Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 16520029

GI number: 16520029

Start: 93164

End: 94378

Strand: Direct

Name: Not Available

Synonym: NGR_a00760

Alternate gene names: 16520029

Gene position: 93164-94378 (Clockwise)

Preceding gene: 16520030

Following gene: 16520028

Centisome position: 17.38

GC content: 64.03

Gene sequence:

>1215_bases
ATGACCAGGACAGTCGCGGTCCTGCGCGGTTTCGGACCGGTCTTCGCGCTGCTGTTCGGCCTTCAATTCATCTCCATGGG
CGCCATGGAGATGAACGGTCCCTTCTGGCCGATTCAGATCAAGGCATTGAGCCCCTCGGACAGCGTCTTTGGCCTCGCGG
GTATCGGCGTCTACGTCTGCCCGATGCTCGGCGTGTCGCTGACGAGTGCCTTTTGGGGACGTATGGGCGACCGGTACGGC
AATCGCCTGATGATGGTCCGGGCCTTGCTGGGCCTGGCGATCACGCAACTGCTCGTCGCCTTCGCCCAGGATGTCTGGAC
CATTCTGGCGTTGCGCTTTCTGCAGGGGGCCTGCGCTGGCTATATCGCTCCGGCCCAGGCCTACGGCGTTGAGGTCACCG
GCGGGCGCGATCGCGCCCGCCTCTTCGCCTGGCTGCAGGTGGCGACGAATGTCGGCTCCCTGGGCGGCGCTTTCCTCGGC
GGGCTCATCCTCGACGCCTTGCCTTTTGCGGCCGTCAACCTCACCGCCGGGGTGATCTGCGCATTCTGTGCCGCAGTCGC
CTGGACAAGCCTGCCGGTTCCACTAGGAGGAGCGGGACTCACGAAAACCGCGAAAGCAACAACAGTCTCTTGCGCGCCTT
CCACGGGGGTGTCCGTGTTCGGACTACTTGCTCTGATGGGATTGCTGCTTGCGAGCAGGATGGTGCTGCAGGTGCCCTTT
TCCCTCTATATGTCGGAGGTCTACGGCTCTCAGCATTGGATCACGGGATTGAGCTATGGCCTTCTTGCGCTCGGCTTTGT
GGTCGCAGCGCCGGTGTGGGCCCGGACCTTCGAAGGGCGAGAGCCGTCTTTTGTGCTCGGATGTAACGTGCTGATCGCTG
GCGGATGCTTCGTCGCCACCGGGCTCGCTGGCTCGACCCGTGCGATAGGGCTGTTCGCAGCGCTCTATTTTACCTGGGGC
GCGCTGCTTGGAGGAACGACACCGGTTCTCCTGTCGCTCGTCTCGGCCGCGACGCGAAGCGAAAGGCAGGGATCGGTCCT
GGGGCTTGCGCAGACCTGCCAGCAGGGCGCTTCGGTCGTCGGGATCATTGCAGGAGTCGCCGCCACGCAACGGTTTGGGC
TCAAGGCAGCTTTCCCGCTCGTCACGGGCCTCTACGGCCTGTCTTTTCTCGTGGCGCTCGGCCTGTGGCTGAAGGCGCGC
CAATCACGTCGCTAA

Upstream 100 bases:

>100_bases
AACGGCCCTGGCCGGCACGCTCGGTCCTGCGGATGCATCTCGAGCGCTATCGCGACTACCGCATCGAGCACCAATTGCCC
AATCCGTTGGCGAGTGCGGA

Downstream 100 bases:

>100_bases
AGAAGAAATATCGTGTTGAAACATTGTCTCTTGGCGCGTGCCATGTTGACAGCTGTTGTCTCTATCATCCTGGATCTGTC
AACGGCCTTCGCCAGCGACG

Product: MFS transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTRTVAVLRGFGPVFALLFGLQFISMGAMEMNGPFWPIQIKALSPSDSVFGLAGIGVYVCPMLGVSLTSAFWGRMGDRYG
NRLMMVRALLGLAITQLLVAFAQDVWTILALRFLQGACAGYIAPAQAYGVEVTGGRDRARLFAWLQVATNVGSLGGAFLG
GLILDALPFAAVNLTAGVICAFCAAVAWTSLPVPLGGAGLTKTAKATTVSCAPSTGVSVFGLLALMGLLLASRMVLQVPF
SLYMSEVYGSQHWITGLSYGLLALGFVVAAPVWARTFEGREPSFVLGCNVLIAGGCFVATGLAGSTRAIGLFAALYFTWG
ALLGGTTPVLLSLVSAATRSERQGSVLGLAQTCQQGASVVGIIAGVAATQRFGLKAAFPLVTGLYGLSFLVALGLWLKAR
QSRR

Sequences:

>Translated_404_residues
MTRTVAVLRGFGPVFALLFGLQFISMGAMEMNGPFWPIQIKALSPSDSVFGLAGIGVYVCPMLGVSLTSAFWGRMGDRYG
NRLMMVRALLGLAITQLLVAFAQDVWTILALRFLQGACAGYIAPAQAYGVEVTGGRDRARLFAWLQVATNVGSLGGAFLG
GLILDALPFAAVNLTAGVICAFCAAVAWTSLPVPLGGAGLTKTAKATTVSCAPSTGVSVFGLLALMGLLLASRMVLQVPF
SLYMSEVYGSQHWITGLSYGLLALGFVVAAPVWARTFEGREPSFVLGCNVLIAGGCFVATGLAGSTRAIGLFAALYFTWG
ALLGGTTPVLLSLVSAATRSERQGSVLGLAQTCQQGASVVGIIAGVAATQRFGLKAAFPLVTGLYGLSFLVALGLWLKAR
QSRR
>Mature_403_residues
TRTVAVLRGFGPVFALLFGLQFISMGAMEMNGPFWPIQIKALSPSDSVFGLAGIGVYVCPMLGVSLTSAFWGRMGDRYGN
RLMMVRALLGLAITQLLVAFAQDVWTILALRFLQGACAGYIAPAQAYGVEVTGGRDRARLFAWLQVATNVGSLGGAFLGG
LILDALPFAAVNLTAGVICAFCAAVAWTSLPVPLGGAGLTKTAKATTVSCAPSTGVSVFGLLALMGLLLASRMVLQVPFS
LYMSEVYGSQHWITGLSYGLLALGFVVAAPVWARTFEGREPSFVLGCNVLIAGGCFVATGLAGSTRAIGLFAALYFTWGA
LLGGTTPVLLSLVSAATRSERQGSVLGLAQTCQQGASVVGIIAGVAATQRFGLKAAFPLVTGLYGLSFLVALGLWLKARQ
SRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI1787291, Length=399, Percent_Identity=22.3057644110276, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4XM_RHISN (P55705)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_444149.1
- ProteinModelPortal:   P55705
- GeneID:   962496
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a00760
- HOGENOM:   HBG361240
- ProtClustDB:   CLSK809022
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 42014; Mature: 41883

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xae7d638)-; HASH(0xb388ef4)-; HASH(0xb3b4cc0)-; HASH(0xb3a9604)-; HASH(0xb44ae30)-; HASH(0xb36edf0)-; HASH(0xb39b9dc)-; HASH(0xb3bee50)-; HASH(0xbc42328)-; HASH(0xbc5b108)-; HASH(0xb01a620)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTVAVLRGFGPVFALLFGLQFISMGAMEMNGPFWPIQIKALSPSDSVFGLAGIGVYVC
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCCCCCHHHHHHHHHHH
PMLGVSLTSAFWGRMGDRYGNRLMMVRALLGLAITQLLVAFAQDVWTILALRFLQGACAG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YIAPAQAYGVEVTGGRDRARLFAWLQVATNVGSLGGAFLGGLILDALPFAAVNLTAGVIC
CCCCHHHCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFCAAVAWTSLPVPLGGAGLTKTAKATTVSCAPSTGVSVFGLLALMGLLLASRMVLQVPF
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLYMSEVYGSQHWITGLSYGLLALGFVVAAPVWARTFEGREPSFVLGCNVLIAGGCFVAT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCHHHHH
GLAGSTRAIGLFAALYFTWGALLGGTTPVLLSLVSAATRSERQGSVLGLAQTCQQGASVV
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCHHH
GIIAGVAATQRFGLKAAFPLVTGLYGLSFLVALGLWLKARQSRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TRTVAVLRGFGPVFALLFGLQFISMGAMEMNGPFWPIQIKALSPSDSVFGLAGIGVYVC
CCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCCCCCHHHHHHHHHHH
PMLGVSLTSAFWGRMGDRYGNRLMMVRALLGLAITQLLVAFAQDVWTILALRFLQGACAG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YIAPAQAYGVEVTGGRDRARLFAWLQVATNVGSLGGAFLGGLILDALPFAAVNLTAGVIC
CCCCHHHCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFCAAVAWTSLPVPLGGAGLTKTAKATTVSCAPSTGVSVFGLLALMGLLLASRMVLQVPF
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLYMSEVYGSQHWITGLSYGLLALGFVVAAPVWARTFEGREPSFVLGCNVLIAGGCFVAT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHCCCHHHHH
GLAGSTRAIGLFAALYFTWGALLGGTTPVLLSLVSAATRSERQGSVLGLAQTCQQGASVV
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHCCCHHHHHHHHHCCCHHH
GIIAGVAATQRFGLKAAFPLVTGLYGLSFLVALGLWLKARQSRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424