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The map label for this gene is spoIVB [H]

Identifier: 167040183

GI number: 167040183

Start: 1568347

End: 1569660

Strand: Direct

Name: spoIVB [H]

Synonym: Teth514_1545

Alternate gene names: 167040183

Gene position: 1568347-1569660 (Clockwise)

Preceding gene: 167040182

Following gene: 167040184

Centisome position: 63.83

GC content: 30.14

Gene sequence:

>1314_bases
ATGACAAAAAATACAGTAAAATTGTTACTTTTTATATTCTTAAGCTTTTTTTTAGTATTTGCAAATTATTTTACTCCTAT
ACAAGATATAGCGAAAACTCCCTCAAGTTTTAAATTTTTTCAAGGAGAAAAAGTTAATTATAACTTTAATATACCAATAA
AAGTAAGTTTTCAAGCTGATAAAAAAGGTTTTTTAAAAATTAATGATACAGAAGATAAAAATGTTTTAAATTTGAAAGAA
CCTATTACTATAGAAGCAGTAAACACTGGCACAGTAAATTTGGATTTTAAGCTCTTTGGAATATTTCCTATAAAGCATAT
CAGTGTTGACATCGTTCCGACCATAAAAGTAGTACCGGGCGGCCAAGCGATAGGGGTTAATTTAAATACCAAGGGAGCAT
TAGTAGTAGGCTATTCAGATATAATGGGTGAGGACGGTAAAATTTATAGTCCTTATAAGCAAGGAAAAATACAGATAGGA
GATATAATATTAGAAGTCAACGGCAAAGAAATAAAGCAAGCAGAAGATATCACTAACATTGCAAATGAATTACAAGGGAA
AGCTTTAAAATTAAAAATAAACAGAAAAAATAATATTTTTTATACTACTATTTATCCTATAAAGTCAAAAGAGGATAAAC
AATACAGAATAGGTCTTTGGGTGAGAGACCACACTGCTGGTATAGGTACTTTAACCTTTTATTATCCTGCTAGTAAGATG
TATGGAGCTTTAGGTCATGCTATAACTGATATAGATACTGGTCACATGTTATCAGTAGAAAATGGAGAAATTATGAATTC
TCGAATTACTTCTATTGACCATGGAAGAAGAAGTAAACCCGGGGAATTAAAAGGGATTTTTTTAGAAGAAGTTGATACAA
TAGGTAATATATTAAAAAACACTGAATTTGGAATTTACGGGAATATGTATGAAGACTTTAAGAACGATTTGTATGGAGAA
ATTCCTATAGCATATCAAAGCCAAATAAAAGAAGGGCCAGCTAAAATATTGGCTACCATTGATAATACAGGTATACAGCA
ATTTGATATTGAAATTATCAAAAAAGTGTATCAAGAAACTCCTAGCCCTAAAAGTATGATAATTAAAATTGTTGACAAGA
ATTTATTAAAAAAGACTGGAGGCATAATACAGGGTATGAGTGGTAGTCCTATTATACAAGATGGAAAACTGGTAGGAGCA
GTTACTCATGTTTTTGTGAATGACCCTACAAAAGGATATGCTGTTTATGCAGAATGGATGATTAATGAAATGAATACGCT
GCTTAATAATAAGCAGGTTTTTACAAATAACTAA

Upstream 100 bases:

>100_bases
CTTCCTTTTACTATCGGATAATATATTGACAGTATATAAAGCTTTAAAAAAGGTTAAGTTAATTTTAGATTAAATAAGCA
GCAAAAAAGGAAGTGAGAAG

Downstream 100 bases:

>100_bases
AAATTTTTAAGGGAAAAAGAAGGAAATTCAAATATTATGTAGAATAAATATTATATACTAATATTAGCAATGGGAGGTTA
AATAATTGGTTAAGAAGATT

Product: peptidase S55, SpoIVB

Products: NA

Alternate protein names: Sporulation factor IV B protease; Stage IV sporulation protein B [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTKNTVKLLLFIFLSFFLVFANYFTPIQDIAKTPSSFKFFQGEKVNYNFNIPIKVSFQADKKGFLKINDTEDKNVLNLKE
PITIEAVNTGTVNLDFKLFGIFPIKHISVDIVPTIKVVPGGQAIGVNLNTKGALVVGYSDIMGEDGKIYSPYKQGKIQIG
DIILEVNGKEIKQAEDITNIANELQGKALKLKINRKNNIFYTTIYPIKSKEDKQYRIGLWVRDHTAGIGTLTFYYPASKM
YGALGHAITDIDTGHMLSVENGEIMNSRITSIDHGRRSKPGELKGIFLEEVDTIGNILKNTEFGIYGNMYEDFKNDLYGE
IPIAYQSQIKEGPAKILATIDNTGIQQFDIEIIKKVYQETPSPKSMIIKIVDKNLLKKTGGIIQGMSGSPIIQDGKLVGA
VTHVFVNDPTKGYAVYAEWMINEMNTLLNNKQVFTNN

Sequences:

>Translated_437_residues
MTKNTVKLLLFIFLSFFLVFANYFTPIQDIAKTPSSFKFFQGEKVNYNFNIPIKVSFQADKKGFLKINDTEDKNVLNLKE
PITIEAVNTGTVNLDFKLFGIFPIKHISVDIVPTIKVVPGGQAIGVNLNTKGALVVGYSDIMGEDGKIYSPYKQGKIQIG
DIILEVNGKEIKQAEDITNIANELQGKALKLKINRKNNIFYTTIYPIKSKEDKQYRIGLWVRDHTAGIGTLTFYYPASKM
YGALGHAITDIDTGHMLSVENGEIMNSRITSIDHGRRSKPGELKGIFLEEVDTIGNILKNTEFGIYGNMYEDFKNDLYGE
IPIAYQSQIKEGPAKILATIDNTGIQQFDIEIIKKVYQETPSPKSMIIKIVDKNLLKKTGGIIQGMSGSPIIQDGKLVGA
VTHVFVNDPTKGYAVYAEWMINEMNTLLNNKQVFTNN
>Mature_436_residues
TKNTVKLLLFIFLSFFLVFANYFTPIQDIAKTPSSFKFFQGEKVNYNFNIPIKVSFQADKKGFLKINDTEDKNVLNLKEP
ITIEAVNTGTVNLDFKLFGIFPIKHISVDIVPTIKVVPGGQAIGVNLNTKGALVVGYSDIMGEDGKIYSPYKQGKIQIGD
IILEVNGKEIKQAEDITNIANELQGKALKLKINRKNNIFYTTIYPIKSKEDKQYRIGLWVRDHTAGIGTLTFYYPASKMY
GALGHAITDIDTGHMLSVENGEIMNSRITSIDHGRRSKPGELKGIFLEEVDTIGNILKNTEFGIYGNMYEDFKNDLYGEI
PIAYQSQIKEGPAKILATIDNTGIQQFDIEIIKKVYQETPSPKSMIIKIVDKNLLKKTGGIIQGMSGSPIIQDGKLVGAV
THVFVNDPTKGYAVYAEWMINEMNTLLNNKQVFTNN

Specific function: Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by c

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Forespore intermembrane space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase S55 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR014219
- InterPro:   IPR008763 [H]

Pfam domain/function: PF00595 PDZ; PF05580 Peptidase_S55 [H]

EC number: =3.4.21.116 [H]

Molecular weight: Translated: 48850; Mature: 48719

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNTVKLLLFIFLSFFLVFANYFTPIQDIAKTPSSFKFFQGEKVNYNFNIPIKVSFQAD
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEECCCEEEEEECCEEEEEEECC
KKGFLKINDTEDKNVLNLKEPITIEAVNTGTVNLDFKLFGIFPIKHISVDIVPTIKVVPG
CCCCEEEECCCCCCEEECCCCEEEEEEECCEEEEEEEEEEEEEEEEEEEEEEEEEEEECC
GQAIGVNLNTKGALVVGYSDIMGEDGKIYSPYKQGKIQIGDIILEVNGKEIKQAEDITNI
CEEEEEEECCCCEEEEEEHHHCCCCCCEECCHHCCCEEEEEEEEEECCCHHHHHHHHHHH
ANELQGKALKLKINRKNNIFYTTIYPIKSKEDKQYRIGLWVRDHTAGIGTLTFYYPASKM
HHHHCCCEEEEEEECCCCEEEEEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECHHHH
YGALGHAITDIDTGHMLSVENGEIMNSRITSIDHGRRSKPGELKGIFLEEVDTIGNILKN
HHHHHHHHEECCCCCEEEECCCCEEHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHC
TEFGIYGNMYEDFKNDLYGEIPIAYQSQIKEGPAKILATIDNTGIQQFDIEIIKKVYQET
CCCCEECCHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
PSPKSMIIKIVDKNLLKKTGGIIQGMSGSPIIQDGKLVGAVTHVFVNDPTKGYAVYAEWM
CCCHHHEEEEHHHHHHHHCCCEEECCCCCCEEECCEEEEEEEEEEECCCCCCEEEEEHHH
INEMNTLLNNKQVFTNN
HHHHHHHHCCCEEEECC
>Mature Secondary Structure 
TKNTVKLLLFIFLSFFLVFANYFTPIQDIAKTPSSFKFFQGEKVNYNFNIPIKVSFQAD
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCEEECCCEEEEEECCEEEEEEECC
KKGFLKINDTEDKNVLNLKEPITIEAVNTGTVNLDFKLFGIFPIKHISVDIVPTIKVVPG
CCCCEEEECCCCCCEEECCCCEEEEEEECCEEEEEEEEEEEEEEEEEEEEEEEEEEEECC
GQAIGVNLNTKGALVVGYSDIMGEDGKIYSPYKQGKIQIGDIILEVNGKEIKQAEDITNI
CEEEEEEECCCCEEEEEEHHHCCCCCCEECCHHCCCEEEEEEEEEECCCHHHHHHHHHHH
ANELQGKALKLKINRKNNIFYTTIYPIKSKEDKQYRIGLWVRDHTAGIGTLTFYYPASKM
HHHHCCCEEEEEEECCCCEEEEEEEEECCCCCCEEEEEEEEEECCCCEEEEEEEECHHHH
YGALGHAITDIDTGHMLSVENGEIMNSRITSIDHGRRSKPGELKGIFLEEVDTIGNILKN
HHHHHHHHEECCCCCEEEECCCCEEHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHC
TEFGIYGNMYEDFKNDLYGEIPIAYQSQIKEGPAKILATIDNTGIQQFDIEIIKKVYQET
CCCCEECCHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHC
PSPKSMIIKIVDKNLLKKTGGIIQGMSGSPIIQDGKLVGAVTHVFVNDPTKGYAVYAEWM
CCCHHHEEEEHHHHHHHHCCCEEECCCCCCEEECCEEEEEEEEEEECCCCCCEEEEEHHH
INEMNTLLNNKQVFTNN
HHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2106508; 8969508; 9384377; 11741860 [H]