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The map label for this gene is adhB [H]

Identifier: 167039313

GI number: 167039313

Start: 681654

End: 682865

Strand: Direct

Name: adhB [H]

Synonym: Teth514_0654

Alternate gene names: 167039313

Gene position: 681654-682865 (Clockwise)

Preceding gene: 167039309

Following gene: 167039314

Centisome position: 27.74

GC content: 40.02

Gene sequence:

>1212_bases
ATGTGGGAAACTAAAATAAATCCCACCAAGATTTTTGAACTTCGGTGCAAGAATACAACTTATTTTGGAATAGGTAGTAT
AAAGAAGATAGAAGACATTCTAGAAGTTCTAAAACATAAGGGTATCGATAATGTCATTTTTGTAACCGGAAAGAATTCAT
ACAAAGTTAGTGGAGCTTGGGATGTGATAGAACCGGCTCTAAATACACTCGGCTTTAAATATTCACTTTATGACAAGGTC
GGACCTAATCCTACTGTTGATATGGTCGATGAAGCGGCCAAATTCGGCCGGGAAACTGGGGCGAAGGCTGTTATTGGCAT
TGGTGGTGGAAGCCCTATAGATACTGCAAAAAGTGTGGCTGTACTGTTAGAATATACTGATAAAAATGCAAGAGAACTTT
ATGAACTGAAATTCACGCCCGAAAAAGCTGCTCCTATTATAGCTATAAATCTTACTCATGGTACTGGTACGGAAGTAGAC
CGATTTGCAGTAGCTACAATTCCAGAAAAAAATTATAAGCCTGCAATAGCTTATGAGTGCCTCTATCCTATGTATGCTAT
AGATGATCCTGCTCTCATGATAAAGCTTGATAAAAAACAGACAATAGCTGTTACTATAGATGCTTTAAATCACGTTACCG
AAGCTGCCACTACTCTTGTGACATCACCTTACAGTATTCTATTGGCGAAAGAGGCAGTGAGGTTGATAGTTCGTTACCTC
CCTGTTGCTGTAAATGACCCTGAAAACCTTGTGGCTAGATATTATTTGCTTTATGCTTCTGCTATAGCTGGTATTTCTTT
TGACAATGGTCTCTTGCACCTTACTCATGCACTGGAGCACCCACTAAGTGCAGTAAAACCTGAGATTGCCCACGGTCTTG
GGCTTGGTGCTATACTGCCTGCAGTGGTAAAGACTATTTATCCTGCTGTTGCAGAGGTGTTAGCTGACATATACAGCCCT
ATCGTGCCTGGACTAAAAGGACTGCCTGCTGAAGCAGAATATGTAGCTAAAAAAGTCGAAGAATGGCTCTTCAATGTAGG
ATGTACTCAAAAACTTTCAGACTTTGGATTTACAAAAGATGATGTTCCAACCCTAGTAAAGCTTGCTAAAACGACACCTT
CTCTCGATGGATTACTTTCTATTGCACCAGTGGAAGCCACTGAAACTGTTATTGCCAAGATTTATGAAGAATCTCTTAAC
CCAATCTCTTAA

Upstream 100 bases:

>100_bases
TTTTCTTGACTCTAAAAATAAATCAAAAGTTTAATATTGATTATTTTTTAACAAAATGCTATAATTAGATTGATATAAAT
TTTACAAGGAGGTAATTAAA

Downstream 100 bases:

>100_bases
CCCATAGCCAAAGGCTATTCTGATACAAAGTGCCAAAAGGTTCAACAATTTAAAAAAACCCCACTTTTAGCCAATACAAA
AAGTGGGGTTTTCATCTTTA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MWETKINPTKIFELRCKNTTYFGIGSIKKIEDILEVLKHKGIDNVIFVTGKNSYKVSGAWDVIEPALNTLGFKYSLYDKV
GPNPTVDMVDEAAKFGRETGAKAVIGIGGGSPIDTAKSVAVLLEYTDKNARELYELKFTPEKAAPIIAINLTHGTGTEVD
RFAVATIPEKNYKPAIAYECLYPMYAIDDPALMIKLDKKQTIAVTIDALNHVTEAATTLVTSPYSILLAKEAVRLIVRYL
PVAVNDPENLVARYYLLYASAIAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILPAVVKTIYPAVAEVLADIYSP
IVPGLKGLPAEAEYVAKKVEEWLFNVGCTQKLSDFGFTKDDVPTLVKLAKTTPSLDGLLSIAPVEATETVIAKIYEESLN
PIS

Sequences:

