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Identifier: 16520002

GI number: 16520002

Start: 127018

End: 128361

Strand: Reverse

Name: Not Available

Synonym: NGR_a01030

Alternate gene names: NA

Gene position: 128361-127018 (Counterclockwise)

Preceding gene: 16520001

Following gene: 16520003

Centisome position: 23.94

GC content: 60.12

Gene sequence:

>1344_bases
ATGATATCGTTCAGCCGACTGCGCATCGGGGCCAAGCCCTCACTCGTCGTGGCATGCATATTGCTGGGCCTTGCCGCGTG
TCCAGCGCTTGCGGGCATGGCCATAGAGGAGGTCGAGACATCGAGCGGGATAAAGGCGTGGCTGGTGCAGGACTATTCGC
TACCGATCGTCACCACCCGCTTCGCATTTCGGGGCGGCAGGACGCAGGATCCATCTGGGAAGGAAGGCATTGTGAATCTG
ATCACAGAGCTGTTGGACGAAGGGGCCGGTAATCTTGACAGCGATGCCTTTCAGGAGCGGCTGGACGATGCTGGCGCCGA
GATGCTCTTTGAGGCGGGGCCCGATGCAGTCTACGGCAATATGCGGGTGCTTGCGGAGCGAAAGGATGAGGCTTTCCAAC
TTCTCCGGCTGGCAATCGAGCAGCCGCGCTTCGACCAACAGCCGGTGGACCGCCTTCGTGCCCAAATCGTCTCCAGCATC
CTGGCAAGAGCCAAGGATCCGGAGACGGCCGCACAGTTCGCATGGATGAGGGCGATCTATGGTGATCATCCGTATTCGCG
TCGGGAGGAGGGCACCGTGCAAACACTTGCCGCTGTCACGACCTCCGATCTGAAGGCGGTTCATGAGCGGATTTTCGCGC
GCGGCAACCTTACCATTGCCGTGGTGGGAGCGATCGATCCCGGCACACTCAAGCGTGATCTGGATCGAATATTCGGCGGA
TTGCCTGCTGGCCCCTCCCTAACGCCGGTCGTTGACGCAGTGCCTAAGCTGGGGCGCGCCATTCGCGTCGCGTATGACTT
ACCTCAGGCCCAACTGAGCCTAGCTTACCCGGGAATCCCCCGAAAGGACCCGCAGTTCTTTGCAGCCAATCTCATGAACC
AAATCCTTGGCGGAGGCGCGTTCACATCCAGGCTCTGGAATGAGGTGCGCGAGAAGCGGGGCCTCGCTTACGGCATTTAC
TCAACCTTGGAGAACATCGACCATGCTTCGGCGCTCGTCATCGGCACCGGAACCCGCCCGGATCGGGCCGCAGAGACGCT
CTCCCTCATCCAAGCCGAGGTCAGGCGAATGTCAGAGGAGGGCGTCAGTGAGGACGAGCTCACTGCGGCAAAGAAAAAGC
TCATCGGCGGTTATGCGATCGAAAATCTGAACTCATCTAGTGCGGTCGCCCAAACATTGGTCCAAATCCAACTCGAAGAT
CGCGGCATCGAGTACGTCGAGCGCCGCAAACAACTGATCCAGGCCGTCACCGTGGAGGACGTACGGGCAGTCGCGAAACG
GCTGCTCTCCGCCGACCCCACCGTAATGACTGTTGGACCGTCCCTCAAGGGAACGAACCGATGA

Upstream 100 bases:

>100_bases
CAGAGGTGCAAGCGGCTGCCAGGAAATACCTCAGTCCCGACCGGTCCGTAGCGGGGTATCTGCTGCCCCGCGAAAGCGCT
ACCTCAGGAGATAAAAGCCG

Downstream 100 bases:

>100_bases
CCGTCCAAAGGAAAGCTAGGCTGGCAGCGTCCGGCCGACCTTCTCCAACGCCCCGGCGCGGCACTACCTTGGGAGGGGGG
TAGTCAAGATCACCTCTCGC

Product: Zn-dependent protease, M16 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MISFSRLRIGAKPSLVVACILLGLAACPALAGMAIEEVETSSGIKAWLVQDYSLPIVTTRFAFRGGRTQDPSGKEGIVNL
ITELLDEGAGNLDSDAFQERLDDAGAEMLFEAGPDAVYGNMRVLAERKDEAFQLLRLAIEQPRFDQQPVDRLRAQIVSSI
LARAKDPETAAQFAWMRAIYGDHPYSRREEGTVQTLAAVTTSDLKAVHERIFARGNLTIAVVGAIDPGTLKRDLDRIFGG
LPAGPSLTPVVDAVPKLGRAIRVAYDLPQAQLSLAYPGIPRKDPQFFAANLMNQILGGGAFTSRLWNEVREKRGLAYGIY
STLENIDHASALVIGTGTRPDRAAETLSLIQAEVRRMSEEGVSEDELTAAKKKLIGGYAIENLNSSSAVAQTLVQIQLED
RGIEYVERRKQLIQAVTVEDVRAVAKRLLSADPTVMTVGPSLKGTNR

Sequences:

>Translated_447_residues
MISFSRLRIGAKPSLVVACILLGLAACPALAGMAIEEVETSSGIKAWLVQDYSLPIVTTRFAFRGGRTQDPSGKEGIVNL
ITELLDEGAGNLDSDAFQERLDDAGAEMLFEAGPDAVYGNMRVLAERKDEAFQLLRLAIEQPRFDQQPVDRLRAQIVSSI
LARAKDPETAAQFAWMRAIYGDHPYSRREEGTVQTLAAVTTSDLKAVHERIFARGNLTIAVVGAIDPGTLKRDLDRIFGG
LPAGPSLTPVVDAVPKLGRAIRVAYDLPQAQLSLAYPGIPRKDPQFFAANLMNQILGGGAFTSRLWNEVREKRGLAYGIY
STLENIDHASALVIGTGTRPDRAAETLSLIQAEVRRMSEEGVSEDELTAAKKKLIGGYAIENLNSSSAVAQTLVQIQLED
RGIEYVERRKQLIQAVTVEDVRAVAKRLLSADPTVMTVGPSLKGTNR
>Mature_447_residues
MISFSRLRIGAKPSLVVACILLGLAACPALAGMAIEEVETSSGIKAWLVQDYSLPIVTTRFAFRGGRTQDPSGKEGIVNL
ITELLDEGAGNLDSDAFQERLDDAGAEMLFEAGPDAVYGNMRVLAERKDEAFQLLRLAIEQPRFDQQPVDRLRAQIVSSI
LARAKDPETAAQFAWMRAIYGDHPYSRREEGTVQTLAAVTTSDLKAVHERIFARGNLTIAVVGAIDPGTLKRDLDRIFGG
LPAGPSLTPVVDAVPKLGRAIRVAYDLPQAQLSLAYPGIPRKDPQFFAANLMNQILGGGAFTSRLWNEVREKRGLAYGIY
STLENIDHASALVIGTGTRPDRAAETLSLIQAEVRRMSEEGVSEDELTAAKKKLIGGYAIENLNSSSAVAQTLVQIQLED
RGIEYVERRKQLIQAVTVEDVRAVAKRLLSADPTVMTVGPSLKGTNR

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4WB_RHISN (P55680)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_444122.1
- ProteinModelPortal:   P55680
- GeneID:   962461
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a01030
- HOGENOM:   HBG642219
- ProtClustDB:   CLSK864943
- GO:   GO:0006508
- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR007863
- Gene3D:   G3DSA:3.30.830.10

Pfam domain/function: PF05193 Peptidase_M16_C; SSF63411 Metalloenz_metal-bd

EC number: NA

Molecular weight: Translated: 48525; Mature: 48525

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00143 INSULINASE; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFSRLRIGAKPSLVVACILLGLAACPALAGMAIEEVETSSGIKAWLVQDYSLPIVTTR
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCEEEEH
FAFRGGRTQDPSGKEGIVNLITELLDEGAGNLDSDAFQERLDDAGAEMLFEAGPDAVYGN
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHCC
MRVLAERKDEAFQLLRLAIEQPRFDQQPVDRLRAQIVSSILARAKDPETAAQFAWMRAIY
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GDHPYSRREEGTVQTLAAVTTSDLKAVHERIFARGNLTIAVVGAIDPGTLKRDLDRIFGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCC
LPAGPSLTPVVDAVPKLGRAIRVAYDLPQAQLSLAYPGIPRKDPQFFAANLMNQILGGGA
CCCCCCCCHHHHHHHHHHHHEEHHHCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHCCHH
FTSRLWNEVREKRGLAYGIYSTLENIDHASALVIGTGTRPDRAAETLSLIQAEVRRMSEE
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
GVSEDELTAAKKKLIGGYAIENLNSSSAVAQTLVQIQLEDRGIEYVERRKQLIQAVTVED
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VRAVAKRLLSADPTVMTVGPSLKGTNR
HHHHHHHHHCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MISFSRLRIGAKPSLVVACILLGLAACPALAGMAIEEVETSSGIKAWLVQDYSLPIVTTR
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCEEEEH
FAFRGGRTQDPSGKEGIVNLITELLDEGAGNLDSDAFQERLDDAGAEMLFEAGPDAVYGN
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHCC
MRVLAERKDEAFQLLRLAIEQPRFDQQPVDRLRAQIVSSILARAKDPETAAQFAWMRAIY
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GDHPYSRREEGTVQTLAAVTTSDLKAVHERIFARGNLTIAVVGAIDPGTLKRDLDRIFGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCC
LPAGPSLTPVVDAVPKLGRAIRVAYDLPQAQLSLAYPGIPRKDPQFFAANLMNQILGGGA
CCCCCCCCHHHHHHHHHHHHEEHHHCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHCCHH
FTSRLWNEVREKRGLAYGIYSTLENIDHASALVIGTGTRPDRAAETLSLIQAEVRRMSEE
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
GVSEDELTAAKKKLIGGYAIENLNSSSAVAQTLVQIQLEDRGIEYVERRKQLIQAVTVED
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VRAVAKRLLSADPTVMTVGPSLKGTNR
HHHHHHHHHCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424