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The map label for this gene is zraR [H]

Identifier: 162149486

GI number: 162149486

Start: 3807351

End: 3808691

Strand: Direct

Name: zraR [H]

Synonym: GDI_3724

Alternate gene names: 162149486

Gene position: 3807351-3808691 (Clockwise)

Preceding gene: 162149478

Following gene: 162149487

Centisome position: 96.53

GC content: 76.58

Gene sequence:

>1341_bases
ATGTCCCAAGCGCCGTCAAGCCCCATGGAGCCCGCAGTCGATTCGACCGCCGGTCAGGACCCCGAGGGCGCCTGCATCCT
GTTCGTCGACGACGATGCCGATATCCGCCAGGCGACGGCGCTGCTGCTGCGCCGCCGGGGGTTCGCGGTGGTCGGCGCGG
CGGACCCCGGCGAGGCGCTGAGCGTGCTGGCGGCGACGGCGGTGTCGGTGGTGCTGCTGGACCTGAACTATACGCGCGGC
GCCACCACCGGGGCCGAGGGGCTGGAGTGCCTGCGGGCGCTGCTGGCGCATGATCCGGGCCTGCCGGTGGTGGTGGTGAC
GGGCCATAGCGGGGTGGCGATCGCGGTGGCGGCGATGCGCGCGGGGGCGGCGGATTTCGTCATGAAGCCGTGGAAGAACG
ACCGGCTGGTGGCGACGATCGAGGATGCGCTGGCCACGCATCGCCGCCGCCTGGCCGCGCGCCAGCCCGTGGGGGCCGGG
GGACCGGCGGACGGGGCGGCCGCCCCGGCCGATGACGGGATGATGATCGCCGGCTGCGCGCAGACGCGCGACGTGCTGGA
GCGTGCCGACCGGGTGGCGCCGACCCAGGCCGGCGTGCTGCTGACCGGCCCGGCGGGGGTGGGCAAGACCGCGCTGGCGC
GGCGTATCCATCGCCTGTCGGCGCAGCGGGCCGGGCGGCTGCTGGTGCTGGACCCCCGGCTGGGCGAGGACACGGTGGCG
GTGCGGCTGGCGGGCGCGGACGCGCGCGACACGCTGCTGGTCGAGGAGATCGGCGACTGGTCGCCCGCCCTGCAGGACCG
GCTGCTGGCGCGGGTGCAGGCGGGCGGCGGGGCGCGCCTGCTGGCCACGGCGCGCGAGGGCGGGGCGGCGCTGCGCGCGT
CGGTGATGCCGGACCTGCTCTGCCGCCTGGATGTCGTGACCATCGCGCTGCCGCCGCTGGCGGCCCGGGGCGAGGAGATC
GCGGTGCTGGCCCGGCATTTCCTGCGTCTGTTCGCCCTGCGCCACGGAGTGGCGGACCGTACCCTGTCGCCCGAGGCCGA
GGAGGCGCTGGCGGCGCGGCCCTGGCCGGACAATGTCCGCGCGCTGCGCCAGGCGATGGAGCGCGCGACGGTCATGGCGC
GGGACGCGGTGCTGGGCGTGGCCGATGTCGCGGGGCCCGGGCCGGACGCGGAGGGGACGGAGGCCGGGACGCCGGATGCC
GCGCCGACGCTGGCGCGTTCCGAAAAGGCGATGATCGAGGCGGCGCTGCGCCGCCATGGCTTCAATGTCAGCCACGCGGC
GCGCGAACTGGGCCTGACGCGCCCGGCCCTGTACCGGCGCATGGCCCGCCACGGGCTGTGA

Upstream 100 bases:

>100_bases
AGGCTTGCGGAAGCGTTTTTTATCTATTTGAATAATAACGATTTTATCGAGTGTGTCCGAGGCTGGTGTCCGCCAGCGAA
CAGACTGTCCGGATCCGAAC

Downstream 100 bases:

>100_bases
CGCGGCGATGACGGGTGCGGCGCGCGGGCGCGCGGGCAGGCGGATTCCGGGGATCGGCCCAGCGGCGCTGGGGCTGGTGG
GCATCGCGGCGGGCGGGGCG

Product: two-component system, response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSQAPSSPMEPAVDSTAGQDPEGACILFVDDDADIRQATALLLRRRGFAVVGAADPGEALSVLAATAVSVVLLDLNYTRG
ATTGAEGLECLRALLAHDPGLPVVVVTGHSGVAIAVAAMRAGAADFVMKPWKNDRLVATIEDALATHRRRLAARQPVGAG
GPADGAAAPADDGMMIAGCAQTRDVLERADRVAPTQAGVLLTGPAGVGKTALARRIHRLSAQRAGRLLVLDPRLGEDTVA
VRLAGADARDTLLVEEIGDWSPALQDRLLARVQAGGGARLLATAREGGAALRASVMPDLLCRLDVVTIALPPLAARGEEI
AVLARHFLRLFALRHGVADRTLSPEAEEALAARPWPDNVRALRQAMERATVMARDAVLGVADVAGPGPDAEGTEAGTPDA
APTLARSEKAMIEAALRRHGFNVSHAARELGLTRPALYRRMARHGL

Sequences:

>Translated_446_residues
MSQAPSSPMEPAVDSTAGQDPEGACILFVDDDADIRQATALLLRRRGFAVVGAADPGEALSVLAATAVSVVLLDLNYTRG
ATTGAEGLECLRALLAHDPGLPVVVVTGHSGVAIAVAAMRAGAADFVMKPWKNDRLVATIEDALATHRRRLAARQPVGAG
GPADGAAAPADDGMMIAGCAQTRDVLERADRVAPTQAGVLLTGPAGVGKTALARRIHRLSAQRAGRLLVLDPRLGEDTVA
VRLAGADARDTLLVEEIGDWSPALQDRLLARVQAGGGARLLATAREGGAALRASVMPDLLCRLDVVTIALPPLAARGEEI
AVLARHFLRLFALRHGVADRTLSPEAEEALAARPWPDNVRALRQAMERATVMARDAVLGVADVAGPGPDAEGTEAGTPDA
APTLARSEKAMIEAALRRHGFNVSHAARELGLTRPALYRRMARHGL
>Mature_445_residues
SQAPSSPMEPAVDSTAGQDPEGACILFVDDDADIRQATALLLRRRGFAVVGAADPGEALSVLAATAVSVVLLDLNYTRGA
TTGAEGLECLRALLAHDPGLPVVVVTGHSGVAIAVAAMRAGAADFVMKPWKNDRLVATIEDALATHRRRLAARQPVGAGG
PADGAAAPADDGMMIAGCAQTRDVLERADRVAPTQAGVLLTGPAGVGKTALARRIHRLSAQRAGRLLVLDPRLGEDTVAV
RLAGADARDTLLVEEIGDWSPALQDRLLARVQAGGGARLLATAREGGAALRASVMPDLLCRLDVVTIALPPLAARGEEIA
VLARHFLRLFALRHGVADRTLSPEAEEALAARPWPDNVRALRQAMERATVMARDAVLGVADVAGPGPDAEGTEAGTPDAA
PTLARSEKAMIEAALRRHGFNVSHAARELGLTRPALYRRMARHGL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=460, Percent_Identity=33.9130434782609, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=27.7056277056277, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790299, Length=481, Percent_Identity=29.3139293139293, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788905, Length=460, Percent_Identity=29.1304347826087, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=28.5266457680251, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789087, Length=319, Percent_Identity=29.4670846394984, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082117, Length=325, Percent_Identity=29.5384615384615, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787583, Length=303, Percent_Identity=27.0627062706271, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082152, Length=303, Percent_Identity=28.3828382838284, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=25.705329153605, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081858, Length=322, Percent_Identity=26.7080745341615, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 46434; Mature: 46303

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAPSSPMEPAVDSTAGQDPEGACILFVDDDADIRQATALLLRRRGFAVVGAADPGEAL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHH
SVLAATAVSVVLLDLNYTRGATTGAEGLECLRALLAHDPGLPVVVVTGHSGVAIAVAAMR
HHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
AGAADFVMKPWKNDRLVATIEDALATHRRRLAARQPVGAGGPADGAAAPADDGMMIAGCA
CCCHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHH
QTRDVLERADRVAPTQAGVLLTGPAGVGKTALARRIHRLSAQRAGRLLVLDPRLGEDTVA
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEE
VRLAGADARDTLLVEEIGDWSPALQDRLLARVQAGGGARLLATAREGGAALRASVMPDLL
EEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
CRLDVVTIALPPLAARGEEIAVLARHFLRLFALRHGVADRTLSPEAEEALAARPWPDNVR
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHH
ALRQAMERATVMARDAVLGVADVAGPGPDAEGTEAGTPDAAPTLARSEKAMIEAALRRHG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
FNVSHAARELGLTRPALYRRMARHGL
CCHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SQAPSSPMEPAVDSTAGQDPEGACILFVDDDADIRQATALLLRRRGFAVVGAADPGEAL
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCHHHH
SVLAATAVSVVLLDLNYTRGATTGAEGLECLRALLAHDPGLPVVVVTGHSGVAIAVAAMR
HHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHH
AGAADFVMKPWKNDRLVATIEDALATHRRRLAARQPVGAGGPADGAAAPADDGMMIAGCA
CCCHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHH
QTRDVLERADRVAPTQAGVLLTGPAGVGKTALARRIHRLSAQRAGRLLVLDPRLGEDTVA
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEE
VRLAGADARDTLLVEEIGDWSPALQDRLLARVQAGGGARLLATAREGGAALRASVMPDLL
EEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
CRLDVVTIALPPLAARGEEIAVLARHFLRLFALRHGVADRTLSPEAEEALAARPWPDNVR
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHH
ALRQAMERATVMARDAVLGVADVAGPGPDAEGTEAGTPDAAPTLARSEKAMIEAALRRHG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
FNVSHAARELGLTRPALYRRMARHGL
CCHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]