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The map label for this gene is thyX [H]

Identifier: 162146690

GI number: 162146690

Start: 884789

End: 885739

Strand: Reverse

Name: thyX [H]

Synonym: GDI_0868

Alternate gene names: 162146690

Gene position: 885739-884789 (Counterclockwise)

Preceding gene: 162146695

Following gene: 162146687

Centisome position: 22.46

GC content: 68.35

Gene sequence:

>951_bases
ATGTTTTCAACGGACCAGAAATCGGAAATCGACGCCGCCCGCGCCGCCTGGGCCGAGACGCGCCGCACGGTCGTGCCGGC
GGCCGAGGAGGCGCTGTACGCGCCCGTCCCGGTGCTGGAGACCGGATTCGTGCGCCTGGTCGATTACATGGGCGGGGACG
CCGCCATCGTGCAGGGGGCCCGTGTCTCCTACGGCAAGGGCACGCGCAGCACGTCCGACGACCGGGGGCTGATCCGCTAC
CTGATGCGCAACCGGCATACCAGCCCGTTCGAGCTGGCGGTGGCCAAGTTCCATGTCCGCGCGCCCATCTTCGTGACCCG
GCAATGGTTCCGCCACCGCACCGCCAGCATCAACGAATATTCCGCGCGCTATTCGGTGCTGGAGAAGGAATTCTACTTCC
CCCGCCCCGAGGACATCGCCCGCCAGTCCGCCAGCAACAAGCAGGGGCGCGGCGAGACCCTGCCCCCCGAGGCCGCGCAG
CACGTGCTGGACCTGCTGCGCGAGGACGCGGGGCGGTGCTACGACCATTATCTGGAAATGCTGAACCAGGACGAGGCCGG
GAACGTGATCGACCCCGACCGCCCGGTGGTGGCGCGCGAACTGGCGCGCATGACCCTGCCGGTGAACGTGATGACGCAGT
TCTACTGGCAGATCAATCTGTGGAACCTGCTGCATTTCCTGCGCCTGCGGGCGGACGCGCACGCCCAGTACGAGATCCGT
GCCTATGCCGACGCGATCCTGGGCCTGGTAGAACGCTGGGTGCCGCACACCTTCGAGGCCTTCCGCGACTACATGCAGGA
AGCCGCCCTGCTGTCCGGCCCAGCGCTGCGCGCGCTGCGCGCGGTCCTGGCGGGGCAGGAGGTCGACCTTCAGGCCAGCG
GCCTGTCGAAGCGCGAGGTGAGCGAACTGGTGGCCATGCTGCCGGAAATCGGCCCCCGTCTCCGTCCCTGA

Upstream 100 bases:

>100_bases
CCCGGCGGTCGTCGCGGCGGTCGCGGCCCCCGCCGTTTCGTGTTATGCGCGCCGCTTGGCATACACCGATCGGCACAGCG
ACAGAGGCGGGGACGCAGCG

Downstream 100 bases:

>100_bases
CGGGCTATTCCGGCAGCAGGTTCGACGGGCCGCGTTCCAGCACCGTGACCGCATCGCCCACGGCGATGCGGCCGGGCCGC
ACGACGGCGGCGTTCTGGCC

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MFSTDQKSEIDAARAAWAETRRTVVPAAEEALYAPVPVLETGFVRLVDYMGGDAAIVQGARVSYGKGTRSTSDDRGLIRY
LMRNRHTSPFELAVAKFHVRAPIFVTRQWFRHRTASINEYSARYSVLEKEFYFPRPEDIARQSASNKQGRGETLPPEAAQ
HVLDLLREDAGRCYDHYLEMLNQDEAGNVIDPDRPVVARELARMTLPVNVMTQFYWQINLWNLLHFLRLRADAHAQYEIR
AYADAILGLVERWVPHTFEAFRDYMQEAALLSGPALRALRAVLAGQEVDLQASGLSKREVSELVAMLPEIGPRLRP

Sequences:

>Translated_316_residues
MFSTDQKSEIDAARAAWAETRRTVVPAAEEALYAPVPVLETGFVRLVDYMGGDAAIVQGARVSYGKGTRSTSDDRGLIRY
LMRNRHTSPFELAVAKFHVRAPIFVTRQWFRHRTASINEYSARYSVLEKEFYFPRPEDIARQSASNKQGRGETLPPEAAQ
HVLDLLREDAGRCYDHYLEMLNQDEAGNVIDPDRPVVARELARMTLPVNVMTQFYWQINLWNLLHFLRLRADAHAQYEIR
AYADAILGLVERWVPHTFEAFRDYMQEAALLSGPALRALRAVLAGQEVDLQASGLSKREVSELVAMLPEIGPRLRP
>Mature_316_residues
MFSTDQKSEIDAARAAWAETRRTVVPAAEEALYAPVPVLETGFVRLVDYMGGDAAIVQGARVSYGKGTRSTSDDRGLIRY
LMRNRHTSPFELAVAKFHVRAPIFVTRQWFRHRTASINEYSARYSVLEKEFYFPRPEDIARQSASNKQGRGETLPPEAAQ
HVLDLLREDAGRCYDHYLEMLNQDEAGNVIDPDRPVVARELARMTLPVNVMTQFYWQINLWNLLHFLRLRADAHAQYEIR
AYADAILGLVERWVPHTFEAFRDYMQEAALLSGPALRALRAVLAGQEVDLQASGLSKREVSELVAMLPEIGPRLRP

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 35916; Mature: 35916

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSTDQKSEIDAARAAWAETRRTVVPAAEEALYAPVPVLETGFVRLVDYMGGDAAIVQGA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHCCC
RVSYGKGTRSTSDDRGLIRYLMRNRHTSPFELAVAKFHVRAPIFVTRQWFRHRTASINEY
EECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
SARYSVLEKEFYFPRPEDIARQSASNKQGRGETLPPEAAQHVLDLLREDAGRCYDHYLEM
HHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNQDEAGNVIDPDRPVVARELARMTLPVNVMTQFYWQINLWNLLHFLRLRADAHAQYEIR
HCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AYADAILGLVERWVPHTFEAFRDYMQEAALLSGPALRALRAVLAGQEVDLQASGLSKREV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCCCHHHH
SELVAMLPEIGPRLRP
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFSTDQKSEIDAARAAWAETRRTVVPAAEEALYAPVPVLETGFVRLVDYMGGDAAIVQGA
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHCCC
RVSYGKGTRSTSDDRGLIRYLMRNRHTSPFELAVAKFHVRAPIFVTRQWFRHRTASINEY
EECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
SARYSVLEKEFYFPRPEDIARQSASNKQGRGETLPPEAAQHVLDLLREDAGRCYDHYLEM
HHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LNQDEAGNVIDPDRPVVARELARMTLPVNVMTQFYWQINLWNLLHFLRLRADAHAQYEIR
HCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AYADAILGLVERWVPHTFEAFRDYMQEAALLSGPALRALRAVLAGQEVDLQASGLSKREV
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHCCCCHHHH
SELVAMLPEIGPRLRP
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA