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The map label for this gene is yiaY [H]

Identifier: 167622024

GI number: 167622024

Start: 93176

End: 94327

Strand: Reverse

Name: yiaY [H]

Synonym: Shal_0083

Alternate gene names: 167622024

Gene position: 94327-93176 (Counterclockwise)

Preceding gene: 167622025

Following gene: 167622023

Centisome position: 1.8

GC content: 44.1

Gene sequence:

>1152_bases
ATGAGCAGCGTATTTTACATGCCTCCAATGACCCTCATGGGCCAAAACGCAATACAGTCACTCGGTTCTGAACTTACAAG
CAAAGAACTCACAAAAGCGCTTATCGTGACAGACAGCGTGCTAGTTGAAATCGGACTCGTTAATCGTCTAACTGATGAGC
TTAAGGCACACAATATTGACTTTGCGATTTATGACGGTGTTAAGCCAAATCCAACAGAGAAAAATATCGAAGACGGTCTT
GCTTTATTGAATCAAGAAAACTGTGACTTCGTTATTTCATTTGGTGGCGGCTCATCACACGATGCAGCAAAAGGTGTCGC
CTTAGTTGCCGCTAATGGTGGTCATATTCGTGACTATTCAAAAGGTGTGCACACATCTAAGAAACCACAACTTCCACTAG
TCACAATTAACACGACTGCTGGTACGGCTTCTGAAATGACAGTATTTGCCATCATCACTAACGAAGCTGACGAAACTAAA
TACCCTGTTGTAGATAAGCATTTTACACCGATCATTGCTGTTAACGATTCTGAGCTCATGGTTGCTATGCCTAAGTTCTT
AACTGCAGCCACAGGTATGGATGCGTTAACACACGCTATTGAAGCCTATGTTTCTACTGCGGCAACACCTATCACCGATG
CATCGGCAATCAAGGCGATTGAGTTAATCTCACAAAACTTAACCACCGCAGTTGAAAATGGTGAAGACCGCAAAGCACGT
GATGCAATGCAATACGGTGAATACCTTGCGGGTATGGCGTTTTCTAACGCTTCACTAGGTTATGTTCACTCTATGGCGCA
TCAGTTAGGCGGAGTTTACGACTTAGTACACGGTCTATGTAACGCAATTCTTCTTCCAGAAGTCTCACGCTTCAACGCTG
TAGCAACACCAGCACGCTTTGTTGATATCGCTAAAGCTATGGGTGTTGATGTGTCAGCAATGACACAGGCTCAAGCTATT
GAAGCGGGTATAGAGGCAATTGAAGCACTATCTCGTCAAGTCGGCACGGCACAACGTCTAAGTGACTTAGGTGTTACTGA
AGAGAAACTCGCATTCATGGCGCAAAACGCGCTAAACGATGCTTGTTCTTTAACTAACCCACGCAAAGCGAGTCTTGAAG
AAATTATCACTATCTTTAGAGCGCGTTTGTAA

Upstream 100 bases:

>100_bases
GCAGGCAAGTCACCCTCAAATATTCATAGATCATTTTTATATTCTCAACCCATTTAATTTTTCATTTAAAACTTTGATTT
ATAAACTTTAGGAAAACATT

Downstream 100 bases:

>100_bases
TCCGATCTTAAAGCAATCAATACGTTAGCTCACAAGTAACAATGAAGGGAAATCTGCATTTCCCCTCATTCATTATTCTA
GGATCCCTATGACAACCCTA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSSVFYMPPMTLMGQNAIQSLGSELTSKELTKALIVTDSVLVEIGLVNRLTDELKAHNIDFAIYDGVKPNPTEKNIEDGL
ALLNQENCDFVISFGGGSSHDAAKGVALVAANGGHIRDYSKGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETK
YPVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAIEAYVSTAATPITDASAIKAIELISQNLTTAVENGEDRKAR
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPARFVDIAKAMGVDVSAMTQAQAI
EAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALNDACSLTNPRKASLEEIITIFRARL

Sequences:

>Translated_383_residues
MSSVFYMPPMTLMGQNAIQSLGSELTSKELTKALIVTDSVLVEIGLVNRLTDELKAHNIDFAIYDGVKPNPTEKNIEDGL
ALLNQENCDFVISFGGGSSHDAAKGVALVAANGGHIRDYSKGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETK
YPVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAIEAYVSTAATPITDASAIKAIELISQNLTTAVENGEDRKAR
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPARFVDIAKAMGVDVSAMTQAQAI
EAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALNDACSLTNPRKASLEEIITIFRARL
>Mature_382_residues
SSVFYMPPMTLMGQNAIQSLGSELTSKELTKALIVTDSVLVEIGLVNRLTDELKAHNIDFAIYDGVKPNPTEKNIEDGLA
LLNQENCDFVISFGGGSSHDAAKGVALVAANGGHIRDYSKGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETKY
PVVDKHFTPIIAVNDSELMVAMPKFLTAATGMDALTHAIEAYVSTAATPITDASAIKAIELISQNLTTAVENGEDRKARD
AMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPARFVDIAKAMGVDVSAMTQAQAIE
AGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALNDACSLTNPRKASLEEIITIFRARL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=412, Percent_Identity=24.7572815533981, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI48994951, Length=382, Percent_Identity=56.282722513089, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1789163, Length=370, Percent_Identity=43.5135135135135, Blast_Score=312, Evalue=2e-86,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=38.3597883597884, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1787493, Length=380, Percent_Identity=32.6315789473684, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1789386, Length=348, Percent_Identity=23.2758620689655, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537053, Length=413, Percent_Identity=23.4866828087167, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321181, Length=384, Percent_Identity=48.6979166666667, Blast_Score=365, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24657991, Length=419, Percent_Identity=24.582338902148, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40809; Mature: 40678

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVFYMPPMTLMGQNAIQSLGSELTSKELTKALIVTDSVLVEIGLVNRLTDELKAHNID
CCCEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FAIYDGVKPNPTEKNIEDGLALLNQENCDFVISFGGGSSHDAAKGVALVAANGGHIRDYS
EEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHH
KGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETKYPVVDKHFTPIIAVNDSELM
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCE
VAMPKFLTAATGMDALTHAIEAYVSTAATPITDASAIKAIELISQNLTTAVENGEDRKAR
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPARF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHH
VDIAKAMGVDVSAMTQAQAIEAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALND
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHH
ACSLTNPRKASLEEIITIFRARL
HHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSVFYMPPMTLMGQNAIQSLGSELTSKELTKALIVTDSVLVEIGLVNRLTDELKAHNID
CCEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FAIYDGVKPNPTEKNIEDGLALLNQENCDFVISFGGGSSHDAAKGVALVAANGGHIRDYS
EEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHH
KGVHTSKKPQLPLVTINTTAGTASEMTVFAIITNEADETKYPVVDKHFTPIIAVNDSELM
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCE
VAMPKFLTAATGMDALTHAIEAYVSTAATPITDASAIKAIELISQNLTTAVENGEDRKAR
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
DAMQYGEYLAGMAFSNASLGYVHSMAHQLGGVYDLVHGLCNAILLPEVSRFNAVATPARF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHH
VDIAKAMGVDVSAMTQAQAIEAGIEAIEALSRQVGTAQRLSDLGVTEEKLAFMAQNALND
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHH
ACSLTNPRKASLEEIITIFRARL
HHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]