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The map label for this gene is yfcB [C]

Identifier: 16273121

GI number: 16273121

Start: 1267077

End: 1268021

Strand: Reverse

Name: yfcB [C]

Synonym: HI1201

Alternate gene names: 16273121

Gene position: 1268021-1267077 (Counterclockwise)

Preceding gene: 16273123

Following gene: 16273115

Centisome position: 69.29

GC content: 38.41

Gene sequence:

>945_bases
ATGGAAACTTCACATAACCAAGAATTAGTTGCAACTATCTTGGAAGATAATGTTGCAAACGAACTGCAAACCATCCAAGA
TTTTCTGCGTTGGACGTATAGCATTCTCAATCGATCTGATATTTACTTCGGGCAAGGGCACGATAATCCTTGGGATGAAA
GCCTGCAACTCGTTTTAAGTAGCTTACATTTACCCATTGATTTACCTACCGAATTATTTAACAGTCGATTAACCCCATCT
GAAAAAGAAACCTTAGTTCAACTTGTATTAACCCGAATCGAACAACGCGTACCTGTGGCATATTTAACAAATAGTGCTTG
GTTCTGCGGTCACGAATTTTATGTCGATGAACGAACCATTATTCCACGTTCTCCAATTAGTGCTTTAATTCAAGATCGAT
TTGAAGATTTAATTTCACAAGAACCAAATCATATTCTCGATCTATGCACAGGCAGCGGTTGTATTGCCATTGCTTGTGCT
TATGCTTTCCCGAATGCGGAAGTAGATGCGGTAGATTTATCGGTTGATGCACTTAATGTCGCGGAGATCAATATTTCACG
CCATCAATTAGAGCATCGTGTATTCCCGATTCAATCAAACTTATTTGAAAATATTTTGGGACAAAAATACGATCTTATCG
TGACCAATCCACCTTATGTGGATGAAGAAGATCTCGCCGATATGCCAGAAGAATTCCATTTTGAACCAGAGTTAGCCTTA
GGTTCTGGCAGTGATGGCTTAAACATTACCAAACAAATTTTAAAACAAGCACCAGATTACTTAACCGAAAATGGCGTGTT
GGTGTGTGAAGTGGGTAATAGTATGATTAGCTTAATTGAGCAATATCCAGATGTACCATTTGAATGGGTAGAACTTAAAA
ATGGCGGACTAGGCGTATTTGCTATTCAGCGTAAGGATTTAGTGAAATATCACGATCTGTTTTAA

Upstream 100 bases:

>100_bases
TCATATCATAGTTCTACATTCTCATCTGTGGTATAACTACGCCAAATTTTCATACCTAATTTTATGCTAACTTTTCTACT
CACTTTTATGGAGAAATGCG

Downstream 100 bases:

>100_bases
TCTTTTAAGTGCGATTAAAATTCTTATTAAATTTCAACCGCACTTCATTTGGACATTGTTATTTTGTTTCCAATTCAATG
CCTTCAAATAATTTTTTCAC

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
METSHNQELVATILEDNVANELQTIQDFLRWTYSILNRSDIYFGQGHDNPWDESLQLVLSSLHLPIDLPTELFNSRLTPS
EKETLVQLVLTRIEQRVPVAYLTNSAWFCGHEFYVDERTIIPRSPISALIQDRFEDLISQEPNHILDLCTGSGCIAIACA
YAFPNAEVDAVDLSVDALNVAEINISRHQLEHRVFPIQSNLFENILGQKYDLIVTNPPYVDEEDLADMPEEFHFEPELAL
GSGSDGLNITKQILKQAPDYLTENGVLVCEVGNSMISLIEQYPDVPFEWVELKNGGLGVFAIQRKDLVKYHDLF

Sequences:

>Translated_314_residues
METSHNQELVATILEDNVANELQTIQDFLRWTYSILNRSDIYFGQGHDNPWDESLQLVLSSLHLPIDLPTELFNSRLTPS
EKETLVQLVLTRIEQRVPVAYLTNSAWFCGHEFYVDERTIIPRSPISALIQDRFEDLISQEPNHILDLCTGSGCIAIACA
YAFPNAEVDAVDLSVDALNVAEINISRHQLEHRVFPIQSNLFENILGQKYDLIVTNPPYVDEEDLADMPEEFHFEPELAL
GSGSDGLNITKQILKQAPDYLTENGVLVCEVGNSMISLIEQYPDVPFEWVELKNGGLGVFAIQRKDLVKYHDLF
>Mature_314_residues
METSHNQELVATILEDNVANELQTIQDFLRWTYSILNRSDIYFGQGHDNPWDESLQLVLSSLHLPIDLPTELFNSRLTPS
EKETLVQLVLTRIEQRVPVAYLTNSAWFCGHEFYVDERTIIPRSPISALIQDRFEDLISQEPNHILDLCTGSGCIAIACA
YAFPNAEVDAVDLSVDALNVAEINISRHQLEHRVFPIQSNLFENILGQKYDLIVTNPPYVDEEDLADMPEEFHFEPELAL
GSGSDGLNITKQILKQAPDYLTENGVLVCEVGNSMISLIEQYPDVPFEWVELKNGGLGVFAIQRKDLVKYHDLF

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family

Homologues:

Organism=Homo sapiens, GI7705409, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI87082085, Length=302, Percent_Identity=60.5960264900662, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1787463, Length=184, Percent_Identity=34.7826086956522, Blast_Score=105, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324266, Length=184, Percent_Identity=26.6304347826087, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582226, Length=200, Percent_Identity=24.5, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1201_HAEIN (P45106)

Other databases:

- EMBL:   L42023
- PIR:   F64189
- RefSeq:   NP_439357.1
- ProteinModelPortal:   P45106
- SMR:   P45106
- GeneID:   950156
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1201
- NMPDR:   fig|71421.1.peg.1148
- TIGR:   HI_1201
- HOGENOM:   HBG732041
- OMA:   VGNSQVH
- ProtClustDB:   PRK11805
- BioCyc:   HINF71421:HI_1201-MONOMER
- BRENDA:   2.1.1.72
- GO:   GO:0005622
- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848
- PIRSF:   PIRSF037167
- TIGRFAMs:   TIGR00536
- TIGRFAMs:   TIGR03533

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.72

Molecular weight: Translated: 35590; Mature: 35590

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSHNQELVATILEDNVANELQTIQDFLRWTYSILNRSDIYFGQGHDNPWDESLQLVLS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
SLHLPIDLPTELFNSRLTPSEKETLVQLVLTRIEQRVPVAYLTNSAWFCGHEFYVDERTI
HHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEEECCEEEECCCCC
IPRSPISALIQDRFEDLISQEPNHILDLCTGSGCIAIACAYAFPNAEVDAVDLSVDALNV
CCCCHHHHHHHHHHHHHHHCCCCCEEHHHCCCCHHEEEEEHHCCCCCCEEEEEEECEEEE
AEINISRHQLEHRVFPIQSNLFENILGQKYDLIVTNPPYVDEEDLADMPEEFHFEPELAL
EEECHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCHHHCCCCCEEE
GSGSDGLNITKQILKQAPDYLTENGVLVCEVGNSMISLIEQYPDVPFEWVELKNGGLGVF
CCCCCCCHHHHHHHHHCCHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCEEEE
AIQRKDLVKYHDLF
EECHHHHHHHHCCC
>Mature Secondary Structure
METSHNQELVATILEDNVANELQTIQDFLRWTYSILNRSDIYFGQGHDNPWDESLQLVLS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHH
SLHLPIDLPTELFNSRLTPSEKETLVQLVLTRIEQRVPVAYLTNSAWFCGHEFYVDERTI
HHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEEECCEEEECCCCC
IPRSPISALIQDRFEDLISQEPNHILDLCTGSGCIAIACAYAFPNAEVDAVDLSVDALNV
CCCCHHHHHHHHHHHHHHHCCCCCEEHHHCCCCHHEEEEEHHCCCCCCEEEEEEECEEEE
AEINISRHQLEHRVFPIQSNLFENILGQKYDLIVTNPPYVDEEDLADMPEEFHFEPELAL
EEECHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCHHHCCCCCEEE
GSGSDGLNITKQILKQAPDYLTENGVLVCEVGNSMISLIEQYPDVPFEWVELKNGGLGVF
CCCCCCCHHHHHHHHHCCHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCEEEE
AIQRKDLVKYHDLF
EECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800