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The map label for this gene is macB [H]

Identifier: 167038869

GI number: 167038869

Start: 202596

End: 203771

Strand: Direct

Name: macB [H]

Synonym: Teth514_0200

Alternate gene names: 167038869

Gene position: 202596-203771 (Clockwise)

Preceding gene: 167038868

Following gene: 167038870

Centisome position: 8.24

GC content: 36.48

Gene sequence:

>1176_bases
GTGAGATATGTAGAAGCTTTGAAAATAGCTATACGCAGTATTTTAAGCAATAAAATGAGGTCTTTTCTCACCATGTTGGG
GATTATAATAGGTGTCACAGCTGTTATAGCCTTAGTAAGTATAGGCCAAGGCTCTACAAGAAGTGTTACTTCTCAGATAC
AGAGTATGGGTTCAAACCTCATAATGGTAAACGTAATGGGGAGAGGGGGAGAAAGCTCTTTAACTTATGACCAAGCCATT
GCTTTAAAAGACTCAAGCTTTATAGCTGCTATATCTCCGGTCATATCTACCAGTGTAACGGCTATGTACGGAAATAATTC
AGTGGACAACACAACAGTAAATGGAGTTAATGGAGATTATCAATCAATACGCGATCTACAAGTAGCAGCTGGCAGATTCA
TTTTGCCGATGGATGATGAAGGAAGGAACAAGGTGGCAGTTCTTGGCAGCAATGTAGCGAGAGAGCTTTTTGGCTTTACT
GACCCTATTGGCAAAACTATAAAATTAAATGGCCAAAACTTCACGGTAGTAGGTATTTTGTCCCAAAAAGGTTCTTCAAT
TGCAGGTTCTGATGATGATTCAATATTTATACCCCTTAAAACAATGTTCTACTTTGCGAAAAATAGAGATATAAGACAAA
TATATATAGAAGCAACAAGTCCAGATACCGTTGAACTCGCTAAAAACGAAATAAACAGCAAACTGCTAACTATATTTAAA
GGCGATGCAAATGCCTTTAGAATAATTGATCAATCACAAATTTTATCTACAGTAAATAGTGTTACTGCTACATTGAGCTT
GCTCCTTGGAGGAATTGCAGGAATATCCCTTTTAGTCGGTGGAATAGGCATAATGAACATAATGCTTGTATCTGTTACTG
AAAGGACGAGAGAGATAGGGATAAGAAAAGCATTAGGAGCCAAAAAGAAAGATATATTACTTCAGTTTATAATTGAATCA
TTAACTTTAAGCGGATTAGGAGGAATAGTGGGAATTATAGTAGGATACGTATTGTCGATGGTACTAGGCTCAGCTATGAA
TATAAATGCTAAGCCTTCTCTCTCTACAGTATTAATATCCTTTTCCTTCTCAGTAATTGTAGGATTGTTCTTTGGCGTAT
ATCCTGCAAATAAAGCTGCCAATTTAAATCCAATTGAAGCTCTAAGATATGAATAA

Upstream 100 bases:

>100_bases
CAGTAGTACTCATAACGCATGATCCTAATATAGCTGCACAAGCCAAAAGAATAGTAAGAATAAAAGATGGGCGCATTTTA
GAAAACGAGGTGGTAACACC

Downstream 100 bases:

>100_bases
AATACAAAGAAAGAGGGCATAAATTTATCAATTATAATGCTTGTCAATAAAACGTTGGTGGATTGGCTTATAAATCACAA
AGCAAAGTAGATAAAAATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRYVEALKIAIRSILSNKMRSFLTMLGIIIGVTAVIALVSIGQGSTRSVTSQIQSMGSNLIMVNVMGRGGESSLTYDQAI
ALKDSSFIAAISPVISTSVTAMYGNNSVDNTTVNGVNGDYQSIRDLQVAAGRFILPMDDEGRNKVAVLGSNVARELFGFT
DPIGKTIKLNGQNFTVVGILSQKGSSIAGSDDDSIFIPLKTMFYFAKNRDIRQIYIEATSPDTVELAKNEINSKLLTIFK
GDANAFRIIDQSQILSTVNSVTATLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAKKKDILLQFIIES
LTLSGLGGIVGIIVGYVLSMVLGSAMNINAKPSLSTVLISFSFSVIVGLFFGVYPANKAANLNPIEALRYE

Sequences:

>Translated_391_residues
MRYVEALKIAIRSILSNKMRSFLTMLGIIIGVTAVIALVSIGQGSTRSVTSQIQSMGSNLIMVNVMGRGGESSLTYDQAI
ALKDSSFIAAISPVISTSVTAMYGNNSVDNTTVNGVNGDYQSIRDLQVAAGRFILPMDDEGRNKVAVLGSNVARELFGFT
DPIGKTIKLNGQNFTVVGILSQKGSSIAGSDDDSIFIPLKTMFYFAKNRDIRQIYIEATSPDTVELAKNEINSKLLTIFK
GDANAFRIIDQSQILSTVNSVTATLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAKKKDILLQFIIES
LTLSGLGGIVGIIVGYVLSMVLGSAMNINAKPSLSTVLISFSFSVIVGLFFGVYPANKAANLNPIEALRYE
>Mature_391_residues
MRYVEALKIAIRSILSNKMRSFLTMLGIIIGVTAVIALVSIGQGSTRSVTSQIQSMGSNLIMVNVMGRGGESSLTYDQAI
ALKDSSFIAAISPVISTSVTAMYGNNSVDNTTVNGVNGDYQSIRDLQVAAGRFILPMDDEGRNKVAVLGSNVARELFGFT
DPIGKTIKLNGQNFTVVGILSQKGSSIAGSDDDSIFIPLKTMFYFAKNRDIRQIYIEATSPDTVELAKNEINSKLLTIFK
GDANAFRIIDQSQILSTVNSVTATLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAKKKDILLQFIIES
LTLSGLGGIVGIIVGYVLSMVLGSAMNINAKPSLSTVLISFSFSVIVGLFFGVYPANKAANLNPIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=404, Percent_Identity=35.6435643564356, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41655; Mature: 41655

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVEALKIAIRSILSNKMRSFLTMLGIIIGVTAVIALVSIGQGSTRSVTSQIQSMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
IMVNVMGRGGESSLTYDQAIALKDSSFIAAISPVISTSVTAMYGNNSVDNTTVNGVNGDY
EEEEEECCCCCCCCCHHHEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCEECCCCCCH
QSIRDLQVAAGRFILPMDDEGRNKVAVLGSNVARELFGFTDPIGKTIKLNGQNFTVVGIL
HHHHHHHHHCCEEEEECCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEECCCEEEEEEEE
SQKGSSIAGSDDDSIFIPLKTMFYFAKNRDIRQIYIEATSPDTVELAKNEINSKLLTIFK
ECCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCEEEEEEE
GDANAFRIIDQSQILSTVNSVTATLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIG
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKALGAKKKDILLQFIIESLTLSGLGGIVGIIVGYVLSMVLGSAMNINAKPSLSTVLIS
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FSFSVIVGLFFGVYPANKAANLNPIEALRYE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MRYVEALKIAIRSILSNKMRSFLTMLGIIIGVTAVIALVSIGQGSTRSVTSQIQSMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCE
IMVNVMGRGGESSLTYDQAIALKDSSFIAAISPVISTSVTAMYGNNSVDNTTVNGVNGDY
EEEEEECCCCCCCCCHHHEEEEECCCHHHHHHHHHHHCEEEEECCCCCCCCEECCCCCCH
QSIRDLQVAAGRFILPMDDEGRNKVAVLGSNVARELFGFTDPIGKTIKLNGQNFTVVGIL
HHHHHHHHHCCEEEEECCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEECCCEEEEEEEE
SQKGSSIAGSDDDSIFIPLKTMFYFAKNRDIRQIYIEATSPDTVELAKNEINSKLLTIFK
ECCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCCEEEEEEE
GDANAFRIIDQSQILSTVNSVTATLSLLLGGIAGISLLVGGIGIMNIMLVSVTERTREIG
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRKALGAKKKDILLQFIIESLTLSGLGGIVGIIVGYVLSMVLGSAMNINAKPSLSTVLIS
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
FSFSVIVGLFFGVYPANKAANLNPIEALRYE
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA