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The map label for this gene is arsC [H]

Identifier: 162149411

GI number: 162149411

Start: 3727513

End: 3727878

Strand: Direct

Name: arsC [H]

Synonym: GDI_3649

Alternate gene names: 162149411

Gene position: 3727513-3727878 (Clockwise)

Preceding gene: 162149410

Following gene: 162149412

Centisome position: 94.51

GC content: 69.67

Gene sequence:

>366_bases
ATGTGCGTAACCATCTACCATAACCCGGCCTGCGGCACGTCGCGGACCGTGCTGGGCCTGATCCGCGATGCGGGCATCGC
GCCCACCATCATCGAATATCTGAAGACGCCGCCATCGCGTGACGAACTGGCCGGGCTGATCGCGCGCATGGGGGTGCCGG
TGCGCGACGTGCTGCGCCGCCGGGGAACGCCCCATGACGAACTGGGGCTGGATGACGCGGGGCTGAGCGACGACCGGCTG
CTCGACGCCATAATGGCGCATCCGATCCTGATCAACCGGCCGATCGTCGTGACGCCGCTGGGGGTCAGGCTGTGCCGCCC
GGCCGAGCGCGTCCTGGACATCCTGCCGCCGCGCCAGGGCGCGTGA

Upstream 100 bases:

>100_bases
CCTCTTCCTGGTCAGGGATTGCTGCGGCGGGGCGCCGGATGTGTGTGCGCCGCTGCTGGCCGACCTGGCCGCCTGCCGTC
CGGCTTCGGAGACCTGATCC

Downstream 100 bases:

>100_bases
TGCTGGCGCTTGCGATCTTTCTGGTCACGCTGATCCTCGTCATCTGGCAGCCCCGGCTTCCCGGGCAGCCGAGGGGGCTG
GGCATCGGGTGGAGCGCGCT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MCVTIYHNPACGTSRTVLGLIRDAGIAPTIIEYLKTPPSRDELAGLIARMGVPVRDVLRRRGTPHDELGLDDAGLSDDRL
LDAIMAHPILINRPIVVTPLGVRLCRPAERVLDILPPRQGA

Sequences:

>Translated_121_residues
MCVTIYHNPACGTSRTVLGLIRDAGIAPTIIEYLKTPPSRDELAGLIARMGVPVRDVLRRRGTPHDELGLDDAGLSDDRL
LDAIMAHPILINRPIVVTPLGVRLCRPAERVLDILPPRQGA
>Mature_121_residues
MCVTIYHNPACGTSRTVLGLIRDAGIAPTIIEYLKTPPSRDELAGLIARMGVPVRDVLRRRGTPHDELGLDDAGLSDDRL
LDAIMAHPILINRPIVVTPLGVRLCRPAERVLDILPPRQGA

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=117, Percent_Identity=64.1025641025641, Blast_Score=159, Evalue=4e-41,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=38.5964912280702, Blast_Score=89, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 13161; Mature: 13161

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVTIYHNPACGTSRTVLGLIRDAGIAPTIIEYLKTPPSRDELAGLIARMGVPVRDVLRR
CEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
RGTPHDELGLDDAGLSDDRLLDAIMAHPILINRPIVVTPLGVRLCRPAERVLDILPPRQG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCHHHCCHHHHHHHHCCCCCC
A
C
>Mature Secondary Structure
MCVTIYHNPACGTSRTVLGLIRDAGIAPTIIEYLKTPPSRDELAGLIARMGVPVRDVLRR
CEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHH
RGTPHDELGLDDAGLSDDRLLDAIMAHPILINRPIVVTPLGVRLCRPAERVLDILPPRQG
CCCCCCCCCCCCCCCCHHHHHHHHHHCCEECCCCEEECCCCHHHCCHHHHHHHHCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]