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The map label for this gene is ompR [H]

Identifier: 167622181

GI number: 167622181

Start: 288261

End: 288986

Strand: Reverse

Name: ompR [H]

Synonym: Shal_0240

Alternate gene names: 167622181

Gene position: 288986-288261 (Counterclockwise)

Preceding gene: 167622184

Following gene: 167622180

Centisome position: 5.53

GC content: 49.72

Gene sequence:

>726_bases
ATGGGACAAGAAACCTCAAAAATTCTCGTCGTCGACGATGATATGAGACTACGCGCTTTATTAGAACGCTACTTGATGGA
ACAAGGTTATCAGGTACGTAGTGCTGCCAATGCCGAGCAAATGGACCGTTTATTAGAACGCGAAAACTTCCATCTACTGG
TACTCGATCTTATGCTTCCTGGCGAAGATGGTCTGTCTATCTGCCGTCGCCTGCGCCAAATGGGTAACCCCATCCCTATC
GTGATGCTAACAGCCAAGGGCGATGAAGTGGATAGAATTATCGGTCTAGAACTGGGTGCCGATGACTACTTACCTAAGCC
GTTTAACCCACGAGAGTTGCTCGCCCGAATTAAAGCCGTTATGCGCCGCCAAACACCTGAAGTGCCTGGCGCACCAACCC
TGCAGGAAGAGGAGATCACCTTTGGTGAGTACTCCCTGAATCTGGCCACCCGCGAGATGTACCACGGTGAAGAAAGTATT
TCGCTAACGAGCGGTGAATTTGCGGTACTTAAAGTGCTAGTTAGTCATCCACGGGAACCTCTTTCGCGCGACAAATTAAT
GAATCTTGCTCGTGGCCGCGATTACTCGGCACTCGAGCGTTCGATTGACGTACAAGTTTCGCGCCTGCGTCGACTGATTG
AAAAAGATGCCGCTAACCCACGCTATATCCAAACCGTGTGGGGCTTAGGTTATGTATTTGTACCTGATGGCCAATCACGC
AAATAG

Upstream 100 bases:

>100_bases
TCATTAACATATTAAAACAGCTATATTAGGATGATTCGCATTCAATATCAGCCATTTGCCTAAAGATAAGGGCTGGCCGC
CGAGCAAAAGGACCACAAGC

Downstream 100 bases:

>100_bases
CTAGGCGACGATAACTAAGTGATAATAACTAAGTGGCTATAAACAGACGATGGTGGCAACGCTTTTTGCCACGCAGTTCC
TTCAGCCAAACCGTAATGCT

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQMGNPIPI
VMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPEVPGAPTLQEEEITFGEYSLNLATREMYHGEESI
SLTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
K

Sequences:

>Translated_241_residues
MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQMGNPIPI
VMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPEVPGAPTLQEEEITFGEYSLNLATREMYHGEESI
SLTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
K
>Mature_240_residues
GQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQMGNPIPIV
MLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTPEVPGAPTLQEEEITFGEYSLNLATREMYHGEESIS
LTSGEFAVLKVLVSHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSRK

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=79.1489361702128, Blast_Score=393, Evalue=1e-111,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.8646288209607, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788394, Length=237, Percent_Identity=35.8649789029536, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=39.1489361702128, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790863, Length=239, Percent_Identity=32.6359832635983, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=35.1694915254237, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.0869565217391, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.4675324675325, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=34.4827586206897, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=35.8078602620087, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=30.9012875536481, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=32.0512820512821, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.15859030837, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=31.7073170731707, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27510; Mature: 27379

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLP
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQMGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTPEVPGAPTLQEEEITFGEYSLNLATREMYHGEESISLTSGEFAVLKVLVSHPREP
HHHCCCCCCCCCCCCCCCCEECCEEEHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECCCCCC
K
C
>Mature Secondary Structure 
GQETSKILVVDDDMRLRALLERYLMEQGYQVRSAANAEQMDRLLERENFHLLVLDLMLP
CCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQMGNPIPIVMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTPEVPGAPTLQEEEITFGEYSLNLATREMYHGEESISLTSGEFAVLKVLVSHPREP
HHHCCCCCCCCCCCCCCCCEECCEEEHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDAANPRYIQTVWGLGYVFVPDGQSR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]