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The map label for this gene is cobU [H]

Identifier: 167038972

GI number: 167038972

Start: 323524

End: 324078

Strand: Direct

Name: cobU [H]

Synonym: Teth514_0305

Alternate gene names: 167038972

Gene position: 323524-324078 (Clockwise)

Preceding gene: 167038971

Following gene: 167038973

Centisome position: 13.17

GC content: 36.94

Gene sequence:

>555_bases
ATGAGCCTTGTTATGATCACAGGCGGTGCAAGGTCTGGCAAAAGTGAATTTGCTGAAAAATTGGCTTTAGAAAAAGGAGG
AAACAGTGTCCTTTATATAGCTACTTCTATTCCTTTTGACGAAGAAATGAAGGAAAGGGTCAAAAGGCATAAAGAGAGAA
GGCCACCTTTTTGGCAGACAAAAGAAGTCTACAAAAATTTATATGACGTAATATCAAAAAGCAGTGCCAAAGTCGCATTG
ATTGACTGCCTTACAGTTATGATTACAAACCTATTAATGGAAGTTGACTTAACATGGGAGAATGCAGGAATGGAGGAGAT
TGATAATATAGAAAATCAGATTGCCGATGAAGTGGATGAAATATTGTCCGCTAAGAAAGATTTTAAAGGGGATATAATTC
TTGTAACAAATGAAGTGGGAATGGGATTAGTGCCCGAATACAAACTGGGCAGGATATTTAGAGATATAGCAGGCAGGATG
AATAAAAAAGTGGCAGATGCTGCAGATGAAGTTTATTTAATGGTTTCAGGAATACCTCTTAAAATAAAGGGATGA

Upstream 100 bases:

>100_bases
TGCTATAAAAAGACATGAAGACAATGAAAAATTGATACAGGCTTTGAAAGAAATAGATATAAAAGACTTGGTAGAAGATA
AAGAAAGGGTTGTAATATAA

Downstream 100 bases:

>100_bases
TTGAAAGGGATGCAATATCTTTATGGAAGAAATTAAAAGATTGGTACTTGCGATGCAGTTTATGACACACCTTCCTATAC
CAATAGAAATTGATGTTGAA

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSLVMITGGARSGKSEFAEKLALEKGGNSVLYIATSIPFDEEMKERVKRHKERRPPFWQTKEVYKNLYDVISKSSAKVAL
IDCLTVMITNLLMEVDLTWENAGMEEIDNIENQIADEVDEILSAKKDFKGDIILVTNEVGMGLVPEYKLGRIFRDIAGRM
NKKVADAADEVYLMVSGIPLKIKG

Sequences:

>Translated_184_residues
MSLVMITGGARSGKSEFAEKLALEKGGNSVLYIATSIPFDEEMKERVKRHKERRPPFWQTKEVYKNLYDVISKSSAKVAL
IDCLTVMITNLLMEVDLTWENAGMEEIDNIENQIADEVDEILSAKKDFKGDIILVTNEVGMGLVPEYKLGRIFRDIAGRM
NKKVADAADEVYLMVSGIPLKIKG
>Mature_183_residues
SLVMITGGARSGKSEFAEKLALEKGGNSVLYIATSIPFDEEMKERVKRHKERRPPFWQTKEVYKNLYDVISKSSAKVALI
DCLTVMITNLLMEVDLTWENAGMEEIDNIENQIADEVDEILSAKKDFKGDIILVTNEVGMGLVPEYKLGRIFRDIAGRMN
KKVADAADEVYLMVSGIPLKIKG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=188, Percent_Identity=43.6170212765958, Blast_Score=153, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20632; Mature: 20501

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVMITGGARSGKSEFAEKLALEKGGNSVLYIATSIPFDEEMKERVKRHKERRPPFWQT
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCH
KEVYKNLYDVISKSSAKVALIDCLTVMITNLLMEVDLTWENAGMEEIDNIENQIADEVDE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ILSAKKDFKGDIILVTNEVGMGLVPEYKLGRIFRDIAGRMNKKVADAADEVYLMVSGIPL
HHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEE
KIKG
EECC
>Mature Secondary Structure 
SLVMITGGARSGKSEFAEKLALEKGGNSVLYIATSIPFDEEMKERVKRHKERRPPFWQT
EEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCH
KEVYKNLYDVISKSSAKVALIDCLTVMITNLLMEVDLTWENAGMEEIDNIENQIADEVDE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ILSAKKDFKGDIILVTNEVGMGLVPEYKLGRIFRDIAGRMNKKVADAADEVYLMVSGIPL
HHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEE
KIKG
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]