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The map label for this gene is ruvB

Identifier: 167040094

GI number: 167040094

Start: 1487652

End: 1488668

Strand: Direct

Name: ruvB

Synonym: Teth514_1454

Alternate gene names: 167040094

Gene position: 1487652-1488668 (Clockwise)

Preceding gene: 167040093

Following gene: 167040095

Centisome position: 60.54

GC content: 37.76

Gene sequence:

>1017_bases
ATGGAGGAAAGAATACTAACTCAAAATTTTACACAGGAAGATGCCTCCGAATACAGTTTGCGTCCTAGGTGGCTTTCTGA
GTATATAGGTCAGCAAAAGATAAAAGAGGAATTAAAAATTTACATAGAAGCCGCTAAGATGAGGAAAGAGCCCCTTGACC
ATGTCCTATTATATGGTCCTCCTGGCCTTGGGAAAACGACTTTAGCCACAGTAATTTCTAATGAAATGGGAGTAGGAATA
AAAATAACCTCAGGTCCTGCTATAGAAAAGTCGGGAGATTTGGCAGCAATTTTGACTAATTTACAGGAAAATGACATACT
TTTTATAGATGAGATTCACAGGCTTAATAGAAGTGTGGAAGAGATTCTATATCCTGCAATGGAAGACTTTGAATTGGATA
TAGTAATAGGAAAAGGTCCAAGTGCCAGGTCTATAAGGCTTAGCCTTCCACGTTTTACTTTAATTGGTGCTACCACAAGA
GCTGCGCTTATGACTTCTCCTTTGAGAGACAGATTCGGGGTTATAAACCGTTTGGATTACTATTCTGTGGAGGAATTAAA
AGAAATAATTAAAAGGTCAGCGAATATTTTAAACATTGGAATTGATGAAAAGGCCGCTTTGGAGATTGCTAAAAGGTCAC
GGGGGACTCCCAGAATTGCCAATAGACTTTTAAAACGGGTGAGAGATTTCGCACAAGTAAGAGGAAATGGATACATTGAT
TTTAAAACTTCCAAAGAAGCTTTAGACGTATTAGGTGTAGATGAGATAGGATTAGAATACATTGATAGAAAGATTTTGGT
TTCTATTATAGAAAAGTTTGGGGGTGGTCCTGTAGGAATCGATGCTATTGCTGCATCAATAGGAGAAGATGGGGATACAA
TAGAGGATGTTTATGAACCTTATCTTTTGCAAATAGGTTTTTTAAACAGGACTCCGCGAGGGAGAGTTGTTACAAAATTG
GCTTATGATTACCTTAAATATCCTTATATAGAACAGGGGAGGATAGAAGGTGTTTGA

Upstream 100 bases:

>100_bases
AAGAGTGAAGCTATTTATGCTTTGGCAGATATCACCTGTGATAGCGTAGAAGATGCTGTAAAGCAAGCTTTGAAAAAATT
AATGAAATAGGGTGAATTAA

Downstream 100 bases:

>100_bases
TAGTTTTGGCAAAATGTTGATATTTATGGGAGCTATATTAATTTTAATAGGGGTGCTTTTTTCTGTGGGTTCAAAAATTG
GCTTAGGACGTTTGCCGGGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEERILTQNFTQEDASEYSLRPRWLSEYIGQQKIKEELKIYIEAAKMRKEPLDHVLLYGPPGLGKTTLATVISNEMGVGI
KITSGPAIEKSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPRFTLIGATTR
AALMTSPLRDRFGVINRLDYYSVEELKEIIKRSANILNIGIDEKAALEIAKRSRGTPRIANRLLKRVRDFAQVRGNGYID
FKTSKEALDVLGVDEIGLEYIDRKILVSIIEKFGGGPVGIDAIAASIGEDGDTIEDVYEPYLLQIGFLNRTPRGRVVTKL
AYDYLKYPYIEQGRIEGV

Sequences:

>Translated_338_residues
MEERILTQNFTQEDASEYSLRPRWLSEYIGQQKIKEELKIYIEAAKMRKEPLDHVLLYGPPGLGKTTLATVISNEMGVGI
KITSGPAIEKSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPRFTLIGATTR
AALMTSPLRDRFGVINRLDYYSVEELKEIIKRSANILNIGIDEKAALEIAKRSRGTPRIANRLLKRVRDFAQVRGNGYID
FKTSKEALDVLGVDEIGLEYIDRKILVSIIEKFGGGPVGIDAIAASIGEDGDTIEDVYEPYLLQIGFLNRTPRGRVVTKL
AYDYLKYPYIEQGRIEGV
>Mature_338_residues
MEERILTQNFTQEDASEYSLRPRWLSEYIGQQKIKEELKIYIEAAKMRKEPLDHVLLYGPPGLGKTTLATVISNEMGVGI
KITSGPAIEKSGDLAAILTNLQENDILFIDEIHRLNRSVEEILYPAMEDFELDIVIGKGPSARSIRLSLPRFTLIGATTR
AALMTSPLRDRFGVINRLDYYSVEELKEIIKRSANILNIGIDEKAALEIAKRSRGTPRIANRLLKRVRDFAQVRGNGYID
FKTSKEALDVLGVDEIGLEYIDRKILVSIIEKFGGGPVGIDAIAASIGEDGDTIEDVYEPYLLQIGFLNRTPRGRVVTKL
AYDYLKYPYIEQGRIEGV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=324, Percent_Identity=57.0987654320988, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1787119, Length=118, Percent_Identity=37.2881355932203, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_THEP3 (B0K956)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665005.1
- ProteinModelPortal:   B0K956
- SMR:   B0K956
- GeneID:   5873342
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1014
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   TPSE340099:TETH39_1014-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37978; Mature: 37978

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERILTQNFTQEDASEYSLRPRWLSEYIGQQKIKEELKIYIEAAKMRKEPLDHVLLYGP
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
PGLGKTTLATVISNEMGVGIKITSGPAIEKSGDLAAILTNLQENDILFIDEIHRLNRSVE
CCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHH
EILYPAMEDFELDIVIGKGPSARSIRLSLPRFTLIGATTRAALMTSPLRDRFGVINRLDY
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCC
YSVEELKEIIKRSANILNIGIDEKAALEIAKRSRGTPRIANRLLKRVRDFAQVRGNGYID
CCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
FKTSKEALDVLGVDEIGLEYIDRKILVSIIEKFGGGPVGIDAIAASIGEDGDTIEDVYEP
ECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHH
YLLQIGFLNRTPRGRVVTKLAYDYLKYPYIEQGRIEGV
HHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEERILTQNFTQEDASEYSLRPRWLSEYIGQQKIKEELKIYIEAAKMRKEPLDHVLLYGP
CCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
PGLGKTTLATVISNEMGVGIKITSGPAIEKSGDLAAILTNLQENDILFIDEIHRLNRSVE
CCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHH
EILYPAMEDFELDIVIGKGPSARSIRLSLPRFTLIGATTRAALMTSPLRDRFGVINRLDY
HHHHHCCCCCEEEEEEECCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHCCC
YSVEELKEIIKRSANILNIGIDEKAALEIAKRSRGTPRIANRLLKRVRDFAQVRGNGYID
CCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEE
FKTSKEALDVLGVDEIGLEYIDRKILVSIIEKFGGGPVGIDAIAASIGEDGDTIEDVYEP
ECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHH
YLLQIGFLNRTPRGRVVTKLAYDYLKYPYIEQGRIEGV
HHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA