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The map label for this gene is ubiC [H]

Identifier: 167622036

GI number: 167622036

Start: 107848

End: 108411

Strand: Reverse

Name: ubiC [H]

Synonym: Shal_0095

Alternate gene names: 167622036

Gene position: 108411-107848 (Counterclockwise)

Preceding gene: 167622039

Following gene: 167622031

Centisome position: 2.07

GC content: 44.86

Gene sequence:

>564_bases
ATGACTGTGACTAGGTTAAGCTTTCCTTATGGTGAATCAATCCAATGGTTTTCGCCAGAACAAATCACCAACTTACCTAC
ACCACCTTTTCAGGAATGGCTATTAAGCACCTGTAGCTTAACGCAAAAATTAAAAAAGCATTGCACTCATTTTGAAGTCA
GAGTTCTTGGAGAAGACACCCTAATTCCACCAGCAAAAGAGGCCTTTGGCTGCGAGAGTATGTGGATTAGAGAGGTGTTA
CTGGTTTTAGACGGCATTCCATGGATCTTCGCGAGGACTCTAATTCCAGGGCAATTACTAGAGAAGAAACAACAAGAGTT
TTTAGGTCTAGGCGTTAGACCCTTAGGCGAACTACTCTATTCCAAAGATGAATTTGTTCCGGGACGGATCGAGGTGGCTC
ACTTTGAAGCGTGCAGCAAAATCGCAAAACTCGCGGGATCACTACAACAAGATGTGAGTCAGGAGTTGTGGGGACGTCGT
CGCTATTTTCAATATGAAACCGAGCAATTGGTCGTTAGCGAGGTTTTCTTACCCGCTGCACAAGAAGCCATCGCGAAGCT
CTAG

Upstream 100 bases:

>100_bases
TCCTGCATGCCAAGCTAATCACTCTGTGTCGACAACCTCTACCTGCAACTGCACTGACATGCTAGACTGCTTCGGTTTGC
TGCATTGTACCGAGAATTAG

Downstream 100 bases:

>100_bases
CTGCATAGCAAAAAATAAAAAACGCCCTAACTAGGGCACTTCATGCGGCGAGTTATGTCTATGAGGCTTGACGCCGATAT
AAGCTGAATAGGCCGAGCAT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MTVTRLSFPYGESIQWFSPEQITNLPTPPFQEWLLSTCSLTQKLKKHCTHFEVRVLGEDTLIPPAKEAFGCESMWIREVL
LVLDGIPWIFARTLIPGQLLEKKQQEFLGLGVRPLGELLYSKDEFVPGRIEVAHFEACSKIAKLAGSLQQDVSQELWGRR
RYFQYETEQLVVSEVFLPAAQEAIAKL

Sequences:

>Translated_187_residues
MTVTRLSFPYGESIQWFSPEQITNLPTPPFQEWLLSTCSLTQKLKKHCTHFEVRVLGEDTLIPPAKEAFGCESMWIREVL
LVLDGIPWIFARTLIPGQLLEKKQQEFLGLGVRPLGELLYSKDEFVPGRIEVAHFEACSKIAKLAGSLQQDVSQELWGRR
RYFQYETEQLVVSEVFLPAAQEAIAKL
>Mature_186_residues
TVTRLSFPYGESIQWFSPEQITNLPTPPFQEWLLSTCSLTQKLKKHCTHFEVRVLGEDTLIPPAKEAFGCESMWIREVLL
VLDGIPWIFARTLIPGQLLEKKQQEFLGLGVRPLGELLYSKDEFVPGRIEVAHFEACSKIAKLAGSLQQDVSQELWGRRR
YFQYETEQLVVSEVFLPAAQEAIAKL

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=158, Percent_Identity=29.746835443038, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 21382; Mature: 21251

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTRLSFPYGESIQWFSPEQITNLPTPPFQEWLLSTCSLTQKLKKHCTHFEVRVLGEDT
CCEEECCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LIPPAKEAFGCESMWIREVLLVLDGIPWIFARTLIPGQLLEKKQQEFLGLGVRPLGELLY
CCCCCHHHHCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHH
SKDEFVPGRIEVAHFEACSKIAKLAGSLQQDVSQELWGRRRYFQYETEQLVVSEVFLPAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAIAKL
HHHHHCC
>Mature Secondary Structure 
TVTRLSFPYGESIQWFSPEQITNLPTPPFQEWLLSTCSLTQKLKKHCTHFEVRVLGEDT
CEEECCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LIPPAKEAFGCESMWIREVLLVLDGIPWIFARTLIPGQLLEKKQQEFLGLGVRPLGELLY
CCCCCHHHHCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHH
SKDEFVPGRIEVAHFEACSKIAKLAGSLQQDVSQELWGRRRYFQYETEQLVVSEVFLPAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAIAKL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA