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The map label for this gene is aroE [H]

Identifier: 167040141

GI number: 167040141

Start: 1534659

End: 1535513

Strand: Direct

Name: aroE [H]

Synonym: Teth514_1503

Alternate gene names: 167040141

Gene position: 1534659-1535513 (Clockwise)

Preceding gene: 167040140

Following gene: 167040142

Centisome position: 62.45

GC content: 32.28

Gene sequence:

>855_bases
ATGGAGATTAATTCAAATACTAAACTGTATGGTCTTATAGGGCATCCTGTAGAACATAGTTTATCCCCTTTAATACATAA
CTATGCTTTTAAGTCTTTAAATTTAAATTGTGTCTACACTGTTTTTGATGTTTTGCCAGAAAAGCTTGAAGATGCAGTAA
ATGGAGTAAAAGCTTTGGGAATAAAAGGAGTTAATGTGACTGTGCCACATAAAGAGAAGATAATTAAATACTTAGATGTG
GTTTCAGAAGAAGCTTTAAAAATTGGCGCAGTCAATACTGTAGTCAATGAAGAAGGAATATTAAAAGGCTATAATACGGA
TGTCTATGGCTTTATAGACTCATTAACAGAAGTAGGAGAAAAAATTGAAGGAAGAAAAGCTGTTGTCTTAGGAGCTGGTG
GAGCTTCTAAAGCTGTTTGTGTCGCCCTTGCTCTAAAAGGGATAGATTCGATAATAATTGCCAATAGAAGTGTTGAGAGA
GCAAAAGATTTGTCAGAGTACATTAAAAAAGAATTTAAGATTCAGTGTGATTACTGCAGTATAAATGAAGTAAAAGAACT
ACCAGAAATAGATATACTTGTTAATACTACAAGCGTAGGAATGTATCCAAATACAGAAGATTCTCCTGCTGATGAAAAAG
TGGTTTTGAAAGCTAAATTTGTCTATGACCTTATTTACAATCCTTTTGAAACTGCTCTTTTAAAACATGCGAAAAAGAAT
GGAATAAAGTATTCTAATGGACTTTCTATGTTGGTAAATCAAGCTAATTATTCTTTCAAATTATGGACAGGGGGATTTTT
CGACAAAAATTTGGTATACAGGTATTTAAAAGAAGGAATTACGCATAATTTGTAG

Upstream 100 bases:

>100_bases
TTATATACTATTTTGGTAAAACCTCTATCAGAAGAGGAATTAGGATGGACTAAACTTATGAGAAAAGCGGAAAAACATGT
ACTTAAAAGGATTGAGAGAT

Downstream 100 bases:

>100_bases
AATATTTTATAAAGAGTAGATGAAGTGAGGCTATATGTGGGCACTTTATGCCTCACGGATACAGTGGTGCAACCGGCTTT
ATGTCGGCTTTATTATTTTT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MEINSNTKLYGLIGHPVEHSLSPLIHNYAFKSLNLNCVYTVFDVLPEKLEDAVNGVKALGIKGVNVTVPHKEKIIKYLDV
VSEEALKIGAVNTVVNEEGILKGYNTDVYGFIDSLTEVGEKIEGRKAVVLGAGGASKAVCVALALKGIDSIIIANRSVER
AKDLSEYIKKEFKIQCDYCSINEVKELPEIDILVNTTSVGMYPNTEDSPADEKVVLKAKFVYDLIYNPFETALLKHAKKN
GIKYSNGLSMLVNQANYSFKLWTGGFFDKNLVYRYLKEGITHNL

Sequences:

>Translated_284_residues
MEINSNTKLYGLIGHPVEHSLSPLIHNYAFKSLNLNCVYTVFDVLPEKLEDAVNGVKALGIKGVNVTVPHKEKIIKYLDV
VSEEALKIGAVNTVVNEEGILKGYNTDVYGFIDSLTEVGEKIEGRKAVVLGAGGASKAVCVALALKGIDSIIIANRSVER
AKDLSEYIKKEFKIQCDYCSINEVKELPEIDILVNTTSVGMYPNTEDSPADEKVVLKAKFVYDLIYNPFETALLKHAKKN
GIKYSNGLSMLVNQANYSFKLWTGGFFDKNLVYRYLKEGITHNL
>Mature_284_residues
MEINSNTKLYGLIGHPVEHSLSPLIHNYAFKSLNLNCVYTVFDVLPEKLEDAVNGVKALGIKGVNVTVPHKEKIIKYLDV
VSEEALKIGAVNTVVNEEGILKGYNTDVYGFIDSLTEVGEKIEGRKAVVLGAGGASKAVCVALALKGIDSIIIANRSVER
AKDLSEYIKKEFKIQCDYCSINEVKELPEIDILVNTTSVGMYPNTEDSPADEKVVLKAKFVYDLIYNPFETALLKHAKKN
GIKYSNGLSMLVNQANYSFKLWTGGFFDKNLVYRYLKEGITHNL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=286, Percent_Identity=33.9160839160839, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1789675, Length=276, Percent_Identity=34.0579710144928, Blast_Score=134, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=274, Percent_Identity=32.8467153284672, Blast_Score=102, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31444; Mature: 31444

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINSNTKLYGLIGHPVEHSLSPLIHNYAFKSLNLNCVYTVFDVLPEKLEDAVNGVKALG
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
IKGVNVTVPHKEKIIKYLDVVSEEALKIGAVNTVVNEEGILKGYNTDVYGFIDSLTEVGE
CCCCEEECCCHHHHHHHHHHHHHHHHHHCHHHHEECCCCCEECCCCHHHHHHHHHHHHHH
KIEGRKAVVLGAGGASKAVCVALALKGIDSIIIANRSVERAKDLSEYIKKEFKIQCDYCS
HCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCCC
INEVKELPEIDILVNTTSVGMYPNTEDSPADEKVVLKAKFVYDLIYNPFETALLKHAKKN
HHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHC
GIKYSNGLSMLVNQANYSFKLWTGGFFDKNLVYRYLKEGITHNL
CCEECCCHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEINSNTKLYGLIGHPVEHSLSPLIHNYAFKSLNLNCVYTVFDVLPEKLEDAVNGVKALG
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
IKGVNVTVPHKEKIIKYLDVVSEEALKIGAVNTVVNEEGILKGYNTDVYGFIDSLTEVGE
CCCCEEECCCHHHHHHHHHHHHHHHHHHCHHHHEECCCCCEECCCCHHHHHHHHHHHHHH
KIEGRKAVVLGAGGASKAVCVALALKGIDSIIIANRSVERAKDLSEYIKKEFKIQCDYCS
HCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCCC
INEVKELPEIDILVNTTSVGMYPNTEDSPADEKVVLKAKFVYDLIYNPFETALLKHAKKN
HHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHC
GIKYSNGLSMLVNQANYSFKLWTGGFFDKNLVYRYLKEGITHNL
CCEECCCHHHEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]