTATCGACTTC
GTTACCGATCAGTTGGGTTCTCAGTTAACGCTAAAAGCACCTAATGCTAAGATGCGTAAAGTGTCTGATGATGCTTCATT
GTCAGAGCGCATCGAGTACGTTATCCAGTCTGAAATCAACCCACAGCTTGCTAGCCATGGCGGTAACATCATGCTAGTTG
AAATTACTGAAGAGGGCATTGCTGTACTTCAGTTTGGTGGCGGTTGTAATGGTTGTTCTATGGTTGATGTGACGCTAAAA
GACGGTATCGAGAAGCAACTACTTGAGATGTTCCCTAGTGAGCTAACTGGCGTTAAAGACGTTACAGAGCACCAACACGG
TGAGCACTCTTACCAGTAA

Upstream 100 bases:

>100_bases
TCTGTGAGCCTAGGGGGCTATAAAGGATTGCAGAGTAAGAGTATTATAGGGCTAATTCTTACTAAAACACTCAGGTTTAT
CCCTGACGGAGCATGTTTTC

Downstream 100 bases:

>100_bases
TACCAAGGTATTATTAAAAATAACGCGACTCTAGCTCTAGTCTAAGTCGCGTTTTTTTATGTCAGTTTTTTATGTCTATT
TTTGCCTAAATCAGTTTAAT

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MITISETAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEFEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEINPQLASHGGNIMLVEITEEGIAVLQFGGGCNGCSMVDVTLK
DGIEKQLLEMFPSELTGVKDVTEHQHGEHSYQ

Sequences:

>Translated_192_residues
MITISETAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEFEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEINPQLASHGGNIMLVEITEEGIAVLQFGGGCNGCSMVDVTLK
DGIEKQLLEMFPSELTGVKDVTEHQHGEHSYQ
>Mature_192_residues
MITISETAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEFEFNGFNAMVDEKSAPFLEEATIDF
VTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEINPQLASHGGNIMLVEITEEGIAVLQFGGGCNGCSMVDVTLK
DGIEKQLLEMFPSELTGVKDVTEHQHGEHSYQ

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=191, Percent_Identity=75.3926701570681, Blast_Score=302, Evalue=9e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_SHEHH (B0TNS0)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001672482.1
- ProteinModelPortal:   B0TNS0
- GeneID:   5906709
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_0247
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- ProtClustDB:   PRK11190
- BioCyc:   SHAL458817:SHAL_0247-MONOMER
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 20896; Mature: 20896

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITISETAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEFEFNG
CEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECC
FNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEIN
CEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHHHCCC
PQLASHGGNIMLVEITEEGIAVLQFGGGCNGCSMVDVTLKDGIEKQLLEMFPSELTGVKD
HHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCCCHH
VTEHQHGEHSYQ
HHHHCCCCCCCC
>Mature Secondary Structure
MITISETAQAHFVKLLSDQPEGTHIRVFVISPGTAQAECGVSYCPPDAVEADDTEFEFNG
CEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECC
FNAMVDEKSAPFLEEATIDFVTDQLGSQLTLKAPNAKMRKVSDDASLSERIEYVIQSEIN
CEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCHHHHHHHHHHHCCC
PQLASHGGNIMLVEITEEGIAVLQFGGGCNGCSMVDVTLKDGIEKQLLEMFPSELTGVKD
HHHHHCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCCCHH
VTEHQHGEHSYQ
HHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA