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The map label for this gene is mdtA [H]

Identifier: 162149611

GI number: 162149611

Start: 3932524

End: 3933705

Strand: Direct

Name: mdtA [H]

Synonym: GDI_3850

Alternate gene names: 162149611

Gene position: 3932524-3933705 (Clockwise)

Preceding gene: 162149610

Following gene: 162149612

Centisome position: 99.7

GC content: 60.58

Gene sequence:

>1182_bases
ATGGCTTCCCTGTCACGTAATACCGTTCTGGCGACGGGGGTCTGCGCTGTGGCCCTGTTGGTCGGTTATCAGGTGGTCAC
CCGGATTCATGCGGTGACCGAACTGCGCGCGGAGACGCTTAGCAATGCGCTGCCCGATGTGGCCGTTGTCCATGCGAAAC
CTTCGCCCAAGGATGTGACCCTGACTTTGCCGGGCAATATCGATGCCTGGTATCAGGCGCCGATTTTTCCGCAGGCCTCG
GGCTACGTGAAGATGTGGTACAAGGATTACGGCGCCGAGGTGAAGACCGGCGATGTGCTGGCCGAAATCAATGCCCCAAG
CCTGGACGCGCAATATGCTCAGGCGAAGGCGGACCTGGCGGCGGCCGAAGCCAAGTACAACCTGGCTGTCGTCAGTGCCG
ATCGCTGGCATGCGATGGCGAAGTCGCAGGCCGTTTCCGGGCAGTCGGTTTCGGTCGCCGATGCGAACCGCAAGGCGGGT
CTGGCGGAAATGCAGGCAGCCCAGCACAATGTCGATCGCTTCGAGGCGCTTGAAAAATTCAAGACCATCGTCGCGCCGTT
CGACGGGGTGGTCACGTCACGTGACATCAATGTCGGTGACTATGTCAGCAGCGGGGCGGGGGAGCATGGCAGCAATGGCG
ATGCCAGCCAGCTCTTCGTCGTGTCGGATATGCACAAGATGCGTCTGTTCGTGTCGGTGCCCGAGACCTTCTCTTATATT
CTCAAGCCTGGGATGACGGCGGAAGTTACCGTGCCGCAGTTCCCGAACCAGGCTTTCAAGGCTGACTTCCTGACGATCGC
ACGGGGCTACGACCCCAACACCCGCACGGCGGTAACGGAATTCACCATCGACAACGACAAGCACGTGCTGTGGCCAGGCA
CGTTCGCTTCGGTCAAGATGACGGCGCCTTCGACGCCGGGAGTGTTCCAGATCCCGACTGCTGCCCTGGTCTTCCAGGAA
AAGGGCATGCAGGTTGCGGTGCTGGATGCGAACGATGTCGTCCATTATCGCAACATCGAGGTGGGGCGCATGGCCGATAC
CGAGACGGATGTGGTTTCGGGTATCACGGCCACCGATCGGATCATCAACAACCCTCCGGCCGATCTGCTGGAGGGGCAGA
AGGTGCATGTGGTCCAGCCGGCCAAGGGGTATGACCAGGCAAGCGAGGAAATCGAGGGATGA

Upstream 100 bases:

>100_bases
TCGGCGGCCTGATCGTGGCCACAATTTCCACCCTTCTGTTTGTTCCTTGTGTTTACGCGATCATCTATAACCGCTCGTCG
AGCCGGAAGGAGACCGTCTG

Downstream 100 bases:

>100_bases
TCGTGCGATCGCTGCGCCGGACTGTCATGTCCGGGGGGGCGATGCTGTCGCTGGCGGCGTTGTCCGCCTGCGACCTGGCG
CCCACCTATCACCCACCCAC

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MASLSRNTVLATGVCAVALLVGYQVVTRIHAVTELRAETLSNALPDVAVVHAKPSPKDVTLTLPGNIDAWYQAPIFPQAS
GYVKMWYKDYGAEVKTGDVLAEINAPSLDAQYAQAKADLAAAEAKYNLAVVSADRWHAMAKSQAVSGQSVSVADANRKAG
LAEMQAAQHNVDRFEALEKFKTIVAPFDGVVTSRDINVGDYVSSGAGEHGSNGDASQLFVVSDMHKMRLFVSVPETFSYI
LKPGMTAEVTVPQFPNQAFKADFLTIARGYDPNTRTAVTEFTIDNDKHVLWPGTFASVKMTAPSTPGVFQIPTAALVFQE
KGMQVAVLDANDVVHYRNIEVGRMADTETDVVSGITATDRIINNPPADLLEGQKVHVVQPAKGYDQASEEIEG

Sequences:

>Translated_393_residues
MASLSRNTVLATGVCAVALLVGYQVVTRIHAVTELRAETLSNALPDVAVVHAKPSPKDVTLTLPGNIDAWYQAPIFPQAS
GYVKMWYKDYGAEVKTGDVLAEINAPSLDAQYAQAKADLAAAEAKYNLAVVSADRWHAMAKSQAVSGQSVSVADANRKAG
LAEMQAAQHNVDRFEALEKFKTIVAPFDGVVTSRDINVGDYVSSGAGEHGSNGDASQLFVVSDMHKMRLFVSVPETFSYI
LKPGMTAEVTVPQFPNQAFKADFLTIARGYDPNTRTAVTEFTIDNDKHVLWPGTFASVKMTAPSTPGVFQIPTAALVFQE
KGMQVAVLDANDVVHYRNIEVGRMADTETDVVSGITATDRIINNPPADLLEGQKVHVVQPAKGYDQASEEIEG
>Mature_392_residues
ASLSRNTVLATGVCAVALLVGYQVVTRIHAVTELRAETLSNALPDVAVVHAKPSPKDVTLTLPGNIDAWYQAPIFPQASG
YVKMWYKDYGAEVKTGDVLAEINAPSLDAQYAQAKADLAAAEAKYNLAVVSADRWHAMAKSQAVSGQSVSVADANRKAGL
AEMQAAQHNVDRFEALEKFKTIVAPFDGVVTSRDINVGDYVSSGAGEHGSNGDASQLFVVSDMHKMRLFVSVPETFSYIL
KPGMTAEVTVPQFPNQAFKADFLTIARGYDPNTRTAVTEFTIDNDKHVLWPGTFASVKMTAPSTPGVFQIPTAALVFQEK
GMQVAVLDANDVVHYRNIEVGRMADTETDVVSGITATDRIINNPPADLLEGQKVHVVQPAKGYDQASEEIEG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=332, Percent_Identity=27.1084337349398, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789929, Length=351, Percent_Identity=24.2165242165242, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786668, Length=369, Percent_Identity=24.390243902439, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786787, Length=309, Percent_Identity=21.0355987055016, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081796, Length=349, Percent_Identity=24.0687679083095, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42229; Mature: 42098

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00079 MULTICOPPER_OXIDASE1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLSRNTVLATGVCAVALLVGYQVVTRIHAVTELRAETLSNALPDVAVVHAKPSPKDVT
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEE
LTLPGNIDAWYQAPIFPQASGYVKMWYKDYGAEVKTGDVLAEINAPSLDAQYAQAKADLA
EEECCCCCCEEECCCCCCCCCEEEEEEECCCCCEECCCEEEECCCCCCCHHHHHHHHHHH
AAEAKYNLAVVSADRWHAMAKSQAVSGQSVSVADANRKAGLAEMQAAQHNVDRFEALEKF
HHCCEEEEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHH
KTIVAPFDGVVTSRDINVGDYVSSGAGEHGSNGDASQLFVVSDMHKMRLFVSVPETFSYI
HHHHCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHH
LKPGMTAEVTVPQFPNQAFKADFLTIARGYDPNTRTAVTEFTIDNDKHVLWPGTFASVKM
HCCCCEEEEECCCCCCHHHHHCEEEEECCCCCCCCEEEEEEEECCCCEEECCCCEEEEEE
TAPSTPGVFQIPTAALVFQEKGMQVAVLDANDVVHYRNIEVGRMADTETDVVSGITATDR
ECCCCCCEEECCCEEEEEECCCCEEEEEECCCEEEEECCEECCCCCCHHHHHCCCCHHHH
IINNPPADLLEGQKVHVVQPAKGYDQASEEIEG
HHCCCCHHHHCCCEEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure 
ASLSRNTVLATGVCAVALLVGYQVVTRIHAVTELRAETLSNALPDVAVVHAKPSPKDVT
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEE
LTLPGNIDAWYQAPIFPQASGYVKMWYKDYGAEVKTGDVLAEINAPSLDAQYAQAKADLA
EEECCCCCCEEECCCCCCCCCEEEEEEECCCCCEECCCEEEECCCCCCCHHHHHHHHHHH
AAEAKYNLAVVSADRWHAMAKSQAVSGQSVSVADANRKAGLAEMQAAQHNVDRFEALEKF
HHCCEEEEEEEECHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHH
KTIVAPFDGVVTSRDINVGDYVSSGAGEHGSNGDASQLFVVSDMHKMRLFVSVPETFSYI
HHHHCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHH
LKPGMTAEVTVPQFPNQAFKADFLTIARGYDPNTRTAVTEFTIDNDKHVLWPGTFASVKM
HCCCCEEEEECCCCCCHHHHHCEEEEECCCCCCCCEEEEEEEECCCCEEECCCCEEEEEE
TAPSTPGVFQIPTAALVFQEKGMQVAVLDANDVVHYRNIEVGRMADTETDVVSGITATDR
ECCCCCCEEECCCEEEEEECCCCEEEEEECCCEEEEECCEECCCCCCHHHHHCCCCHHHH
IINNPPADLLEGQKVHVVQPAKGYDQASEEIEG
HHCCCCHHHHCCCEEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]