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The map label for this gene is ccdA [H]

Identifier: 167040074

GI number: 167040074

Start: 1468418

End: 1469074

Strand: Direct

Name: ccdA [H]

Synonym: Teth514_1434

Alternate gene names: 167040074

Gene position: 1468418-1469074 (Clockwise)

Preceding gene: 167040073

Following gene: 167040075

Centisome position: 59.76

GC content: 32.12

Gene sequence:

>657_bases
GTGCCAATTTACACTGCATTTTTAGCAGGAATTGTTTCTTTTTTATCACCCTGTGTTTTGCCTTTAATTCCCGCTTATGT
GTCATATATTTTTGGAAATAAAAAGAATAATTTAATAAATTTGCTTCTCTTTGTTTTGGGATTTAGCATAGTGTTTGTTT
TAATGGGGGCGACTGCAAGCCAACTAGGAAAGCTTTTTTTAGCCTATAAAGACATTTTTAGGAAAGTAAGTGGGATAATA
ATTGTGCTTTTTGGACTTCAAATGACTGGGATTTTTAGACCAATATTTTTAAACAAAGAAGTCAAATTAATAAATATGGA
AAAGGTACAGACCGGTTATATAGGGTCATTAGTATTGGGTATAACTTTTGCAGCAGGATGGACACCTTGTGTAGGTCCAA
TTCTCGCTTCGATATTGTTGTATGCTGGGTCTGTCAGTACTTTAAGTGTAGGCGTGATATTGCTTTTTGCATATTCTATG
GGGCTTGGCATACCTTTTATAATTACAGCCTTATTGATTGACAAGTTTAAAAGTATGTATAAAAGGATTAACAAAATATT
GCCTTATATAGAGGTAATAAGTGGGGTTATTCTCATAATATTTGGAGTTCTCTTATATTTTAACATGCTAATCAAGATAA
GTGGATATTTTTATTAA

Upstream 100 bases:

>100_bases
GAATAGCGGTGTTTTATTATATATGAACGCTATTGTATTGTAGTTATAATTGTAATATAATATTTGATAGTTATACCCTA
TAGGGGAGGGAGGTGTAGAT

Downstream 100 bases:

>100_bases
GAGGTGGTTAGTGTGAAAAATAAAAGTTTAATTTTTACTATAATTGCTGTGATAGTTATAGGGGCACTTATTTTTGTGTT
GAATAATTACACAAAAAGTG

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPIYTAFLAGIVSFLSPCVLPLIPAYVSYIFGNKKNNLINLLLFVLGFSIVFVLMGATASQLGKLFLAYKDIFRKVSGII
IVLFGLQMTGIFRPIFLNKEVKLINMEKVQTGYIGSLVLGITFAAGWTPCVGPILASILLYAGSVSTLSVGVILLFAYSM
GLGIPFIITALLIDKFKSMYKRINKILPYIEVISGVILIIFGVLLYFNMLIKISGYFY

Sequences:

>Translated_218_residues
MPIYTAFLAGIVSFLSPCVLPLIPAYVSYIFGNKKNNLINLLLFVLGFSIVFVLMGATASQLGKLFLAYKDIFRKVSGII
IVLFGLQMTGIFRPIFLNKEVKLINMEKVQTGYIGSLVLGITFAAGWTPCVGPILASILLYAGSVSTLSVGVILLFAYSM
GLGIPFIITALLIDKFKSMYKRINKILPYIEVISGVILIIFGVLLYFNMLIKISGYFY
>Mature_217_residues
PIYTAFLAGIVSFLSPCVLPLIPAYVSYIFGNKKNNLINLLLFVLGFSIVFVLMGATASQLGKLFLAYKDIFRKVSGIII
VLFGLQMTGIFRPIFLNKEVKLINMEKVQTGYIGSLVLGITFAAGWTPCVGPILASILLYAGSVSTLSVGVILLFAYSMG
LGIPFIITALLIDKFKSMYKRINKILPYIEVISGVILIIFGVLLYFNMLIKISGYFY

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 23996; Mature: 23865

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIYTAFLAGIVSFLSPCVLPLIPAYVSYIFGNKKNNLINLLLFVLGFSIVFVLMGATAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
QLGKLFLAYKDIFRKVSGIIIVLFGLQMTGIFRPIFLNKEVKLINMEKVQTGYIGSLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
ITFAAGWTPCVGPILASILLYAGSVSTLSVGVILLFAYSMGLGIPFIITALLIDKFKSMY
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KRINKILPYIEVISGVILIIFGVLLYFNMLIKISGYFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIYTAFLAGIVSFLSPCVLPLIPAYVSYIFGNKKNNLINLLLFVLGFSIVFVLMGATAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
QLGKLFLAYKDIFRKVSGIIIVLFGLQMTGIFRPIFLNKEVKLINMEKVQTGYIGSLVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHH
ITFAAGWTPCVGPILASILLYAGSVSTLSVGVILLFAYSMGLGIPFIITALLIDKFKSMY
HHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KRINKILPYIEVISGVILIIFGVLLYFNMLIKISGYFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]