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The map label for this gene is pilC [H]

Identifier: 167040144

GI number: 167040144

Start: 1538369

End: 1539580

Strand: Direct

Name: pilC [H]

Synonym: Teth514_1506

Alternate gene names: 167040144

Gene position: 1538369-1539580 (Clockwise)

Preceding gene: 167040143

Following gene: 167040145

Centisome position: 62.61

GC content: 36.06

Gene sequence:

>1212_bases
ATGCCGTTGTATGCTTATAGGGCAAGGGATATGGGAGGAAATCTCGTTACAGGGACTTTGGAAGTTGACTCAAAATCTCA
GTGTATTGACATTTTAAAACAGAGAAATTATTATATAATCGACATACAAGAAGAGATAGTCAAACAAGACATACTCGATT
TTAGTTCTTTTAAAAAGGTCAAAGTAAAAGATATTGCGGTCTTCTGTCGGCAGTTTGCCACTCTGATAAATGCAGGGATT
CCTATAGTGACCTCTTTGGTTACTATGAGAGAACAAGTGGAGAATAAAAGACTGAAAAATGCTTTGAGAGAGGTGTACGA
AGAAGTTCAAAAAGGAAGGACTCTTTCTGATGCTATGAAAAGGCACAGTGATGTTTTTCCTATGCTTTTATATAATATGG
TGGAAGTGGGGGAAGTAAGCGGTACTTTAGATAAAGTGATGAATGAAATGGCAGAACACTATGAAAAAGAGAATGAATTA
AATCAGAAAATAAAGTCTGCCCTTACATATCCTGTAATTGTGTCAATCGTAGCGATTTTGGTGGTTATATTTCTCTTGAC
AAATGTTTTGCCTATTTTTGTGGGGATGTTTGAAAATGCAGGTGTACAGCTGCCACTGCCTACAAGGATTCTCCTCGCTA
TAAGCGGTTCTATATCTAAATATTGGTATTTTTACATAGGAGTAATTTTGGTGATTTCTTATTCGATTTCGAGTTTTTTA
AAGACACCTCAAGGAAGGTGCATTTATGACAGAATGCTTTTAAACATGCCAATCTTTGCCCCTTTAAACAAAAAGATTTT
AATTTCCAGGTTTACAAGGACTTTAGGAACATTGATAAGTGCTGGTGTACCGCTTATGAAGGCAATGGAAGTAGTAGAAA
AAGTTGTGGGTAATACAGTAGTAGCAGAGGGACTTAAAAAAGCGCAAGACGATATAAAAAAAGGCTTACCCCTTTCAGAA
CCTCTAAAAAGAATTGGCATTTTCCCGCCAATGGTGATTCAGATGATAGGTATTGGTGAAAGTTCAGGTTCATTGGACAG
CATATTAAATAAAACTGCTGATTTTTATGACGGAGAAGTGGATACAGCCGTGTCACAAATGACAACTCTATTAGAACCAT
TAATAATTGTTATGCTGGCAACAGTAGTGGGATTTATAGTTATCTCAATAATTATGCCACTCTTTGAATTATACAATTTT
ATAGGCCAGTGA

Upstream 100 bases:

>100_bases
ATTTTACATCTGTTAAAAAGAGGAGTTATATCATTAGAGGATGCTTTGACATATTGCGTAGACCAAGAGAATTTTTCTCG
CATGATATAGAGGTGATTAT

Downstream 100 bases:

>100_bases
TATTGGGAAAGGGGGTGAAAAAGGATGGAATGGTTTGTAAAAGCATTAAACAAGGATGAAAGAGGTTTTACATTAATTGA
ATTGATTGTTGTCATTGCAA

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPLYAYRARDMGGNLVTGTLEVDSKSQCIDILKQRNYYIIDIQEEIVKQDILDFSSFKKVKVKDIAVFCRQFATLINAGI
PIVTSLVTMREQVENKRLKNALREVYEEVQKGRTLSDAMKRHSDVFPMLLYNMVEVGEVSGTLDKVMNEMAEHYEKENEL
NQKIKSALTYPVIVSIVAILVVIFLLTNVLPIFVGMFENAGVQLPLPTRILLAISGSISKYWYFYIGVILVISYSISSFL
KTPQGRCIYDRMLLNMPIFAPLNKKILISRFTRTLGTLISAGVPLMKAMEVVEKVVGNTVVAEGLKKAQDDIKKGLPLSE
PLKRIGIFPPMVIQMIGIGESSGSLDSILNKTADFYDGEVDTAVSQMTTLLEPLIIVMLATVVGFIVISIIMPLFELYNF
IGQ

Sequences:

>Translated_403_residues
MPLYAYRARDMGGNLVTGTLEVDSKSQCIDILKQRNYYIIDIQEEIVKQDILDFSSFKKVKVKDIAVFCRQFATLINAGI
PIVTSLVTMREQVENKRLKNALREVYEEVQKGRTLSDAMKRHSDVFPMLLYNMVEVGEVSGTLDKVMNEMAEHYEKENEL
NQKIKSALTYPVIVSIVAILVVIFLLTNVLPIFVGMFENAGVQLPLPTRILLAISGSISKYWYFYIGVILVISYSISSFL
KTPQGRCIYDRMLLNMPIFAPLNKKILISRFTRTLGTLISAGVPLMKAMEVVEKVVGNTVVAEGLKKAQDDIKKGLPLSE
PLKRIGIFPPMVIQMIGIGESSGSLDSILNKTADFYDGEVDTAVSQMTTLLEPLIIVMLATVVGFIVISIIMPLFELYNF
IGQ
>Mature_402_residues
PLYAYRARDMGGNLVTGTLEVDSKSQCIDILKQRNYYIIDIQEEIVKQDILDFSSFKKVKVKDIAVFCRQFATLINAGIP
IVTSLVTMREQVENKRLKNALREVYEEVQKGRTLSDAMKRHSDVFPMLLYNMVEVGEVSGTLDKVMNEMAEHYEKENELN
QKIKSALTYPVIVSIVAILVVIFLLTNVLPIFVGMFENAGVQLPLPTRILLAISGSISKYWYFYIGVILVISYSISSFLK
TPQGRCIYDRMLLNMPIFAPLNKKILISRFTRTLGTLISAGVPLMKAMEVVEKVVGNTVVAEGLKKAQDDIKKGLPLSEP
LKRIGIFPPMVIQMIGIGESSGSLDSILNKTADFYDGEVDTAVSQMTTLLEPLIIVMLATVVGFIVISIIMPLFELYNFI
GQ

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=402, Percent_Identity=30.3482587064677, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1786295, Length=398, Percent_Identity=26.3819095477387, Blast_Score=158, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45116; Mature: 44985

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLYAYRARDMGGNLVTGTLEVDSKSQCIDILKQRNYYIIDIQEEIVKQDILDFSSFKKV
CCCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCHH
KVKDIAVFCRQFATLINAGIPIVTSLVTMREQVENKRLKNALREVYEEVQKGRTLSDAMK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RHSDVFPMLLYNMVEVGEVSGTLDKVMNEMAEHYEKENELNQKIKSALTYPVIVSIVAIL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIFLLTNVLPIFVGMFENAGVQLPLPTRILLAISGSISKYWYFYIGVILVISYSISSFL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KTPQGRCIYDRMLLNMPIFAPLNKKILISRFTRTLGTLISAGVPLMKAMEVVEKVVGNTV
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
VAEGLKKAQDDIKKGLPLSEPLKRIGIFPPMVIQMIGIGESSGSLDSILNKTADFYDGEV
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHH
DTAVSQMTTLLEPLIIVMLATVVGFIVISIIMPLFELYNFIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLYAYRARDMGGNLVTGTLEVDSKSQCIDILKQRNYYIIDIQEEIVKQDILDFSSFKKV
CCCHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCHH
KVKDIAVFCRQFATLINAGIPIVTSLVTMREQVENKRLKNALREVYEEVQKGRTLSDAMK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RHSDVFPMLLYNMVEVGEVSGTLDKVMNEMAEHYEKENELNQKIKSALTYPVIVSIVAIL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVIFLLTNVLPIFVGMFENAGVQLPLPTRILLAISGSISKYWYFYIGVILVISYSISSFL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KTPQGRCIYDRMLLNMPIFAPLNKKILISRFTRTLGTLISAGVPLMKAMEVVEKVVGNTV
CCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
VAEGLKKAQDDIKKGLPLSEPLKRIGIFPPMVIQMIGIGESSGSLDSILNKTADFYDGEV
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHH
DTAVSQMTTLLEPLIIVMLATVVGFIVISIIMPLFELYNFIGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]