>Translated_403_residues
MWETKINPTKIFELRCKNTTYFGIGSIKKIEDILEVLKHKGIDNVIFVTGKNSYKVSGAWDVIEPALNTLGFKYSLYDKV
GPNPTVDMVDEAAKFGRETGAKAVIGIGGGSPIDTAKSVAVLLEYTDKNARELYELKFTPEKAAPIIAINLTHGTGTEVD
RFAVATIPEKNYKPAIAYECLYPMYAIDDPALMIKLDKKQTIAVTIDALNHVTEAATTLVTSPYSILLAKEAVRLIVRYL
PVAVNDPENLVARYYLLYASAIAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILPAVVKTIYPAVAEVLADIYSP
IVPGLKGLPAEAEYVAKKVEEWLFNVGCTQKLSDFGFTKDDVPTLVKLAKTTPSLDGLLSIAPVEATETVIAKIYEESLN
PIS
>Mature_403_residues
MWETKINPTKIFELRCKNTTYFGIGSIKKIEDILEVLKHKGIDNVIFVTGKNSYKVSGAWDVIEPALNTLGFKYSLYDKV
GPNPTVDMVDEAAKFGRETGAKAVIGIGGGSPIDTAKSVAVLLEYTDKNARELYELKFTPEKAAPIIAINLTHGTGTEVD
RFAVATIPEKNYKPAIAYECLYPMYAIDDPALMIKLDKKQTIAVTIDALNHVTEAATTLVTSPYSILLAKEAVRLIVRYL
PVAVNDPENLVARYYLLYASAIAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILPAVVKTIYPAVAEVLADIYSP
IVPGLKGLPAEAEYVAKKVEEWLFNVGCTQKLSDFGFTKDDVPTLVKLAKTTPSLDGLLSIAPVEATETVIAKIYEESLN
PIS

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=435, Percent_Identity=26.8965517241379, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI48994951, Length=373, Percent_Identity=30.0268096514745, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87082107, Length=343, Percent_Identity=30.6122448979592, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=28.90625, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1787493, Length=298, Percent_Identity=29.8657718120805, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789386, Length=371, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=433, Percent_Identity=26.5588914549654, Blast_Score=128, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=288, Percent_Identity=32.6388888888889, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24657991, Length=407, Percent_Identity=27.5184275184275, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43764; Mature: 43764

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWETKINPTKIFELRCKNTTYFGIGSIKKIEDILEVLKHKGIDNVIFVTGKNSYKVSGAW
CCCCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCH
DVIEPALNTLGFKYSLYDKVGPNPTVDMVDEAAKFGRETGAKAVIGIGGGSPIDTAKSVA
HHHHHHHHHCCCEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHE
VLLEYTDKNARELYELKFTPEKAAPIIAINLTHGTGTEVDRFAVATIPEKNYKPAIAYEC
EEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHEEEEECCCCCCCCCHHHHH
LYPMYAIDDPALMIKLDKKQTIAVTIDALNHVTEAATTLVTSPYSILLAKEAVRLIVRYL
HCCHHCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
PVAVNDPENLVARYYLLYASAIAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILP
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCHHHHHCCCHHHHHH
AVVKTIYPAVAEVLADIYSPIVPGLKGLPAEAEYVAKKVEEWLFNVGCTQKLSDFGFTKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
DVPTLVKLAKTTPSLDGLLSIAPVEATETVIAKIYEESLNPIS
CHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MWETKINPTKIFELRCKNTTYFGIGSIKKIEDILEVLKHKGIDNVIFVTGKNSYKVSGAW
CCCCCCCCEEEEEEEECCCEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCH
DVIEPALNTLGFKYSLYDKVGPNPTVDMVDEAAKFGRETGAKAVIGIGGGSPIDTAKSVA
HHHHHHHHHCCCEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHE
VLLEYTDKNARELYELKFTPEKAAPIIAINLTHGTGTEVDRFAVATIPEKNYKPAIAYEC
EEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCHHEEEEECCCCCCCCCHHHHH
LYPMYAIDDPALMIKLDKKQTIAVTIDALNHVTEAATTLVTSPYSILLAKEAVRLIVRYL
HCCHHCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
PVAVNDPENLVARYYLLYASAIAGISFDNGLLHLTHALEHPLSAVKPEIAHGLGLGAILP
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCHHHHHCCCHHHHHH
AVVKTIYPAVAEVLADIYSPIVPGLKGLPAEAEYVAKKVEEWLFNVGCTQKLSDFGFTKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
DVPTLVKLAKTTPSLDGLLSIAPVEATETVIAKIYEESLNPIS
CHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]