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The map label for this gene is yesM [H]

Identifier: 167038892

GI number: 167038892

Start: 231940

End: 233448

Strand: Direct

Name: yesM [H]

Synonym: Teth514_0223

Alternate gene names: 167038892

Gene position: 231940-233448 (Clockwise)

Preceding gene: 167038891

Following gene: 167038893

Centisome position: 9.44

GC content: 30.68

Gene sequence:

>1509_bases
ATGAAAAAAGATATGTGGAGATTTACGGGCATAAGGCGAAAATTGATAGTTTATTACCTCATAATCACTATTTTAATGGG
TATCACAAGTTTTTATTCGTATTATAATGCAAAATCAGTTATAAATCGTTTAAAATCAATTTTTGTGGATTATATATACC
TTAACAATTTAAATGCGGATGTAAACATGTTGGAAACAGAAGTGGAGAAGTATTTATCTACCAAATCTTCGGACGCCCTT
TTAAATTATTATACTCTCTATAACAAACTTCAAGAACAAGCCTCCGCTATTTTAAATGAAAAAAACTATGACCAGGATGG
TTTAATGTTAAAGGATATAGGGAATATGATTGAAAGCCTTTTGAATGAAACTGACGCAGCAATAAATGCTAAAAGAGGCA
GGATAAGCAGCGAGTACATTGCACATTTTACGAGGTCCAATAAAATAAGTGAATATATAAAACTTTACATTAATAATCTT
CTCAACAGTAAATTGCAAGAGGGCTCTTTAAAATATGCATCTATAACAAAAAACATGGAGTTTATAAGCTATTTGAATGT
GTTTTTGATAATAGGTTCTATTCTTTTTAACATATTTCTTGCAATATTTTTTACCTATCGAATTACAAAACCTCTTATAG
ACCTTTCCCATTTGGCAGTGAGAGTTTCAAAAGGAGATTTTGATGTAAGACCGCTTTCTATAAAGACAAACGATGAGATA
AATATACTTGCAGAAGCTTTTAATAAGATGGTAGTAAGCATAAAAAATTATATAGGGGAAATCAAAAATCAGGCAGAAGT
AGAGAAAAAATTAAAAGAACAAGAGATGCAAAATCTCAAAATGAGAAATATTTTAAAAGAGGCAGAACTTAAGGCTTTGC
AGTCTCAAATAAATCCACATTTTCTCTTTAATACCTTAAATGCAGCTGCACAATTAGCGATGATGGAAGGGGCAGATAAA
TCTTCGGAGTTTATAGAAAACGTTGCAAACCTATTTAGATATAATCTAAAAAAATTGGATACTACAGTTACTTTGCAAGA
CGAGATAAACAATGTAAAGACATATATGTACATTTTGAAAACGAGATTTGGCGACAGAGTAGATTTTAAAGTAGATGTAG
ACGAAGGGGTTTTAGATGTAGAAATGCCTTGTACAATAATTCAGCCTGTAGTTGAAAATGCTTTTATTCACGGATTAGAA
GATACAGAAAAAGGAGGTTTTATTAAACTTGCGGTAAAGAAGGATAATGATAAAGTTTTAATAGAGGTTATTGACAATGG
GATAGGAATGAGTGAAGAAAAAGTAAGGGCAATATTATCAGCAGACAATGAGGATTTATCTAAAAGGCATGTTACGGGTA
TTGGCATGCACAATATCATAAACAGACTAAGACTTTTTTATAACACTTCTGCTATAGAAGATGTAATTGAGATAGATAGC
AAAATAGGAGAAGGAACAAAAGTTACTTTAAAAATTCCTTTAATGAAGGGTGATAAAGAAAATGATTAA

Upstream 100 bases:

>100_bases
TAATGTTTCTACATTTGTTGATATAGGAGTAAATGTTATTACTAAGGACAATGTCAAAGAATATTTCAAAAGAATACAAT
CAATAGAATAAGGTGATGGC

Downstream 100 bases:

>100_bases
ATTGTTTATTGCGGATGATGAGCAAATAGTTATAGATTCAATTAAATTTATCATAGAAAAGAATAATGTAAAAGCTGATA
TAATTGGTTTTGCTAAATCT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKKDMWRFTGIRRKLIVYYLIITILMGITSFYSYYNAKSVINRLKSIFVDYIYLNNLNADVNMLETEVEKYLSTKSSDAL
LNYYTLYNKLQEQASAILNEKNYDQDGLMLKDIGNMIESLLNETDAAINAKRGRISSEYIAHFTRSNKISEYIKLYINNL
LNSKLQEGSLKYASITKNMEFISYLNVFLIIGSILFNIFLAIFFTYRITKPLIDLSHLAVRVSKGDFDVRPLSIKTNDEI
NILAEAFNKMVVSIKNYIGEIKNQAEVEKKLKEQEMQNLKMRNILKEAELKALQSQINPHFLFNTLNAAAQLAMMEGADK
SSEFIENVANLFRYNLKKLDTTVTLQDEINNVKTYMYILKTRFGDRVDFKVDVDEGVLDVEMPCTIIQPVVENAFIHGLE
DTEKGGFIKLAVKKDNDKVLIEVIDNGIGMSEEKVRAILSADNEDLSKRHVTGIGMHNIINRLRLFYNTSAIEDVIEIDS
KIGEGTKVTLKIPLMKGDKEND

Sequences:

>Translated_502_residues
MKKDMWRFTGIRRKLIVYYLIITILMGITSFYSYYNAKSVINRLKSIFVDYIYLNNLNADVNMLETEVEKYLSTKSSDAL
LNYYTLYNKLQEQASAILNEKNYDQDGLMLKDIGNMIESLLNETDAAINAKRGRISSEYIAHFTRSNKISEYIKLYINNL
LNSKLQEGSLKYASITKNMEFISYLNVFLIIGSILFNIFLAIFFTYRITKPLIDLSHLAVRVSKGDFDVRPLSIKTNDEI
NILAEAFNKMVVSIKNYIGEIKNQAEVEKKLKEQEMQNLKMRNILKEAELKALQSQINPHFLFNTLNAAAQLAMMEGADK
SSEFIENVANLFRYNLKKLDTTVTLQDEINNVKTYMYILKTRFGDRVDFKVDVDEGVLDVEMPCTIIQPVVENAFIHGLE
DTEKGGFIKLAVKKDNDKVLIEVIDNGIGMSEEKVRAILSADNEDLSKRHVTGIGMHNIINRLRLFYNTSAIEDVIEIDS
KIGEGTKVTLKIPLMKGDKEND
>Mature_502_residues
MKKDMWRFTGIRRKLIVYYLIITILMGITSFYSYYNAKSVINRLKSIFVDYIYLNNLNADVNMLETEVEKYLSTKSSDAL
LNYYTLYNKLQEQASAILNEKNYDQDGLMLKDIGNMIESLLNETDAAINAKRGRISSEYIAHFTRSNKISEYIKLYINNL
LNSKLQEGSLKYASITKNMEFISYLNVFLIIGSILFNIFLAIFFTYRITKPLIDLSHLAVRVSKGDFDVRPLSIKTNDEI
NILAEAFNKMVVSIKNYIGEIKNQAEVEKKLKEQEMQNLKMRNILKEAELKALQSQINPHFLFNTLNAAAQLAMMEGADK
SSEFIENVANLFRYNLKKLDTTVTLQDEINNVKTYMYILKTRFGDRVDFKVDVDEGVLDVEMPCTIIQPVVENAFIHGLE
DTEKGGFIKLAVKKDNDKVLIEVIDNGIGMSEEKVRAILSADNEDLSKRHVTGIGMHNIINRLRLFYNTSAIEDVIEIDS
KIGEGTKVTLKIPLMKGDKEND

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=237, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788446, Length=254, Percent_Identity=29.1338582677165, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57549; Mature: 57549

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKDMWRFTGIRRKLIVYYLIITILMGITSFYSYYNAKSVINRLKSIFVDYIYLNNLNAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
VNMLETEVEKYLSTKSSDALLNYYTLYNKLQEQASAILNEKNYDQDGLMLKDIGNMIESL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LNETDAAINAKRGRISSEYIAHFTRSNKISEYIKLYINNLLNSKLQEGSLKYASITKNME
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHH
FISYLNVFLIIGSILFNIFLAIFFTYRITKPLIDLSHLAVRVSKGDFDVRPLSIKTNDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEECCCCH
NILAEAFNKMVVSIKNYIGEIKNQAEVEKKLKEQEMQNLKMRNILKEAELKALQSQINPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FLFNTLNAAAQLAMMEGADKSSEFIENVANLFRYNLKKLDTTVTLQDEINNVKTYMYILK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
TRFGDRVDFKVDVDEGVLDVEMPCTIIQPVVENAFIHGLEDTEKGGFIKLAVKKDNDKVL
HHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEE
IEVIDNGIGMSEEKVRAILSADNEDLSKRHVTGIGMHNIINRLRLFYNTSAIEDVIEIDS
EEEECCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
KIGEGTKVTLKIPLMKGDKEND
HCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKKDMWRFTGIRRKLIVYYLIITILMGITSFYSYYNAKSVINRLKSIFVDYIYLNNLNAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
VNMLETEVEKYLSTKSSDALLNYYTLYNKLQEQASAILNEKNYDQDGLMLKDIGNMIESL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LNETDAAINAKRGRISSEYIAHFTRSNKISEYIKLYINNLLNSKLQEGSLKYASITKNME
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHH
FISYLNVFLIIGSILFNIFLAIFFTYRITKPLIDLSHLAVRVSKGDFDVRPLSIKTNDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEECCCCH
NILAEAFNKMVVSIKNYIGEIKNQAEVEKKLKEQEMQNLKMRNILKEAELKALQSQINPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
FLFNTLNAAAQLAMMEGADKSSEFIENVANLFRYNLKKLDTTVTLQDEINNVKTYMYILK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
TRFGDRVDFKVDVDEGVLDVEMPCTIIQPVVENAFIHGLEDTEKGGFIKLAVKKDNDKVL
HHCCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEE
IEVIDNGIGMSEEKVRAILSADNEDLSKRHVTGIGMHNIINRLRLFYNTSAIEDVIEIDS
EEEECCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
KIGEGTKVTLKIPLMKGDKEND
HCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]