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The map label for this gene is ald [H]

Identifier: 167038777

GI number: 167038777

Start: 100427

End: 101551

Strand: Direct

Name: ald [H]

Synonym: Teth514_0104

Alternate gene names: 167038777

Gene position: 100427-101551 (Clockwise)

Preceding gene: 167038776

Following gene: 167038778

Centisome position: 4.09

GC content: 38.04

Gene sequence:

>1125_bases
ATGAAAATTGGCGTTCCAAAAGAGATAAAAACTGCAGAGGCTCGTGTGGCTATTACTCCTGCGGGAGTTGAAGCTTTTAT
AAAAAATGGCCATGAAGTATATATTGAAAAAAGTGCAGGAATGGGAAGTGGCATAACTGATGAAGAATATGCAAAGGTTG
GAGCGAAAATACTTAATACTGCAAAAGAAGTATTTGATGTAGCAGATATGATTATGAAGGTAAAAGAACCACAGCCAAGC
GAATATGACTATTTCAAAGAAGGACAGATTCTTTTTACTTATCTTCATTTAGCTCCTGATAAACAACAAACAGAAGCTCT
ATTAAGGAAAAAAGTAGTAGGGATTGCTTATGAGACAGTACAATTAGATAATGGAGCACTTCCTCTCTTAACTCCCATGA
GTGAAGTAGCTGGAAGGATGTCGGTGACAATAGGAGCTTATCTTCTTACCAACATAAATGAAGGAAGAGGAATTGTAATG
GGCGGAGTCCCAGGAGTAGAGCCAGCAGAAGTAGTAATAATAGGTGGGGGAACGGTAGGTACAAATGCAGCAAAGGTAGC
TATGGGGATGGGAGCAAGAGTTACAATATTGGATGTAAATCCAGCGAGACTTGCTTACCTTGATGACATATTTGGTGGAC
GAGTTACAACTTTGATGTCAAATAGTTTTAATATTGCTCAGAGTGTGAAGAAAGCAGATTTGCTAATAGGAGCAGTTTTG
ATACCTGGAGCAAAGGCGCCAAAACTTGTGACAGAAGAAATGGTAAAGACGATGAAGAAAGGTGCAGTAATAGTGGATGT
TGCAATAGACCAAGGTGGTTGTATAGAGACCTGTGATAGAACGACTTCTCACAAAGACCCGTACTTTATAAAACATGGAG
TAGTACATTATTCTGTGCCTAACATTCCAGGAGCGGTTCCGAGAACCTCTACTTTTGCTTTAACTAACGTAACATTGCAT
TATGCTTTAGAAATAGCAAATAAAGGATATAAGAAGGCTTTACTTGAAAATAAAGCTTTATTAAAAGGATTAAATGTTTA
TAAAGGAATGGTAACCTACAAACCTGTTGCAGATGCTCAAGGTTTAGAGTATGTTGACCCTGTTGAGGCTTTAAACAAAG
AATAA

Upstream 100 bases:

>100_bases
TTTTATAATTTCTATTTTTTGTTGAAGGATTTTTAATAGCTTTGTAGAATTAATATATTGAAAAGGTTTTGATAAAAGAT
TGATAAAGGAGAGATAGGAT

Downstream 100 bases:

>100_bases
GAATTTTCTGAAGGGAAATATCTACCTCTCACAAAGAAATTTTGTGGGAGGTTTTTTGTTGTTTACTAAAAAATCTCATG
TTATAATTTTTGTAAAATTA

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKIGVPKEIKTAEARVAITPAGVEAFIKNGHEVYIEKSAGMGSGITDEEYAKVGAKILNTAKEVFDVADMIMKVKEPQPS
EYDYFKEGQILFTYLHLAPDKQQTEALLRKKVVGIAYETVQLDNGALPLLTPMSEVAGRMSVTIGAYLLTNINEGRGIVM
GGVPGVEPAEVVIIGGGTVGTNAAKVAMGMGARVTILDVNPARLAYLDDIFGGRVTTLMSNSFNIAQSVKKADLLIGAVL
IPGAKAPKLVTEEMVKTMKKGAVIVDVAIDQGGCIETCDRTTSHKDPYFIKHGVVHYSVPNIPGAVPRTSTFALTNVTLH
YALEIANKGYKKALLENKALLKGLNVYKGMVTYKPVADAQGLEYVDPVEALNKE

Sequences:

>Translated_374_residues
MKIGVPKEIKTAEARVAITPAGVEAFIKNGHEVYIEKSAGMGSGITDEEYAKVGAKILNTAKEVFDVADMIMKVKEPQPS
EYDYFKEGQILFTYLHLAPDKQQTEALLRKKVVGIAYETVQLDNGALPLLTPMSEVAGRMSVTIGAYLLTNINEGRGIVM
GGVPGVEPAEVVIIGGGTVGTNAAKVAMGMGARVTILDVNPARLAYLDDIFGGRVTTLMSNSFNIAQSVKKADLLIGAVL
IPGAKAPKLVTEEMVKTMKKGAVIVDVAIDQGGCIETCDRTTSHKDPYFIKHGVVHYSVPNIPGAVPRTSTFALTNVTLH
YALEIANKGYKKALLENKALLKGLNVYKGMVTYKPVADAQGLEYVDPVEALNKE
>Mature_374_residues
MKIGVPKEIKTAEARVAITPAGVEAFIKNGHEVYIEKSAGMGSGITDEEYAKVGAKILNTAKEVFDVADMIMKVKEPQPS
EYDYFKEGQILFTYLHLAPDKQQTEALLRKKVVGIAYETVQLDNGALPLLTPMSEVAGRMSVTIGAYLLTNINEGRGIVM
GGVPGVEPAEVVIIGGGTVGTNAAKVAMGMGARVTILDVNPARLAYLDDIFGGRVTTLMSNSFNIAQSVKKADLLIGAVL
IPGAKAPKLVTEEMVKTMKKGAVIVDVAIDQGGCIETCDRTTSHKDPYFIKHGVVHYSVPNIPGAVPRTSTFALTNVTLH
YALEIANKGYKKALLENKALLKGLNVYKGMVTYKPVADAQGLEYVDPVEALNKE

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=347, Percent_Identity=31.700288184438, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI122939153, Length=347, Percent_Identity=31.700288184438, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1787887, Length=335, Percent_Identity=30.7462686567164, Blast_Score=128, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17550456, Length=347, Percent_Identity=31.9884726224784, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 40053; Mature: 40053

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVPKEIKTAEARVAITPAGVEAFIKNGHEVYIEKSAGMGSGITDEEYAKVGAKILNT
CCCCCCCCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
AKEVFDVADMIMKVKEPQPSEYDYFKEGQILFTYLHLAPDKQQTEALLRKKVVGIAYETV
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHEEEEEE
QLDNGALPLLTPMSEVAGRMSVTIGAYLLTNINEGRGIVMGGVPGVEPAEVVIIGGGTVG
EECCCCCCEECCHHHHCCCEEEEEEEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCC
TNAAKVAMGMGARVTILDVNPARLAYLDDIFGGRVTTLMSNSFNIAQSVKKADLLIGAVL
CCHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHEEEEEE
IPGAKAPKLVTEEMVKTMKKGAVIVDVAIDQGGCIETCDRTTSHKDPYFIKHGVVHYSVP
ECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHCCCCCCCCCEEEECCEEEEECC
NIPGAVPRTSTFALTNVTLHYALEIANKGYKKALLENKALLKGLNVYKGMVTYKPVADAQ
CCCCCCCCCCEEEEEEEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCC
GLEYVDPVEALNKE
CCCCCCHHHHHCCC
>Mature Secondary Structure
MKIGVPKEIKTAEARVAITPAGVEAFIKNGHEVYIEKSAGMGSGITDEEYAKVGAKILNT
CCCCCCCCCCCCCEEEEEECCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
AKEVFDVADMIMKVKEPQPSEYDYFKEGQILFTYLHLAPDKQQTEALLRKKVVGIAYETV
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHEEEEEE
QLDNGALPLLTPMSEVAGRMSVTIGAYLLTNINEGRGIVMGGVPGVEPAEVVIIGGGTVG
EECCCCCCEECCHHHHCCCEEEEEEEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCC
TNAAKVAMGMGARVTILDVNPARLAYLDDIFGGRVTTLMSNSFNIAQSVKKADLLIGAVL
CCHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHHEEEEEE
IPGAKAPKLVTEEMVKTMKKGAVIVDVAIDQGGCIETCDRTTSHKDPYFIKHGVVHYSVP
ECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHCCCCCCCCCEEEECCEEEEECC
NIPGAVPRTSTFALTNVTLHYALEIANKGYKKALLENKALLKGLNVYKGMVTYKPVADAQ
CCCCCCCCCCEEEEEEEEEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCC
GLEYVDPVEALNKE
CCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA