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The map label for this gene is ntrY [H]

Identifier: 162149487

GI number: 162149487

Start: 3808699

End: 3809964

Strand: Direct

Name: ntrY [H]

Synonym: GDI_3725

Alternate gene names: 162149487

Gene position: 3808699-3809964 (Clockwise)

Preceding gene: 162149486

Following gene: 162149488

Centisome position: 96.57

GC content: 75.75

Gene sequence:

>1266_bases
ATGACGGGTGCGGCGCGCGGGCGCGCGGGCAGGCGGATTCCGGGGATCGGCCCAGCGGCGCTGGGGCTGGTGGGCATCGC
GGCGGGCGGGGCGCTGGCGGTGGTGTGCCTGCATCACCGGTTCTATGCCGCGTCGATGGTCGCCCTGGCGGGCGCGCTGG
TGCAGGGCGCGTTCGTGCTGGGGCGGATGGCGCGGCTGGAACAGCGCCTGGCCGAGCGCGCGGTGCCGGTGCGCGTGGCC
CCGCCGCGCGTGGACCAGGCGGTGGTGCTACGCGCCATGCTGGACCATGCCCCGGTGCCCCTGCTGGGCGTGACGCATGA
CGGGGTGCTGGTGGCGTCGAACCGCGCGGCGCGGCGGCTGTTCGGGACCGACGACCGGGTGCTGGACCCGCCGGCCGCCC
TGATGGCGGGGCTGGCGCGGCTGAAGGATGGCGGGCGGCTGGTGGTGCGGCTGGACCGGCCCGGCGGGGGCGATGCCGGC
GGGGCGGGGAACGGGCGGCACTACGCGCTGTCGGTGGCGCTGGGCAGCCTGCACGGCAGGTACGCCCGGCTGGTGGCGCT
GACGGATATCGAGGCCGAGCTGAATGCCGGCGAGGCGACGGCCCTGCGCGAGATCCTGCAGGTGCTGAGCCACGAAATCA
TGAATTCGCTGACGCCCGTGTCCTCTCTGGCGGAAAGCGCGCAGGAGATGCTGGCGGCGGGCGACGCGGCGGCGATGCCC
GAGGCCGCGCAGGCGCTGGCCACCATCCTGCGCCGGGTCCAGGGGCTGGACCGCTTCGTGCAGGGGTACCGCCACCTGGC
CCGCCTGCCGGCGGTGGCGCCGCGCCAGATGTCGGTGGCGGCGATGCTGCGCGATGCCGGGCGGCTGTTCGCCAGCCGGT
GGGACGGGCAGGGCGTGGCCTTGCGGCTGGACGTGCCGGTGCCCGACATCGTGGCGTGGCTGGACGGCGACCTGCTGGTG
CAGGCGCTGATCGCGCTGATGACCAACGGCGCGCAGGCGGCCCTGGCGGGTCCGCGCCGCCCGGCCTGGGTGGCGCTGTG
GGCCCGCGCGGACGCCGATCACGTGACGATCGGCGTCGGCGACAGCGGCGCGGGCGTGGCGCCGGACCAGGCGGCGCTGA
TCTTCCGGCCGTTCTTTTCATTGCGCGAGGGGGGGACCGGCATCGGCCTCAGCGTCGCGCGGCAGATCGTGCAGGACCAT
GGCGGCAGCCTGGTGCTGGCGCCGCCCGCCGAGGATGCGGGGGCCACTTTCCTGATCCGGATCTGA

Upstream 100 bases:

>100_bases
CGCCGCCATGGCTTCAATGTCAGCCACGCGGCGCGCGAACTGGGCCTGACGCGCCCGGCCCTGTACCGGCGCATGGCCCG
CCACGGGCTGTGACGCGGCG

Downstream 100 bases:

>100_bases
GGGTTGGAAAGTTCTACCGCGATAGCTTCACTTTTTCCGGATCGGCTTTCCGCGTCCCTGTCCGTGCCGTCCGGGTTTCT
TCTTGACTCGGGATTAAAAA

Product: two-component system, sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTGAARGRAGRRIPGIGPAALGLVGIAAGGALAVVCLHHRFYAASMVALAGALVQGAFVLGRMARLEQRLAERAVPVRVA
PPRVDQAVVLRAMLDHAPVPLLGVTHDGVLVASNRAARRLFGTDDRVLDPPAALMAGLARLKDGGRLVVRLDRPGGGDAG
GAGNGRHYALSVALGSLHGRYARLVALTDIEAELNAGEATALREILQVLSHEIMNSLTPVSSLAESAQEMLAAGDAAAMP
EAAQALATILRRVQGLDRFVQGYRHLARLPAVAPRQMSVAAMLRDAGRLFASRWDGQGVALRLDVPVPDIVAWLDGDLLV
QALIALMTNGAQAALAGPRRPAWVALWARADADHVTIGVGDSGAGVAPDQAALIFRPFFSLREGGTGIGLSVARQIVQDH
GGSLVLAPPAEDAGATFLIRI

Sequences:

>Translated_421_residues
MTGAARGRAGRRIPGIGPAALGLVGIAAGGALAVVCLHHRFYAASMVALAGALVQGAFVLGRMARLEQRLAERAVPVRVA
PPRVDQAVVLRAMLDHAPVPLLGVTHDGVLVASNRAARRLFGTDDRVLDPPAALMAGLARLKDGGRLVVRLDRPGGGDAG
GAGNGRHYALSVALGSLHGRYARLVALTDIEAELNAGEATALREILQVLSHEIMNSLTPVSSLAESAQEMLAAGDAAAMP
EAAQALATILRRVQGLDRFVQGYRHLARLPAVAPRQMSVAAMLRDAGRLFASRWDGQGVALRLDVPVPDIVAWLDGDLLV
QALIALMTNGAQAALAGPRRPAWVALWARADADHVTIGVGDSGAGVAPDQAALIFRPFFSLREGGTGIGLSVARQIVQDH
GGSLVLAPPAEDAGATFLIRI
>Mature_420_residues
TGAARGRAGRRIPGIGPAALGLVGIAAGGALAVVCLHHRFYAASMVALAGALVQGAFVLGRMARLEQRLAERAVPVRVAP
PRVDQAVVLRAMLDHAPVPLLGVTHDGVLVASNRAARRLFGTDDRVLDPPAALMAGLARLKDGGRLVVRLDRPGGGDAGG
AGNGRHYALSVALGSLHGRYARLVALTDIEAELNAGEATALREILQVLSHEIMNSLTPVSSLAESAQEMLAAGDAAAMPE
AAQALATILRRVQGLDRFVQGYRHLARLPAVAPRQMSVAAMLRDAGRLFASRWDGQGVALRLDVPVPDIVAWLDGDLLVQ
ALIALMTNGAQAALAGPRRPAWVALWARADADHVTIGVGDSGAGVAPDQAALIFRPFFSLREGGTGIGLSVARQIVQDHG
GSLVLAPPAEDAGATFLIRI

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=30.0469483568075, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=274, Percent_Identity=24.0875912408759, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43690; Mature: 43559

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAARGRAGRRIPGIGPAALGLVGIAAGGALAVVCLHHRFYAASMVALAGALVQGAFVL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRMARLEQRLAERAVPVRVAPPRVDQAVVLRAMLDHAPVPLLGVTHDGVLVASNRAARRL
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHH
FGTDDRVLDPPAALMAGLARLKDGGRLVVRLDRPGGGDAGGAGNGRHYALSVALGSLHGR
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHCCC
YARLVALTDIEAELNAGEATALREILQVLSHEIMNSLTPVSSLAESAQEMLAAGDAAAMP
CEEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHCCC
EAAQALATILRRVQGLDRFVQGYRHLARLPAVAPRQMSVAAMLRDAGRLFASRWDGQGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
LRLDVPVPDIVAWLDGDLLVQALIALMTNGAQAALAGPRRPAWVALWARADADHVTIGVG
EEECCCCHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEECCCCEEEEEEC
DSGAGVAPDQAALIFRPFFSLREGGTGIGLSVARQIVQDHGGSLVLAPPAEDAGATFLIR
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEE
I
C
>Mature Secondary Structure 
TGAARGRAGRRIPGIGPAALGLVGIAAGGALAVVCLHHRFYAASMVALAGALVQGAFVL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRMARLEQRLAERAVPVRVAPPRVDQAVVLRAMLDHAPVPLLGVTHDGVLVASNRAARRL
HHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEECCHHHHHH
FGTDDRVLDPPAALMAGLARLKDGGRLVVRLDRPGGGDAGGAGNGRHYALSVALGSLHGR
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHCCC
YARLVALTDIEAELNAGEATALREILQVLSHEIMNSLTPVSSLAESAQEMLAAGDAAAMP
CEEEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHCCC
EAAQALATILRRVQGLDRFVQGYRHLARLPAVAPRQMSVAAMLRDAGRLFASRWDGQGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEE
LRLDVPVPDIVAWLDGDLLVQALIALMTNGAQAALAGPRRPAWVALWARADADHVTIGVG
EEECCCCHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEECCCCEEEEEEC
DSGAGVAPDQAALIFRPFFSLREGGTGIGLSVARQIVQDHGGSLVLAPPAEDAGATFLIR
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEE
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]