Click here to switch to the map view.

The map label for this gene is tktB [C]

Identifier: 167040553

GI number: 167040553

Start: 1935029

End: 1935874

Strand: Reverse

Name: tktB [C]

Synonym: Teth514_1924

Alternate gene names: 167040553

Gene position: 1935874-1935029 (Counterclockwise)

Preceding gene: 167040554

Following gene: 167040552

Centisome position: 78.78

GC content: 34.4

Gene sequence:

>846_bases
TTGAGCATTACTTTTGAAGAAATTGATTTGATAAAACAGACTGCTGATTTGATAAGAAAAGATTGCATTTGGATGAGTAC
CCGGGCAGGTACAGGACACCTTGGACCAGCACTTTCATTAGCAGAAATTTTAGCTACTTTATATAAAAGTGTATTAAAGG
TAGATCCACAGAATCCAAAATGGCCTGATAGAGATAGGCTAATACTTAGTAAAGGCCATGGATGTTTGGCACTTTATTCT
ATACTTTCACAAATGGGGTTTTTTGAAAGAAAATTATTAGGAGATTTTTGTACTAAATATGATACTATGCTTCCGGGTCA
CCCAGAAATTAAGCTTCCTGGTGTAGAAGCTAATACTGGTTCTTTAGGACATGGAATAGCTCTAGGAGTAGGAATGGCTT
TAGCAGCCAGAATGGACAAAAAAGAATACAGAGTTTTTGTAATAACTGGAGATGGAGAATTACAGGAAGGAAGTAACTGG
GAAGCAGCCATGACTGCTGCTTATTATGGACTAGATAATTTAATTGTAATAGTAGATAGAAATATGTTGCAATTAGGAGA
TTTTACAGAAAATATAACCCGGTTAGAACCTTTAGCTGAAAAATGGAAAAGTTTTGGATGGGGCGTAGAAATAATAGATG
GTCACGATATAGAAAAATTACTTACAGCTTTTAATAAAATTCCGTTTGTTAAAGGTCAGCCTTCTGTTATTATTGCTAAT
ACTGTAAAAGGAAAGGGCTTAAAAATTGCTGAAAATAAGGTTGATTGGCACTATAAAGTTCTTTCATATGAACAATACGA
GGAATTAAAAAATGAAATGTCATTGGAGGAGCTTTATCATGAGTGA

Upstream 100 bases:

>100_bases
ATTACTACTTATACTCAATTTTCAAAAGCTGTTATAGACCTTGAAAATTATGTAAGGAGTTTATTTTAAAAAATAAAAAT
AACTGAAGGAGTTGATTCTT

Downstream 100 bases:

>100_bases
ATTAAAGAAGTCAACCAGAACATCATTTGCTGAGGCAATTGTTGAGCTGGGAGAGAAAAATCCAGATGTTGTAACTGTTG
CAGCGGATTCAGCATCACGA

Product: transketolase domain-containing protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSITFEEIDLIKQTADLIRKDCIWMSTRAGTGHLGPALSLAEILATLYKSVLKVDPQNPKWPDRDRLILSKGHGCLALYS
ILSQMGFFERKLLGDFCTKYDTMLPGHPEIKLPGVEANTGSLGHGIALGVGMALAARMDKKEYRVFVITGDGELQEGSNW
EAAMTAAYYGLDNLIVIVDRNMLQLGDFTENITRLEPLAEKWKSFGWGVEIIDGHDIEKLLTAFNKIPFVKGQPSVIIAN
TVKGKGLKIAENKVDWHYKVLSYEQYEELKNEMSLEELYHE

Sequences:

>Translated_281_residues
MSITFEEIDLIKQTADLIRKDCIWMSTRAGTGHLGPALSLAEILATLYKSVLKVDPQNPKWPDRDRLILSKGHGCLALYS
ILSQMGFFERKLLGDFCTKYDTMLPGHPEIKLPGVEANTGSLGHGIALGVGMALAARMDKKEYRVFVITGDGELQEGSNW
EAAMTAAYYGLDNLIVIVDRNMLQLGDFTENITRLEPLAEKWKSFGWGVEIIDGHDIEKLLTAFNKIPFVKGQPSVIIAN
TVKGKGLKIAENKVDWHYKVLSYEQYEELKNEMSLEELYHE
>Mature_280_residues
SITFEEIDLIKQTADLIRKDCIWMSTRAGTGHLGPALSLAEILATLYKSVLKVDPQNPKWPDRDRLILSKGHGCLALYSI
LSQMGFFERKLLGDFCTKYDTMLPGHPEIKLPGVEANTGSLGHGIALGVGMALAARMDKKEYRVFVITGDGELQEGSNWE
AAMTAAYYGLDNLIVIVDRNMLQLGDFTENITRLEPLAEKWKSFGWGVEIIDGHDIEKLLTAFNKIPFVKGQPSVIIANT
VKGKGLKIAENKVDWHYKVLSYEQYEELKNEMSLEELYHE

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=270, Percent_Identity=38.5185185185185, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4507521, Length=270, Percent_Identity=38.5185185185185, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI133778974, Length=268, Percent_Identity=36.1940298507463, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI225637459, Length=263, Percent_Identity=27.7566539923954, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI225637461, Length=229, Percent_Identity=29.2576419213974, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI225637463, Length=227, Percent_Identity=28.6343612334802, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1788808, Length=267, Percent_Identity=35.2059925093633, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI48994911, Length=264, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17539652, Length=260, Percent_Identity=37.6923076923077, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6325331, Length=255, Percent_Identity=34.9019607843137, Blast_Score=129, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319593, Length=280, Percent_Identity=32.1428571428571, Blast_Score=126, Evalue=3e-30,
Organism=Drosophila melanogaster, GI45551847, Length=262, Percent_Identity=37.0229007633588, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI45550715, Length=262, Percent_Identity=37.0229007633588, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24666278, Length=262, Percent_Identity=36.2595419847328, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24645119, Length=229, Percent_Identity=37.9912663755458, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 31524; Mature: 31393

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITFEEIDLIKQTADLIRKDCIWMSTRAGTGHLGPALSLAEILATLYKSVLKVDPQNPK
CCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
WPDRDRLILSKGHGCLALYSILSQMGFFERKLLGDFCTKYDTMLPGHPEIKLPGVEANTG
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
SLGHGIALGVGMALAARMDKKEYRVFVITGDGELQEGSNWEAAMTAAYYGLDNLIVIVDR
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
NMLQLGDFTENITRLEPLAEKWKSFGWGVEIIDGHDIEKLLTAFNKIPFVKGQPSVIIAN
CCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEE
TVKGKGLKIAENKVDWHYKVLSYEQYEELKNEMSLEELYHE
CCCCCCEEEECCCCCEEEEEECHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
SITFEEIDLIKQTADLIRKDCIWMSTRAGTGHLGPALSLAEILATLYKSVLKVDPQNPK
CCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
WPDRDRLILSKGHGCLALYSILSQMGFFERKLLGDFCTKYDTMLPGHPEIKLPGVEANTG
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC
SLGHGIALGVGMALAARMDKKEYRVFVITGDGELQEGSNWEAAMTAAYYGLDNLIVIVDR
CCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
NMLQLGDFTENITRLEPLAEKWKSFGWGVEIIDGHDIEKLLTAFNKIPFVKGQPSVIIAN
CCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEE
TVKGKGLKIAENKVDWHYKVLSYEQYEELKNEMSLEELYHE
CCCCCCEEEECCCCCEEEEEECHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]