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The map label for this gene is hemA [H]

Identifier: 167038984

GI number: 167038984

Start: 332114

End: 333301

Strand: Direct

Name: hemA [H]

Synonym: Teth514_0317

Alternate gene names: 167038984

Gene position: 332114-333301 (Clockwise)

Preceding gene: 167038983

Following gene: 167038985

Centisome position: 13.52

GC content: 32.58

Gene sequence:

>1188_bases
GTGGACATAAATAATATTAAGATGGTGGGAGTAGATAAGGATACTCCTTTAGAATTGAGAGAAAAAGTTTCTTTTAAAGA
TATTGGAGAGGCATTAATAAAATTAAAAGAGTTGGGACTGGAGGAGGTTGTAATACTTTCCACCTGTCACAGAAGTGAAA
TTTATTTCTATTCACAAAAAATATCCACGGATGAAGTAAAAGATTTTTTCATAAATTACTTTGGCTTAAAAGAAGATTTC
ATAAAATATTTAAGGCAAATTTACGGACTTGATGCAGTGGAACACATTTTTAGAGTTGCCTGTGGACTTGAATCTATGGT
AGTAGGTGAAGACCAAATATTGTCACAGGTGAAGGAGGCTATAGATACCGCACAGACTTTCAACTCTTCCGGAAAGATAC
TTTTTAAACTCTTTAGGGATGCAGTAACTCTTGGGAAAAAAGCTCGTACAGATACGGGTATAAAAGATCTGGCTTTGTCT
ATAAGCTATATTGCAGTTAAATTTGTTCAAGAAGTATTTGAGGATATAAAAGGCAAAAAGGCTTTTGTGATAGGTCTTGG
CGAGATGGGGCAAAATGCTATGAAAAATCTTTTAGATAAAGGTGCTGATGTATTTGTTACAAACAGGACTTTTTCAAAAG
CTATTGAATTAAAGGAGCAAATTCCACAGATAAATATTGTACCTTATGAAGAGAAGTACCTGCACATTGTCACCAGTGAT
ATTGTAATAAGTGCTACAAATGCTCCTCACTACACAGTAAATTATGATAAGTTTAAAAAAATATACGACGGCAGAAAAAT
TTGTATGGTGGATATAGCTCTTCCCAGGGATATAGACCCGAGAATTGGACAAATAGAAGGAGTAAGTCTTTATACTATTG
ACGATCTAAAAAAGACAGCGGAGGAAAACAAAAAAGAGAGGCTTTTACTTATTCCCGTTATTGAAAAAATGGTGAAAGAG
GAAGTGAATAAATTTGAAAAATGGTACAAAACACTTGAAATAGAGCCTTATATAAAAGAAGTAAGTAGATATGCCAATGA
AGTTTGTAACACAGAATTTCAAAGAATTGTAAATAAATTGACTGACGTATCTGAAAAAGACAAGGAAAATATAAAAATCG
CTTTAAAAAGAGTTGCAAATAAAATGGCTAATAAAATGATAACATACCTTAAAGAAAATGCATATTAG

Upstream 100 bases:

>100_bases
AAAATGCTGGGTATTCCTGTGATTTTAATAAAAAGGCCTGATATAAATTATCCTATTGTAGTAACAGATGTTGATAGTCT
CATAAATGAGGTGACAAAAA

Downstream 100 bases:

>100_bases
AATCTGGAGGGAAAGATGAAAAAAGTTATAAAAGTCGGCACAAGGTCAAGTGAATTGGCTTTAAAGCAAACTGCAATGGT
TATAAATGAAATAAAAAAGT

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MDINNIKMVGVDKDTPLELREKVSFKDIGEALIKLKELGLEEVVILSTCHRSEIYFYSQKISTDEVKDFFINYFGLKEDF
IKYLRQIYGLDAVEHIFRVACGLESMVVGEDQILSQVKEAIDTAQTFNSSGKILFKLFRDAVTLGKKARTDTGIKDLALS
ISYIAVKFVQEVFEDIKGKKAFVIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIELKEQIPQINIVPYEEKYLHIVTSD
IVISATNAPHYTVNYDKFKKIYDGRKICMVDIALPRDIDPRIGQIEGVSLYTIDDLKKTAEENKKERLLLIPVIEKMVKE
EVNKFEKWYKTLEIEPYIKEVSRYANEVCNTEFQRIVNKLTDVSEKDKENIKIALKRVANKMANKMITYLKENAY

Sequences:

>Translated_395_residues
MDINNIKMVGVDKDTPLELREKVSFKDIGEALIKLKELGLEEVVILSTCHRSEIYFYSQKISTDEVKDFFINYFGLKEDF
IKYLRQIYGLDAVEHIFRVACGLESMVVGEDQILSQVKEAIDTAQTFNSSGKILFKLFRDAVTLGKKARTDTGIKDLALS
ISYIAVKFVQEVFEDIKGKKAFVIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIELKEQIPQINIVPYEEKYLHIVTSD
IVISATNAPHYTVNYDKFKKIYDGRKICMVDIALPRDIDPRIGQIEGVSLYTIDDLKKTAEENKKERLLLIPVIEKMVKE
EVNKFEKWYKTLEIEPYIKEVSRYANEVCNTEFQRIVNKLTDVSEKDKENIKIALKRVANKMANKMITYLKENAY
>Mature_395_residues
MDINNIKMVGVDKDTPLELREKVSFKDIGEALIKLKELGLEEVVILSTCHRSEIYFYSQKISTDEVKDFFINYFGLKEDF
IKYLRQIYGLDAVEHIFRVACGLESMVVGEDQILSQVKEAIDTAQTFNSSGKILFKLFRDAVTLGKKARTDTGIKDLALS
ISYIAVKFVQEVFEDIKGKKAFVIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIELKEQIPQINIVPYEEKYLHIVTSD
IVISATNAPHYTVNYDKFKKIYDGRKICMVDIALPRDIDPRIGQIEGVSLYTIDDLKKTAEENKKERLLLIPVIEKMVKE
EVNKFEKWYKTLEIEPYIKEVSRYANEVCNTEFQRIVNKLTDVSEKDKENIKIALKRVANKMANKMITYLKENAY

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=348, Percent_Identity=29.3103448275862, Blast_Score=146, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 45400; Mature: 45400

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINNIKMVGVDKDTPLELREKVSFKDIGEALIKLKELGLEEVVILSTCHRSEIYFYSQK
CCCCCEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECC
ISTDEVKDFFINYFGLKEDFIKYLRQIYGLDAVEHIFRVACGLESMVVGEDQILSQVKEA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHCCHHHHHHHHHHH
IDTAQTFNSSGKILFKLFRDAVTLGKKARTDTGIKDLALSISYIAVKFVQEVFEDIKGKK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
AFVIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIELKEQIPQINIVPYEEKYLHIVTSD
EEEEECHHCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCEEEECCCCCEEEEEEEC
IVISATNAPHYTVNYDKFKKIYDGRKICMVDIALPRDIDPRIGQIEGVSLYTIDDLKKTA
EEEEECCCCCEEECHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHH
EENKKERLLLIPVIEKMVKEEVNKFEKWYKTLEIEPYIKEVSRYANEVCNTEFQRIVNKL
HCCHHCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TDVSEKDKENIKIALKRVANKMANKMITYLKENAY
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDINNIKMVGVDKDTPLELREKVSFKDIGEALIKLKELGLEEVVILSTCHRSEIYFYSQK
CCCCCEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECC
ISTDEVKDFFINYFGLKEDFIKYLRQIYGLDAVEHIFRVACGLESMVVGEDQILSQVKEA
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHCCHHHHHHHHHHH
IDTAQTFNSSGKILFKLFRDAVTLGKKARTDTGIKDLALSISYIAVKFVQEVFEDIKGKK
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
AFVIGLGEMGQNAMKNLLDKGADVFVTNRTFSKAIELKEQIPQINIVPYEEKYLHIVTSD
EEEEECHHCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCEEEECCCCCEEEEEEEC
IVISATNAPHYTVNYDKFKKIYDGRKICMVDIALPRDIDPRIGQIEGVSLYTIDDLKKTA
EEEEECCCCCEEECHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHH
EENKKERLLLIPVIEKMVKEEVNKFEKWYKTLEIEPYIKEVSRYANEVCNTEFQRIVNKL
HCCHHCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TDVSEKDKENIKIALKRVANKMANKMITYLKENAY
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA