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The map label for this gene is drgA [H]

Identifier: 162146812

GI number: 162146812

Start: 1009922

End: 1010530

Strand: Reverse

Name: drgA [H]

Synonym: GDI_0994

Alternate gene names: 162146812

Gene position: 1010530-1009922 (Counterclockwise)

Preceding gene: 162146813

Following gene: 162146810

Centisome position: 25.62

GC content: 59.28

Gene sequence:

>609_bases
ATGATGAACGAGATTCTGGATACGATGTTTGCGCGACGGGCGACGAAGCGTTTCGACGCGCACCATACGATTCCTGATGA
AACGCTGACCGCCATTTTGCGCGCCGCGCGAACGGCACCGACTGCGTTCAATATCCAGAATTGGCGGTTCCTGGTGGTGC
GCGATCCCGCCGTCCGTGCCGCAATCAAGGCGGTGGCGTGGCACCAGCCGCAGATCGAGGAATGTTCGGCACTCGTCGTC
CTGTGCGCGGACATGCACGCCTATGCGAAGGACCCCGGACGCTACTGGAAAGACGCGCCGGAGGCTATGCGTGAGAAATA
TATCGGCATGATCACACAGTATTACGAAAACAACCCGACGATGCAGCGCGACGAGGCATTTCGCTCTGCCGGCATGGCGG
CATACGCATTGATGATGGCGGCGTCAGCGCATGGCTACGATACGTGCCCGATGGACGGGTTCGATTTCGAGCAAGTCGCG
GAGATCATCCGCCTGCCCAAGGACCATGCGCTGGTCATGTTCGTCGCGATTGGCAAGGGAACGGGCGATCTGCCTCCGCA
TGGGGGACGGATCCCGGATATCGATGTCATTGCCTTTGATCGGTTTTGA

Upstream 100 bases:

>100_bases
GTCGTGGAACTCGGGATCGAGGGGCTTGGCCGGCAGCGGCAATGCGTGGCCTGATGCGCCTCGCGCCAGCAGCGGATCTG
AATGAGGAGAGGGAGAAAGC

Downstream 100 bases:

>100_bases
TCGAGGGGATGTCGCGTAGATCCCGGCGACCAGTAATCTCGTAACAATCGATCCAAAAAAAATGGAGTGTCAGATAACTC
ATGGGGGTTCGGAGGCTTTA

Product: NAD(P)H nitroreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MMNEILDTMFARRATKRFDAHHTIPDETLTAILRAARTAPTAFNIQNWRFLVVRDPAVRAAIKAVAWHQPQIEECSALVV
LCADMHAYAKDPGRYWKDAPEAMREKYIGMITQYYENNPTMQRDEAFRSAGMAAYALMMAASAHGYDTCPMDGFDFEQVA
EIIRLPKDHALVMFVAIGKGTGDLPPHGGRIPDIDVIAFDRF

Sequences:

>Translated_202_residues
MMNEILDTMFARRATKRFDAHHTIPDETLTAILRAARTAPTAFNIQNWRFLVVRDPAVRAAIKAVAWHQPQIEECSALVV
LCADMHAYAKDPGRYWKDAPEAMREKYIGMITQYYENNPTMQRDEAFRSAGMAAYALMMAASAHGYDTCPMDGFDFEQVA
EIIRLPKDHALVMFVAIGKGTGDLPPHGGRIPDIDVIAFDRF
>Mature_202_residues
MMNEILDTMFARRATKRFDAHHTIPDETLTAILRAARTAPTAFNIQNWRFLVVRDPAVRAAIKAVAWHQPQIEECSALVV
LCADMHAYAKDPGRYWKDAPEAMREKYIGMITQYYENNPTMQRDEAFRSAGMAAYALMMAASAHGYDTCPMDGFDFEQVA
EIIRLPKDHALVMFVAIGKGTGDLPPHGGRIPDIDVIAFDRF

Specific function: Controls resistance to the herbicide Dinoseb and metronidazole. Involved in detoxification of Dinoseb via the reduction of the nitro group(s) and this process is accompanied by the formation of toxic superoxide anions [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 22766; Mature: 22766

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNEILDTMFARRATKRFDAHHTIPDETLTAILRAARTAPTAFNIQNWRFLVVRDPAVRA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCEEEEEEECHHHHH
AIKAVAWHQPQIEECSALVVLCADMHAYAKDPGRYWKDAPEAMREKYIGMITQYYENNPT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCC
MQRDEAFRSAGMAAYALMMAASAHGYDTCPMDGFDFEQVAEIIRLPKDHALVMFVAIGKG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCC
TGDLPPHGGRIPDIDVIAFDRF
CCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MMNEILDTMFARRATKRFDAHHTIPDETLTAILRAARTAPTAFNIQNWRFLVVRDPAVRA
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCEEEEEEECHHHHH
AIKAVAWHQPQIEECSALVVLCADMHAYAKDPGRYWKDAPEAMREKYIGMITQYYENNPT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCC
MQRDEAFRSAGMAAYALMMAASAHGYDTCPMDGFDFEQVAEIIRLPKDHALVMFVAIGKG
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCC
TGDLPPHGGRIPDIDVIAFDRF
CCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Fmn (Potential) [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9654132; 8905231; 9298645 [H]