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The map label for this gene is rbsK [H]

Identifier: 162148933

GI number: 162148933

Start: 3249582

End: 3250532

Strand: Direct

Name: rbsK [H]

Synonym: GDI_3163

Alternate gene names: 162148933

Gene position: 3249582-3250532 (Clockwise)

Preceding gene: 162148927

Following gene: 162148934

Centisome position: 82.39

GC content: 70.45

Gene sequence:

>951_bases
ATGCCCCGACCCAAAAGTAAAAATCACCCTCTGGTTGTATTCGGTAGCATCAATATCGATATGGTCGCCCGGTTGCATCA
CTTTCCCGCGCCAGGCGAAACTTTACACGCACAGGGCACCGACCTGGGGCTTGGGGGCAAGGGCGCCAACCAGGCGGTGG
CGGTCGCGCGCCTGGGGGCGGAGGTCCTGCTGATGGGCCGGACCGGCGACGACATGTTCGCCGACTACGCCGCTACCTCC
CTGCGGCGGCGCGGCGTCGGGCCGGACGGCCTGTTCCGCTCGCCCGGCGACACGACCGGCCTGGCCATGATCTGCACCGA
CAGCGCGGGGGAAAACACCATCGTCGTCGCCGGGGGCGCCAACCTGGCGATGGATGGCGACGATGTGGCACGCCTGGTGC
CGCTGCTGACGCCGGGCGCGATCGTGCTGATGCAGTGCGAGATCCCGATGGACACCATCCTGGCCGCCGCCCGCCGGGTC
GACGCCGCCGGCGCGACCCTGATCCTGGACCCCGCCCCGGTCCCCGATGCCGGCCTGCCCGACGAATTGTTCCGTCTGGC
CACGCTGATGACCCCCAACGAAACCGAGACCGAACGCCTGACCGGACTGCGCCCCCACGACCCCGACAGCGCGCGCCAGG
CCGCGGGCCGGCTGCACCAAAAGGGGCTGCGCCGGGCCATCATCAAGCTGGGCGCGCGGGGCGTGCTGTATTCCGACGAG
TCGGGCCACGGATTCATTCCCCCTTTCCACGTCACCGCCATCGACAGCGTGGCGGCGGGCGATTGTTTCAATGGCGGGCT
GGCCGTAGCGTTGTCGCAGGGCCTGGACCTGGCCCGGGCCACGCGCTTCGCCGCCGCCTGCGGCGCGCTGGCCACCACGC
GCAAGGGCGCGGCGGACGCCGCCCCGACCCGCGAGGAAGTGGAGGGCCTGCTTTCGGCACAGCCGCGATAA

Upstream 100 bases:

>100_bases
GATTCGTAACAAAAATTTACGATGAAACACAGCAGAATTATAGTGCATTTCAATAATTAATACAACGACTTTTTCTAAAT
TTAACGAAAGCCGGATATCC

Downstream 100 bases:

>100_bases
GTATCCGACCTTTTGGCGCGACCCCGCGTTGCGTGCGGTATGATCACCCTGCCGGCCGTCCCATCGGCCGGCGATCGGGA
GGCACCATGATCGACCTGTA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPRPKSKNHPLVVFGSINIDMVARLHHFPAPGETLHAQGTDLGLGGKGANQAVAVARLGAEVLLMGRTGDDMFADYAATS
LRRRGVGPDGLFRSPGDTTGLAMICTDSAGENTIVVAGGANLAMDGDDVARLVPLLTPGAIVLMQCEIPMDTILAAARRV
DAAGATLILDPAPVPDAGLPDELFRLATLMTPNETETERLTGLRPHDPDSARQAAGRLHQKGLRRAIIKLGARGVLYSDE
SGHGFIPPFHVTAIDSVAAGDCFNGGLAVALSQGLDLARATRFAAACGALATTRKGAADAAPTREEVEGLLSAQPR

Sequences:

>Translated_316_residues
MPRPKSKNHPLVVFGSINIDMVARLHHFPAPGETLHAQGTDLGLGGKGANQAVAVARLGAEVLLMGRTGDDMFADYAATS
LRRRGVGPDGLFRSPGDTTGLAMICTDSAGENTIVVAGGANLAMDGDDVARLVPLLTPGAIVLMQCEIPMDTILAAARRV
DAAGATLILDPAPVPDAGLPDELFRLATLMTPNETETERLTGLRPHDPDSARQAAGRLHQKGLRRAIIKLGARGVLYSDE
SGHGFIPPFHVTAIDSVAAGDCFNGGLAVALSQGLDLARATRFAAACGALATTRKGAADAAPTREEVEGLLSAQPR
>Mature_315_residues
PRPKSKNHPLVVFGSINIDMVARLHHFPAPGETLHAQGTDLGLGGKGANQAVAVARLGAEVLLMGRTGDDMFADYAATSL
RRRGVGPDGLFRSPGDTTGLAMICTDSAGENTIVVAGGANLAMDGDDVARLVPLLTPGAIVLMQCEIPMDTILAAARRVD
AAGATLILDPAPVPDAGLPDELFRLATLMTPNETETERLTGLRPHDPDSARQAAGRLHQKGLRRAIIKLGARGVLYSDES
GHGFIPPFHVTAIDSVAAGDCFNGGLAVALSQGLDLARATRFAAACGALATTRKGAADAAPTREEVEGLLSAQPR

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=266, Percent_Identity=33.4586466165414, Blast_Score=137, Evalue=9e-33,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=41.1184210526316, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1788491, Length=292, Percent_Identity=28.0821917808219, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788484, Length=296, Percent_Identity=24.6621621621622, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082343, Length=317, Percent_Identity=28.391167192429, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788417, Length=314, Percent_Identity=24.5222929936306, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87081971, Length=279, Percent_Identity=26.5232974910394, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=306, Percent_Identity=36.2745098039216, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=28.7009063444109, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI20128807, Length=286, Percent_Identity=32.8671328671329, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24583886, Length=310, Percent_Identity=28.3870967741935, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32742; Mature: 32611

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPKSKNHPLVVFGSINIDMVARLHHFPAPGETLHAQGTDLGLGGKGANQAVAVARLGA
CCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHCCE
EVLLMGRTGDDMFADYAATSLRRRGVGPDGLFRSPGDTTGLAMICTDSAGENTIVVAGGA
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCC
NLAMDGDDVARLVPLLTPGAIVLMQCEIPMDTILAAARRVDAAGATLILDPAPVPDAGLP
CEEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
DELFRLATLMTPNETETERLTGLRPHDPDSARQAAGRLHQKGLRRAIIKLGARGVLYSDE
HHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
SGHGFIPPFHVTAIDSVAAGDCFNGGLAVALSQGLDLARATRFAAACGALATTRKGAADA
CCCCCCCCCEEEEHHHHHCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
APTREEVEGLLSAQPR
CCCHHHHHHHHCCCCC
>Mature Secondary Structure 
PRPKSKNHPLVVFGSINIDMVARLHHFPAPGETLHAQGTDLGLGGKGANQAVAVARLGA
CCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHCCE
EVLLMGRTGDDMFADYAATSLRRRGVGPDGLFRSPGDTTGLAMICTDSAGENTIVVAGGA
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCC
NLAMDGDDVARLVPLLTPGAIVLMQCEIPMDTILAAARRVDAAGATLILDPAPVPDAGLP
CEEECCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCH
DELFRLATLMTPNETETERLTGLRPHDPDSARQAAGRLHQKGLRRAIIKLGARGVLYSDE
HHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
SGHGFIPPFHVTAIDSVAAGDCFNGGLAVALSQGLDLARATRFAAACGALATTRKGAADA
CCCCCCCCCEEEEHHHHHCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
APTREEVEGLLSAQPR
CCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]