Click here to switch to the map view.

The map label for this gene is tppB [H]

Identifier: 162149569

GI number: 162149569

Start: 3891346

End: 3892863

Strand: Direct

Name: tppB [H]

Synonym: GDI_3808

Alternate gene names: 162149569

Gene position: 3891346-3892863 (Clockwise)

Preceding gene: 162149568

Following gene: 162149572

Centisome position: 98.66

GC content: 66.21

Gene sequence:

>1518_bases
ATGTCGTCAAGGACGCGGCACGGCACCGCGGCGGCGGGACGGTACGGACTGACGGCGGCCTTGATGCTGGAGGCCGCCGA
GCGGTTCAGCTTCTACGGCATGCTCAGCATCCTTCTGGTCTACCTGCTGGATGTCCGCTCGCTCTCGGCACCGCAGGCCA
ATCTGTTCGTCGGCAGCTTCAACGCGCTGTCTCTGGTCAGCACGCTGCTGGGTGGCCGTCTGGGCGATGCTGTGCTGGGC
CCGGCGCGGACGGTCCTGTGCGGCTGTCTGATCCAGTGCGCGGCCCTGGGTCTGCTGGGTCTTTCGGGCACATGGCCGGC
GGTCTTCCTGCCGGCCGCAGCCGTCATCGCGGTGACCAATGGCCTGACGCGGACGAACATGGCGACGCTAGTCCTGCGGC
ATGCGGGCAGGGGGCAGTCCGTCGACGGGCTGTATACGCTATATGCCTTCGCCGTGAATCTGGGGGCCATGTTCGCGTTC
CTGCTCGTGCCCTGGATCGGCAAGCGCCACGGCTATGCGATTGCCTTCGGAACCTGCGCCGTGAGCCTGCTCCTGGGCAT
CGCGACGGTCCTTTTGAACGGGCGGGGATTGGTTGGCGGGGGGGCGGACGGCAAGGAATACGCCACCGATGCAGCGTGGG
CGGGCGGACGGACCATCTTGCGCGCCCTGGCCGAAATCGGCGGTGCGGTGCTGTTCTACTGGGTCGTCCTGAATTTTCCG
GCCGGTGGGCGCTGGGTCTTCTGGATCGTCATCGCCGCCATTCCGCTGTTCTGGGCCGGGCTGTGGCGCAGCGCGGCGGC
GGCGGAGCGTCCGGGCATTGCGATCTGCCTGATCCTGGTTGCGGAGGCGATGTTTTACGGCGTCTTCGACGAACAGACGA
CGTCGACCTTCGTCCTGTACGCGCTGCATGATCTGAATCGCGATTTCAGTGTTGCCGGGTTCACGCTCTTCCGGCTCGAC
GCGCCGCAGATCGTCGCCATCAATGCCGGACTGACCATGCTGATGGGGCCGCCGTTCGTCGGGCTTTACCGTGCGCTGGA
CAGGACGTTCGGCACGATCGCGCTCTCGACGAAATATGCGTGCGGGTCGGTCTTCATCGTCGTCTGCTTTCTGATCCTGT
CTGTCGACACGGCCGGTCCGGCATCGGGGCTGCGCGCTCCGTGGGGCATGTTCGGGGCCTATGCCGCGGTTTCGGTGGCG
GGGCTGGTCATGAACGGGCTGGGCCTGTCGGTCGTCACAACCTACCTGCCGTCGCGCGTGCGCAACATGTCCGTTGCCGT
CTATTACATCTCGACCGGTCTGGCGATGTACGGCGGCAGCGTGCTGGCGAACGCGATGGGCATCCGTCGTCTGGGGGCCT
CGGTATCCGTTGCGGAGAGCCTGGTCGCGTTCCATGCTCTTTTCCGGGGTTTCACGCTGCTGGCCGGCGCGGGTACGGCG
GTCATCATCCTCGTGCTGCCGGCCGTGCGGATGATGGAAAGACGCTTCGGTACTTCGCGTCCCTCACGGCCGGCGTGA

Upstream 100 bases:

>100_bases
GGCATGGGCCTTTTCGGCTATCCGATCTCGGGGGATTCTCCGACCTTATTCATCGGCGCGCCCCGTCAGTTCTTTGGCTC
CGTGCGCGCGTCCTTCTGAC

Downstream 100 bases:

>100_bases
ACGCGCACGGTGGCCGGGTGGCCGCCGGCTGCCTATTTGGTCGCGCCGGGGGTGTGGCGCGGCTGTCCTCCTGCGGTGGG
GGGCTCCCTGGGGTCCTTTC

Product: tripeptide permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSSRTRHGTAAAGRYGLTAALMLEAAERFSFYGMLSILLVYLLDVRSLSAPQANLFVGSFNALSLVSTLLGGRLGDAVLG
PARTVLCGCLIQCAALGLLGLSGTWPAVFLPAAAVIAVTNGLTRTNMATLVLRHAGRGQSVDGLYTLYAFAVNLGAMFAF
LLVPWIGKRHGYAIAFGTCAVSLLLGIATVLLNGRGLVGGGADGKEYATDAAWAGGRTILRALAEIGGAVLFYWVVLNFP
AGGRWVFWIVIAAIPLFWAGLWRSAAAAERPGIAICLILVAEAMFYGVFDEQTTSTFVLYALHDLNRDFSVAGFTLFRLD
APQIVAINAGLTMLMGPPFVGLYRALDRTFGTIALSTKYACGSVFIVVCFLILSVDTAGPASGLRAPWGMFGAYAAVSVA
GLVMNGLGLSVVTTYLPSRVRNMSVAVYYISTGLAMYGGSVLANAMGIRRLGASVSVAESLVAFHALFRGFTLLAGAGTA
VIILVLPAVRMMERRFGTSRPSRPA

Sequences:

>Translated_505_residues
MSSRTRHGTAAAGRYGLTAALMLEAAERFSFYGMLSILLVYLLDVRSLSAPQANLFVGSFNALSLVSTLLGGRLGDAVLG
PARTVLCGCLIQCAALGLLGLSGTWPAVFLPAAAVIAVTNGLTRTNMATLVLRHAGRGQSVDGLYTLYAFAVNLGAMFAF
LLVPWIGKRHGYAIAFGTCAVSLLLGIATVLLNGRGLVGGGADGKEYATDAAWAGGRTILRALAEIGGAVLFYWVVLNFP
AGGRWVFWIVIAAIPLFWAGLWRSAAAAERPGIAICLILVAEAMFYGVFDEQTTSTFVLYALHDLNRDFSVAGFTLFRLD
APQIVAINAGLTMLMGPPFVGLYRALDRTFGTIALSTKYACGSVFIVVCFLILSVDTAGPASGLRAPWGMFGAYAAVSVA
GLVMNGLGLSVVTTYLPSRVRNMSVAVYYISTGLAMYGGSVLANAMGIRRLGASVSVAESLVAFHALFRGFTLLAGAGTA
VIILVLPAVRMMERRFGTSRPSRPA
>Mature_504_residues
SSRTRHGTAAAGRYGLTAALMLEAAERFSFYGMLSILLVYLLDVRSLSAPQANLFVGSFNALSLVSTLLGGRLGDAVLGP
ARTVLCGCLIQCAALGLLGLSGTWPAVFLPAAAVIAVTNGLTRTNMATLVLRHAGRGQSVDGLYTLYAFAVNLGAMFAFL
LVPWIGKRHGYAIAFGTCAVSLLLGIATVLLNGRGLVGGGADGKEYATDAAWAGGRTILRALAEIGGAVLFYWVVLNFPA
GGRWVFWIVIAAIPLFWAGLWRSAAAAERPGIAICLILVAEAMFYGVFDEQTTSTFVLYALHDLNRDFSVAGFTLFRLDA
PQIVAINAGLTMLMGPPFVGLYRALDRTFGTIALSTKYACGSVFIVVCFLILSVDTAGPASGLRAPWGMFGAYAAVSVAG
LVMNGLGLSVVTTYLPSRVRNMSVAVYYISTGLAMYGGSVLANAMGIRRLGASVSVAESLVAFHALFRGFTLLAGAGTAV
IILVLPAVRMMERRFGTSRPSRPA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=481, Percent_Identity=25.3638253638254, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789911, Length=504, Percent_Identity=23.015873015873, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786927, Length=505, Percent_Identity=23.5643564356436, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71987453, Length=343, Percent_Identity=26.2390670553936, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53047; Mature: 52916

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRTRHGTAAAGRYGLTAALMLEAAERFSFYGMLSILLVYLLDVRSLSAPQANLFVGSF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
NALSLVSTLLGGRLGDAVLGPARTVLCGCLIQCAALGLLGLSGTWPAVFLPAAAVIAVTN
HHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GLTRTNMATLVLRHAGRGQSVDGLYTLYAFAVNLGAMFAFLLVPWIGKRHGYAIAFGTCA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHH
VSLLLGIATVLLNGRGLVGGGADGKEYATDAAWAGGRTILRALAEIGGAVLFYWVVLNFP
HHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
AGGRWVFWIVIAAIPLFWAGLWRSAAAAERPGIAICLILVAEAMFYGVFDEQTTSTFVLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
ALHDLNRDFSVAGFTLFRLDAPQIVAINAGLTMLMGPPFVGLYRALDRTFGTIALSTKYA
EHHHCCCCCEECCEEEEEECCCCEEEEECCCCEEECCCHHHHHHHHHHHHCEEEEECCCC
CGSVFIVVCFLILSVDTAGPASGLRAPWGMFGAYAAVSVAGLVMNGLGLSVVTTYLPSRV
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RNMSVAVYYISTGLAMYGGSVLANAMGIRRLGASVSVAESLVAFHALFRGFTLLAGAGTA
CCCEEEEEEEHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
VIILVLPAVRMMERRFGTSRPSRPA
HHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSRTRHGTAAAGRYGLTAALMLEAAERFSFYGMLSILLVYLLDVRSLSAPQANLFVGSF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
NALSLVSTLLGGRLGDAVLGPARTVLCGCLIQCAALGLLGLSGTWPAVFLPAAAVIAVTN
HHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
GLTRTNMATLVLRHAGRGQSVDGLYTLYAFAVNLGAMFAFLLVPWIGKRHGYAIAFGTCA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHH
VSLLLGIATVLLNGRGLVGGGADGKEYATDAAWAGGRTILRALAEIGGAVLFYWVVLNFP
HHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
AGGRWVFWIVIAAIPLFWAGLWRSAAAAERPGIAICLILVAEAMFYGVFDEQTTSTFVLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
ALHDLNRDFSVAGFTLFRLDAPQIVAINAGLTMLMGPPFVGLYRALDRTFGTIALSTKYA
EHHHCCCCCEECCEEEEEECCCCEEEEECCCCEEECCCHHHHHHHHHHHHCEEEEECCCC
CGSVFIVVCFLILSVDTAGPASGLRAPWGMFGAYAAVSVAGLVMNGLGLSVVTTYLPSRV
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RNMSVAVYYISTGLAMYGGSVLANAMGIRRLGASVSVAESLVAFHALFRGFTLLAGAGTA
CCCEEEEEEEHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
VIILVLPAVRMMERRFGTSRPSRPA
HHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA