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The map label for this gene is murA1 [H]

Identifier: 167038776

GI number: 167038776

Start: 99009

End: 100259

Strand: Direct

Name: murA1 [H]

Synonym: Teth514_0103

Alternate gene names: 167038776

Gene position: 99009-100259 (Clockwise)

Preceding gene: 167038775

Following gene: 167038777

Centisome position: 4.03

GC content: 37.41

Gene sequence:

>1251_bases
GTGATAACAACGAAATTTATTGTTGAAAAAAGCCCACCTCTTAAAGGAAGTGTAAAAATAAGTGGTGCTAAAAATTCTGT
ATTACCTATAATTGCCGCTTCTTTGTTGTCATCAGGAGAAATAGTGTTAGATGACATACCTACTTTAGAGGATGTCAATG
TCATGATAGAGTTAATTAAGCATTTTGGTGCTATATGTGAATTTGAAAATGAGAAATTAAAGATAAAAGTGGATATTAAA
GATGTAGAAGCCCCATATGATTTGGTGAAGAAAATGAGAGCATCGTTTTTGGTGATGGGACCCATACTTGCAAGGTTGGG
GCACGCTAAAATTTCTATGCCAGGTGGGTGCGCTATTGGTTCTCGACCAATAGATTTGCATTTAAAAGGATTTCAAACTT
TGGGAGCAGATATCACCATAGGACATGGTTATGTAGAAGCACGAGCCAAAAAATTGACAGGCAAAAAAATTTATTTAGAT
TTTCCAAGTGTTGGGGCTACAGAAAACATCATGATGGCGGCAGTTTTTGCGGAAGGAGTTACTATAATAGAAAACGCTGC
GGAAGAGCCGGAAATTGTTGACCTTGCCAATTTTCTCAACAAGATGGGAGCAAATATTAAAGGCGCGGGGACAGATACAA
TAAGAATTGAAGGAGTAAAGGAGCTAAAAGGGGCTGAGCATACTGTCATACCAGATAGAATTGAAGCAGGGACTTTTATG
GTAGCAGCTGCAATGACTGGAGGAAATGTTCTTATAGAAAATGTCATAGTGGATCATGTAAGGTCTATAATTGCGAAATT
AACAGAATGCGGAATTAAGATAACAGAAGAACCTAAGGGACTGCGAGTCAAAGGAATCAAAAATTATAAAGCAGTGGACA
TAAAAACTCTTCCTTATCCAGGCTTTCCTACAGATATGCAAGCTCAAATGATGGTTATGATGACAGTGGCAAAAGGGACA
AGCGTTATAATAGAAACAGTTTTTGAAAATAGATTTATGCATGTGGATGAGCTAAAGCGTATGGGGGCAAATATAAAGAT
AGAAGGGAGAAGCGCTGTTGTTACAGGAGTAGATCATTTGACAGGTGCAGAAGTTAAAGCAACGGATTTAAGGGCGGGAG
CAGCCTTAGTATTGGCAGGACTTATTGCAGAAGGTAGGACTGAAATAAACGATATTTATCATATTGACAGAGGTTATGTA
AAAATGGAAGAAAAGTTAAAAAATCTTGGTGCAATCATATATAGAATATAA

Upstream 100 bases:

>100_bases
AAAAATAAATTTAAACGTAGCAATAAGATATAGTTCTTTTGACGATAAAACTTATATATGGGTGGCGACACCTATTATAG
CTATAGAATATTAAAAGAGG

Downstream 100 bases:

>100_bases
AGGCGTCATGTTGCGCCTTTTTAAATTTACGAAAAATTTTAAGAAAGTATGTTGTTTACTTAAAAGTTTTTATAATTTCT
ATTTTTTGTTGAAGGATTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MITTKFIVEKSPPLKGSVKISGAKNSVLPIIAASLLSSGEIVLDDIPTLEDVNVMIELIKHFGAICEFENEKLKIKVDIK
DVEAPYDLVKKMRASFLVMGPILARLGHAKISMPGGCAIGSRPIDLHLKGFQTLGADITIGHGYVEARAKKLTGKKIYLD
FPSVGATENIMMAAVFAEGVTIIENAAEEPEIVDLANFLNKMGANIKGAGTDTIRIEGVKELKGAEHTVIPDRIEAGTFM
VAAAMTGGNVLIENVIVDHVRSIIAKLTECGIKITEEPKGLRVKGIKNYKAVDIKTLPYPGFPTDMQAQMMVMMTVAKGT
SVIIETVFENRFMHVDELKRMGANIKIEGRSAVVTGVDHLTGAEVKATDLRAGAALVLAGLIAEGRTEINDIYHIDRGYV
KMEEKLKNLGAIIYRI

Sequences:

>Translated_416_residues
MITTKFIVEKSPPLKGSVKISGAKNSVLPIIAASLLSSGEIVLDDIPTLEDVNVMIELIKHFGAICEFENEKLKIKVDIK
DVEAPYDLVKKMRASFLVMGPILARLGHAKISMPGGCAIGSRPIDLHLKGFQTLGADITIGHGYVEARAKKLTGKKIYLD
FPSVGATENIMMAAVFAEGVTIIENAAEEPEIVDLANFLNKMGANIKGAGTDTIRIEGVKELKGAEHTVIPDRIEAGTFM
VAAAMTGGNVLIENVIVDHVRSIIAKLTECGIKITEEPKGLRVKGIKNYKAVDIKTLPYPGFPTDMQAQMMVMMTVAKGT
SVIIETVFENRFMHVDELKRMGANIKIEGRSAVVTGVDHLTGAEVKATDLRAGAALVLAGLIAEGRTEINDIYHIDRGYV
KMEEKLKNLGAIIYRI
>Mature_416_residues
MITTKFIVEKSPPLKGSVKISGAKNSVLPIIAASLLSSGEIVLDDIPTLEDVNVMIELIKHFGAICEFENEKLKIKVDIK
DVEAPYDLVKKMRASFLVMGPILARLGHAKISMPGGCAIGSRPIDLHLKGFQTLGADITIGHGYVEARAKKLTGKKIYLD
FPSVGATENIMMAAVFAEGVTIIENAAEEPEIVDLANFLNKMGANIKGAGTDTIRIEGVKELKGAEHTVIPDRIEAGTFM
VAAAMTGGNVLIENVIVDHVRSIIAKLTECGIKITEEPKGLRVKGIKNYKAVDIKTLPYPGFPTDMQAQMMVMMTVAKGT
SVIIETVFENRFMHVDELKRMGANIKIEGRSAVVTGVDHLTGAEVKATDLRAGAALVLAGLIAEGRTEINDIYHIDRGYV
KMEEKLKNLGAIIYRI

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=51.4354066985646, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45005; Mature: 45005

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTKFIVEKSPPLKGSVKISGAKNSVLPIIAASLLSSGEIVLDDIPTLEDVNVMIELIK
CCCEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
HFGAICEFENEKLKIKVDIKDVEAPYDLVKKMRASFLVMGPILARLGHAKISMPGGCAIG
HHCCCEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
SRPIDLHLKGFQTLGADITIGHGYVEARAKKLTGKKIYLDFPSVGATENIMMAAVFAEGV
CCCEEEEEECHHHCCCEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCHHHEEHHHHCCH
TIIENAAEEPEIVDLANFLNKMGANIKGAGTDTIRIEGVKELKGAEHTVIPDRIEAGTFM
HEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCEEE
VAAAMTGGNVLIENVIVDHVRSIIAKLTECGIKITEEPKGLRVKGIKNYKAVDIKTLPYP
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCEEEEEEEECCCC
GFPTDMQAQMMVMMTVAKGTSVIIETVFENRFMHVDELKRMGANIKIEGRSAVVTGVDHL
CCCCCHHHHEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCCEEEEECCHHC
TGAEVKATDLRAGAALVLAGLIAEGRTEINDIYHIDRGYVKMEEKLKNLGAIIYRI
CCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHEEECCCHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MITTKFIVEKSPPLKGSVKISGAKNSVLPIIAASLLSSGEIVLDDIPTLEDVNVMIELIK
CCCEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
HFGAICEFENEKLKIKVDIKDVEAPYDLVKKMRASFLVMGPILARLGHAKISMPGGCAIG
HHCCCEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
SRPIDLHLKGFQTLGADITIGHGYVEARAKKLTGKKIYLDFPSVGATENIMMAAVFAEGV
CCCEEEEEECHHHCCCEEEECCCHHHHHHHHCCCCEEEEECCCCCCCCHHHEEHHHHCCH
TIIENAAEEPEIVDLANFLNKMGANIKGAGTDTIRIEGVKELKGAEHTVIPDRIEAGTFM
HEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCEEE
VAAAMTGGNVLIENVIVDHVRSIIAKLTECGIKITEEPKGLRVKGIKNYKAVDIKTLPYP
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCEEEEEEEECCCC
GFPTDMQAQMMVMMTVAKGTSVIIETVFENRFMHVDELKRMGANIKIEGRSAVVTGVDHL
CCCCCHHHHEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCCEEEEECCHHC
TGAEVKATDLRAGAALVLAGLIAEGRTEINDIYHIDRGYVKMEEKLKNLGAIIYRI
CCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHEEECCCHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]