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The map label for this gene is tehB

Identifier: 16273190

GI number: 16273190

Start: 1350886

End: 1351746

Strand: Reverse

Name: tehB

Synonym: HI1275

Alternate gene names: 16273190

Gene position: 1351746-1350886 (Counterclockwise)

Preceding gene: 16273191

Following gene: 16273184

Centisome position: 73.86

GC content: 36.12

Gene sequence:

>861_bases
ATGAAAAACGAATTAATTTGCTATAAACAAATGCCAGTGTGGACAAAAGACAACTTGCCACAAATGTTCCAAGAAAAGCA
CAATACAAAAGTCGGCACTTGGGGAAAATTAACTGTATTAAAAGGTAAGCTTAAATTTTATGAGCTAACCGAAAATGGCG
ATGTTATTGCCGAGCATATTTTTACCCCAGAAAGCCACATTCCTTTTGTTGAACCTCAAGCATGGCATCGTGTAGAAGCA
CTTTCTGATGACCTAGAATGTACCCTAGGTTTCTATTGCAAAAAAGAAGATTATTTCAGTAAAAAATACAACACGACTGC
CATTCACGGCGATGTGGTGGATGCTGCAAAAATTATCTCGCCTTGTAAAGTATTAGATTTAGGTTGCGGACAAGGGCGTA
ATTCACTTTATTTAAGTTTATTAGGCTATGATGTGACCTCTTGGGATCACAATGAAAACAGCATTGCCTTTTTAAATGAA
ACTAAAGAGAAAGAAAATCTTAATATTTCTACCGCACTTTACGACATTAACGCCGCCAACATTCAAGAAAACTATGATTT
TATTGTTTCAACGGTGGTATTTATGTTCTTAAATCGTGAACGTGTGCCATCAATCATTAAAAATATGAAAGAACATACCA
ATGTTGGCGGGTATAACTTAATCGTTGCCGCCATGTCCACAGATGATGTGCCTTGCCCACTTCCATTCTCTTTCACTTTT
GCTGAAAACGAATTGAAAGAATATTACAAAGATTGGGAATTCTTAGAATATAACGAAAATATGGGCGAATTACACAAAAC
CGATGAAAACGGCAATCGCATTAAAATGAAATTTGCCACCATGTTAGCGAGAAAGAAATAA

Upstream 100 bases:

>100_bases
AAATGAGGGCAACATTACGTTGCCTTTTTATTTTCTTGTTGAAAATAGATGACTTATAACCTACCATAACACTCAACTAT
TTATCTATTTGGAGAATACT

Downstream 100 bases:

>100_bases
TCTGCTAATTTAAAAAATCACCGCACTTTGTGCTCCCCCCCAATAAAAAGATAACTTAGAAAATATCTTTGGCTTTACGA
AGTGCGGTAAATTCTTCAAG

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNELICYKQMPVWTKDNLPQMFQEKHNTKVGTWGKLTVLKGKLKFYELTENGDVIAEHIFTPESHIPFVEPQAWHRVEA
LSDDLECTLGFYCKKEDYFSKKYNTTAIHGDVVDAAKIISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNE
TKEKENLNISTALYDINAANIQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPFSFTF
AENELKEYYKDWEFLEYNENMGELHKTDENGNRIKMKFATMLARKK

Sequences:

>Translated_286_residues
MKNELICYKQMPVWTKDNLPQMFQEKHNTKVGTWGKLTVLKGKLKFYELTENGDVIAEHIFTPESHIPFVEPQAWHRVEA
LSDDLECTLGFYCKKEDYFSKKYNTTAIHGDVVDAAKIISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNE
TKEKENLNISTALYDINAANIQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPFSFTF
AENELKEYYKDWEFLEYNENMGELHKTDENGNRIKMKFATMLARKK
>Mature_286_residues
MKNELICYKQMPVWTKDNLPQMFQEKHNTKVGTWGKLTVLKGKLKFYELTENGDVIAEHIFTPESHIPFVEPQAWHRVEA
LSDDLECTLGFYCKKEDYFSKKYNTTAIHGDVVDAAKIISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNE
TKEKENLNISTALYDINAANIQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPFSFTF
AENELKEYYKDWEFLEYNENMGELHKTDENGNRIKMKFATMLARKK

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm. Note=Probably a peripheral membrane protein that interacts with TehA (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family

Homologues:

Organism=Escherichia coli, GI1787700, Length=194, Percent_Identity=55.1546391752577, Blast_Score=225, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TEHB_HAEIN (P45134)

Other databases:

- EMBL:   L42023
- PIR:   H64113
- RefSeq:   NP_439428.1
- PDB:   3M70
- PDBsum:   3M70
- ProteinModelPortal:   P45134
- SMR:   P45134
- GeneID:   949980
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1275
- NMPDR:   fig|71421.1.peg.1217
- TIGR:   HI_1275
- HOGENOM:   HBG296629
- OMA:   IPFVEPQ
- ProtClustDB:   PRK12335
- BioCyc:   HINF71421:HI_1275-MONOMER
- GO:   GO:0005737
- InterPro:   IPR015392
- InterPro:   IPR014710
- InterPro:   IPR004537
- InterPro:   IPR014431
- InterPro:   IPR015985
- Gene3D:   G3DSA:2.60.120.10
- PIRSF:   PIRSF005215
- TIGRFAMs:   TIGR00477

Pfam domain/function: PF09313 DUF1971; PF03848 TehB

EC number: NA

Molecular weight: Translated: 33020; Mature: 33020

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNELICYKQMPVWTKDNLPQMFQEKHNTKVGTWGKLTVLKGKLKFYELTENGDVIAEHI
CCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCEEEEEE
FTPESHIPFVEPQAWHRVEALSDDLECTLGFYCKKEDYFSKKYNTTAIHGDVVDAAKIIS
CCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCCEEEECCHHHHHHHHC
PCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKEKENLNISTALYDINAAN
CHHEEECCCCCCCCEEEEEEEECEEECCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCC
IQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPFSFTF
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEE
AENELKEYYKDWEFLEYNENMGELHKTDENGNRIKMKFATMLARKK
CHHHHHHHHCCCCEEEECCCCCHHCCCCCCCCEEEEEHHHHHHCCC
>Mature Secondary Structure
MKNELICYKQMPVWTKDNLPQMFQEKHNTKVGTWGKLTVLKGKLKFYELTENGDVIAEHI
CCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCEEEEEECCCCCEEEEEE
FTPESHIPFVEPQAWHRVEALSDDLECTLGFYCKKEDYFSKKYNTTAIHGDVVDAAKIIS
CCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHCCCCCEEEECCHHHHHHHHC
PCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKEKENLNISTALYDINAAN
CHHEEECCCCCCCCEEEEEEEECEEECCCCCCCCEEEEECCCCCCCCEEEEEEEECCCCC
IQENYDFIVSTVVFMFLNRERVPSIIKNMKEHTNVGGYNLIVAAMSTDDVPCPLPFSFTF
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEEE
AENELKEYYKDWEFLEYNENMGELHKTDENGNRIKMKFATMLARKK
CHHHHHHHHCCCCEEEECCCCCHHCCCCCCCCEEEEEHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800