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The map label for this gene is lptA

Identifier: 16273644

GI number: 16273644

Start: 1217672

End: 1218190

Strand: Reverse

Name: lptA

Synonym: HI1149m

Alternate gene names: 16273644

Gene position: 1218190-1217672 (Counterclockwise)

Preceding gene: 30995426

Following gene: 16273074

Centisome position: 66.56

GC content: 33.72

Gene sequence:

>519_bases
ATGAAGTTAGTAAGCAATAAAATTCTTTTTCTTGCAACGATGGTATTAGCATCAAGTTCAGCTTTTGCATTGAAAGATGA
TGTTAATCAGCCGATAAATATTGTTTCGGATAATCAATCCTTAGATATGGAAAAAAGTGTAGTGACATTCACAGATAATG
TGGTAATTACACAGGGGTCTATTGTTATCAAAGCAAATAAAGTTGTCATCACTCGTCCTGCTGAAAAATCAGGGAAAAAA
GAAACCGTAGAAGCATTCGGCACGCCAGTCACATTCCATCAACAGTTAGATAATGGTAAGCCAGTGGATGGAAAAGCAAA
TAAAGTTCATTATGATCTTGGTAACGAATTTTTAACATTAACTAACAATGCCGAATTAAAGCAGCTTGATAGTAAAATTA
ATGGCAGTGTTATTACCTATGATGTGAAAAAACAACAACTTAAAGCTAATGGTAATGGAAAATCACGAGTAACAACAGTT
CTTATTCCATCTCAATTACAACAAGCTAAAGGGAAGTAA

Upstream 100 bases:

>100_bases
GTTAAAATTAAGGGTAAAAATTTTAGTTCTACAGGATTAAAATTAGTCGGAAATTTACGCCAACAAGTGGCGACATTAAA
GGAACAGGTAAAAACATATT

Downstream 100 bases:

>100_bases
TCTATGTCAATTTTGACTGCAGAGAATTTAGCTAAAAGCTACAAAAGTCGTAAAGTTGTTTCGGATGTTAGTTTAACCGT
AAATTCTAATGAAATTGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKLVSNKILFLATMVLASSSAFALKDDVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGSIVIKANKVVITRPAEKSGKK
ETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTLTNNAELKQLDSKINGSVITYDVKKQQLKANGNGKSRVTTV
LIPSQLQQAKGK

Sequences:

>Translated_172_residues
MKLVSNKILFLATMVLASSSAFALKDDVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGSIVIKANKVVITRPAEKSGKK
ETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTLTNNAELKQLDSKINGSVITYDVKKQQLKANGNGKSRVTTV
LIPSQLQQAKGK
>Mature_172_residues
MKLVSNKILFLATMVLASSSAFALKDDVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGSIVIKANKVVITRPAEKSGKK
ETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTLTNNAELKQLDSKINGSVITYDVKKQQLKANGNGKSRVTTV
LIPSQLQQAKGK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family

Homologues:

Organism=Escherichia coli, GI1789592, Length=171, Percent_Identity=53.8011695906433, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTA_HAEIN (P45074)

Other databases:

- EMBL:   L42023
- PIR:   A64168
- RefSeq:   NP_439307.1
- ProteinModelPortal:   P45074
- SMR:   P45074
- GeneID:   950113
- GenomeReviews:   L42023_GR
- NMPDR:   fig|71421.1.peg.1102
- TIGR:   HI_1149
- HOGENOM:   HBG701445
- OMA:   VTFTDNV
- ProtClustDB:   CLSK869994
- BioCyc:   HINF71421:HI_1149-MONOMER
- GO:   GO:0006810
- InterPro:   IPR014340
- InterPro:   IPR005653
- TIGRFAMs:   TIGR03002

Pfam domain/function: PF03968 OstA

EC number: NA

Molecular weight: Translated: 18701; Mature: 18701

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVSNKILFLATMVLASSSAFALKDDVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGS
CCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCCCCCEEEEEECCEEEECCE
IVIKANKVVITRPAEKSGKKETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTL
EEEEECEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEE
TNNAELKQLDSKINGSVITYDVKKQQLKANGNGKSRVTTVLIPSQLQQAKGK
ECCCHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEEEEEECHHHHHHCCC
>Mature Secondary Structure
MKLVSNKILFLATMVLASSSAFALKDDVNQPINIVSDNQSLDMEKSVVTFTDNVVITQGS
CCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCCCCCEEEEEECCEEEECCE
IVIKANKVVITRPAEKSGKKETVEAFGTPVTFHQQLDNGKPVDGKANKVHYDLGNEFLTL
EEEEECEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEE
TNNAELKQLDSKINGSVITYDVKKQQLKANGNGKSRVTTVLIPSQLQQAKGK
ECCCHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEEEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023