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Identifier: 16519870

GI number: 16519870

Start: 306500

End: 307690

Strand: Reverse

Name: Not Available

Synonym: NGR_a02350

Alternate gene names: 16519870

Gene position: 307690-306500 (Counterclockwise)

Preceding gene: 16519869

Following gene: 16519871

Centisome position: 57.39

GC content: 51.55

Gene sequence:

>1191_bases
ATGGTGAAGAACTTCCTTGGATCATCGGTTACATCAGGCTCGGCTGGAGCGGAACATGGAAAGACTTTGCAAATTCCGAC
TTTACGATGGGTGCGCCAGTCGAAGACTTCGATCATGGCACTTGTAATTTGTCTAGGCAGGATAGTGAAAACAGCACTCG
TTACCGGCGGCTCCGGATATTTTGGGGAACTGTTAAGCAAGCAATTGCTTAGACAAGGAACCTACGTTCGCGTGTTCGAC
CTGAATCCGCCCGGCTTCAGTCATCCTAATCTTGAATTTCTCAAGGGCACAATTCTCGACCGAAACGCGGTCAGACAAGC
ACTTTCCGGGATAGACAAGGTGTTCCACAACGTTGCGCAGGTACCGCTAGCCAAGGAAAAAGACCTATTCTGGTCCGTTA
ACTGCGGAGGCACTCAGATCATCGTTGACGAGTCGGTCGCGACGGGGATCGAAAAGTTCGTCTACACGTCCTCGAGCGCT
GTTTTCGGTGCGCCGAAATCGAACCCCGTAACAGAAGAAACAGAACCGAACCCGGCGGAAGATTATGGTCGCGCGAAACT
CGCAGGAGAAATTATCTGTAAGGAAGCAATGCAGCGTGATGGCTTGGATGTGGCGATTGTGCGCCCTCGCACAGTTCTCG
GATATGGCCGCCAAGGCGTCGTCCAGATTCTCTTTGACTGGGTTGAACGGGGGCTCGATATTCCAGTGTTGGGTGGGGGT
AATAACAAATATCAGTTCGTGCACTCGGATGATTTAGCATCGGCATGCATAGCAGCCTCGAATGTAAAGGGGTTTGCCAC
ATACAATATTGGTGCTGCCGAGTTCGGTACGATGCGTGAACTTTTGCAAGTGGTAATCAAGCATGCCGAAACCGGAAGTC
GAATCAAATCGATCCCGATGGGACCGACTGCCCTTGCAGCGAATCTGGCAAGCGCGCTCGGCCTCTCTCCCTTAGGGCCA
TACCATTCGCTGATGTATGGGAGAGCAATGTATTTCGATATCTCCAAAGCGCAAAAGGAACTTGGGTATGCACCGAGATA
CTCTAATTCTCAGATGATGATCGAGACCTATAATTGGTACCAGGCTAATAGGGCTTCTCTCGGAAAAGGCGGAGGGTCAC
GTCATAAGGCGCCCGTCAAACAGCAGCTCCTGGCATTGCTTCCCTATGCACTGCGGCTGATCCCAGGATGA

Upstream 100 bases:

>100_bases
GAAGTGATCGCGTTGCTTTGGAACGATTTTCAAGCTTGGCACGACACATGCATAGCCATCCACATACACGCTGCGCCGCC
GCGCTGGAGATTCCGAAGCA

Downstream 100 bases:

>100_bases
ACGCGGTTCCGATAATCTTGGTTTTTGCTGCGGGCCTGAATTCCTGTATTGGCAATATATTGCTGAAATGGGGCCGGGCC
TCACTGCCTCCCAGCGCCGG

Product: nucleotide sugar epimerase/dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MVKNFLGSSVTSGSAGAEHGKTLQIPTLRWVRQSKTSIMALVICLGRIVKTALVTGGSGYFGELLSKQLLRQGTYVRVFD
LNPPGFSHPNLEFLKGTILDRNAVRQALSGIDKVFHNVAQVPLAKEKDLFWSVNCGGTQIIVDESVATGIEKFVYTSSSA
VFGAPKSNPVTEETEPNPAEDYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQGVVQILFDWVERGLDIPVLGGG
NNKYQFVHSDDLASACIAASNVKGFATYNIGAAEFGTMRELLQVVIKHAETGSRIKSIPMGPTALAANLASALGLSPLGP
YHSLMYGRAMYFDISKAQKELGYAPRYSNSQMMIETYNWYQANRASLGKGGGSRHKAPVKQQLLALLPYALRLIPG

Sequences:

>Translated_396_residues
MVKNFLGSSVTSGSAGAEHGKTLQIPTLRWVRQSKTSIMALVICLGRIVKTALVTGGSGYFGELLSKQLLRQGTYVRVFD
LNPPGFSHPNLEFLKGTILDRNAVRQALSGIDKVFHNVAQVPLAKEKDLFWSVNCGGTQIIVDESVATGIEKFVYTSSSA
VFGAPKSNPVTEETEPNPAEDYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQGVVQILFDWVERGLDIPVLGGG
NNKYQFVHSDDLASACIAASNVKGFATYNIGAAEFGTMRELLQVVIKHAETGSRIKSIPMGPTALAANLASALGLSPLGP
YHSLMYGRAMYFDISKAQKELGYAPRYSNSQMMIETYNWYQANRASLGKGGGSRHKAPVKQQLLALLPYALRLIPG
>Mature_396_residues
MVKNFLGSSVTSGSAGAEHGKTLQIPTLRWVRQSKTSIMALVICLGRIVKTALVTGGSGYFGELLSKQLLRQGTYVRVFD
LNPPGFSHPNLEFLKGTILDRNAVRQALSGIDKVFHNVAQVPLAKEKDLFWSVNCGGTQIIVDESVATGIEKFVYTSSSA
VFGAPKSNPVTEETEPNPAEDYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQGVVQILFDWVERGLDIPVLGGG
NNKYQFVHSDDLASACIAASNVKGFATYNIGAAEFGTMRELLQVVIKHAETGSRIKSIPMGPTALAANLASALGLSPLGP
YHSLMYGRAMYFDISKAQKELGYAPRYSNSQMMIETYNWYQANRASLGKGGGSRHKAPVKQQLLALLPYALRLIPG

Specific function: Putative nucleotide sugar epimerase/dehydrogenase

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI193211614, Length=335, Percent_Identity=25.6716417910448, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI8393516, Length=335, Percent_Identity=25.6716417910448, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310132178, Length=342, Percent_Identity=25.4385964912281, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI310113012, Length=342, Percent_Identity=25.4385964912281, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI239745448, Length=342, Percent_Identity=25.4385964912281, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI116268111, Length=359, Percent_Identity=27.0194986072423, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI87081792, Length=327, Percent_Identity=23.8532110091743, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786974, Length=351, Percent_Identity=25.0712250712251, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321437, Length=342, Percent_Identity=23.3918128654971, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y4NG_RHISN (P55579)

Other databases:

- EMBL:   U00090
- RefSeq:   NP_443990.1
- ProteinModelPortal:   P55579
- GeneID:   962378
- GenomeReviews:   U00090_GR
- KEGG:   rhi:NGR_a02350
- HOGENOM:   HBG403426
- ProtClustDB:   CLSK2459732
- InterPro:   IPR001509
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01370 Epimerase

EC number: NA

Molecular weight: Translated: 42843; Mature: 42843

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKNFLGSSVTSGSAGAEHGKTLQIPTLRWVRQSKTSIMALVICLGRIVKTALVTGGSGY
CCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
FGELLSKQLLRQGTYVRVFDLNPPGFSHPNLEFLKGTILDRNAVRQALSGIDKVFHNVAQ
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VPLAKEKDLFWSVNCGGTQIIVDESVATGIEKFVYTSSSAVFGAPKSNPVTEETEPNPAE
CCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHEECCCEEECCCCCCCCCCCCCCCCHH
DYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQGVVQILFDWVERGLDIPVLGGG
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCHHHHHHHHHHHHCCCCEEEECCC
NNKYQFVHSDDLASACIAASNVKGFATYNIGAAEFGTMRELLQVVIKHAETGSRIKSIPM
CCCEEEEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCC
GPTALAANLASALGLSPLGPYHSLMYGRAMYFDISKAQKELGYAPRYSNSQMMIETYNWY
CHHHHHHHHHHHHCCCCCCHHHHHHHCCHHEEEHHHHHHHCCCCCCCCCCEEEEEECCCH
QANRASLGKGGGSRHKAPVKQQLLALLPYALRLIPG
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKNFLGSSVTSGSAGAEHGKTLQIPTLRWVRQSKTSIMALVICLGRIVKTALVTGGSGY
CCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
FGELLSKQLLRQGTYVRVFDLNPPGFSHPNLEFLKGTILDRNAVRQALSGIDKVFHNVAQ
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VPLAKEKDLFWSVNCGGTQIIVDESVATGIEKFVYTSSSAVFGAPKSNPVTEETEPNPAE
CCCCCCCCCEEEECCCCEEEEEECHHHHHHHHHHEECCCEEECCCCCCCCCCCCCCCCHH
DYGRAKLAGEIICKEAMQRDGLDVAIVRPRTVLGYGRQGVVQILFDWVERGLDIPVLGGG
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCHHHHHHHHHHHHCCCCEEEECCC
NNKYQFVHSDDLASACIAASNVKGFATYNIGAAEFGTMRELLQVVIKHAETGSRIKSIPM
CCCEEEEECCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCC
GPTALAANLASALGLSPLGPYHSLMYGRAMYFDISKAQKELGYAPRYSNSQMMIETYNWY
CHHHHHHHHHHHHCCCCCCHHHHHHHCCHHEEEHHHHHHHCCCCCCCCCCEEEEEECCCH
QANRASLGKGGGSRHKAPVKQQLLALLPYALRLIPG
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424