Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 162146656

GI number: 162146656

Start: 854023

End: 855078

Strand: Reverse

Name: galE [H]

Synonym: GDI_0834

Alternate gene names: 162146656

Gene position: 855078-854023 (Counterclockwise)

Preceding gene: 162146657

Following gene: 162146651

Centisome position: 21.68

GC content: 66.76

Gene sequence:

>1056_bases
ATGACGACACGATCACGCTTTCTGGTCACGGGCGGCGCGGGCTATGTCGGCAGCCATGTCGTGGCCGCGCTGTGCGATGC
GGGGCATGATGTCGTCATATTCGACAATCTACGGACCGGACATCGGGAGTCCGTCCCCGATGGCGTGCGCTTCGTCCCGG
GAGACCTGGCGGACCGGCCGCTGGTGGACAGGGTGCTGGCGGACGGCCCGTGGGACGGCGTGCTGCATTTCGCCGCGCTG
TCCCTGGTCGGCGAGAGCATGCAGCAGCCGTTCCTGTACATGGAGGCCAATGCCGGACTGGGATTTTCGCTGATCGATGC
CTGTGTCCGCCATGGCGTCAAGCGGTTCGTCTTCTCATCGACCGCCGCCCTGTTCGGACAGACCGAGGACGCCCTGATCA
CCGAGCGGACACCCATCATTCCCGGCTCGCCCTACGGCGAGAGCAAGCACATGGTGGAACGCGCGCTGGTGTGGGCCGAC
CGCATTCACGGATTGCGCAGTGCCTGCCTGCGCTATTTCAACGCGGCCGGTGCCGATCCCACCGGACGGATCGGCGAGGA
CCACCGGCCCGAAACGCACCTGATCCCCCTGGTCATCGATGCCGCTCTGGGACGACGGGGGGAACTGCAATTGTTCGGCG
ACGATTATCCGACGCCGGACGGTACCTGCATCCGCGATTACATCCACGTCACCGACCTGGCGCAGGCGCATCTGGCGGCC
CTGGACGTCATCCATGACCGCAGCGTCGTCTATAATGTCGGAAACGGGGTCGGTCATTCCAACATGGAGGTCATCCGCAG
CGTGGAACGCGTGACCGGGCGCACCGTCCCGTGGCGCCTGGCCCCGCGCCGTCCCGGCGACCCCGCGCGCCTGGTCGCCG
GAGCCGAGCGGCTGCGCGCGGAAACGTCCTGGACCCCCCGCTTCGCCAGACTGGATGACATCGTCGAGACGGCCTATCGC
TGGCGCCTGGCCCACCCGGACGGCTATCGCAGCCTGGTCGCCGCCGAGAGCCTGCTAGAGCAGATCCTGAGTAGGCGGAA
TCGCCTAATCACGTGA

Upstream 100 bases:

>100_bases
GATATCATCCGGTTCGAGGATAACTACAACCGCAGCTGATGCCTCATCTCCGAAATTCGATCGGCGGATTTCGGAGGTCG
GCAGCCTCCGGGAGAGGATC

Downstream 100 bases:

>100_bases
AGATGCGCTGAAAACAAAAATCTAGAGTGCATGATTGGGTTTACCCAATCATGCACTCTAAGAGGCCGACTAAGGCACCA
TCAGGGTCCCGCTATCCACC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTTRSRFLVTGGAGYVGSHVVAALCDAGHDVVIFDNLRTGHRESVPDGVRFVPGDLADRPLVDRVLADGPWDGVLHFAAL
SLVGESMQQPFLYMEANAGLGFSLIDACVRHGVKRFVFSSTAALFGQTEDALITERTPIIPGSPYGESKHMVERALVWAD
RIHGLRSACLRYFNAAGADPTGRIGEDHRPETHLIPLVIDAALGRRGELQLFGDDYPTPDGTCIRDYIHVTDLAQAHLAA
LDVIHDRSVVYNVGNGVGHSNMEVIRSVERVTGRTVPWRLAPRRPGDPARLVAGAERLRAETSWTPRFARLDDIVETAYR
WRLAHPDGYRSLVAAESLLEQILSRRNRLIT

Sequences:

>Translated_351_residues
MTTRSRFLVTGGAGYVGSHVVAALCDAGHDVVIFDNLRTGHRESVPDGVRFVPGDLADRPLVDRVLADGPWDGVLHFAAL
SLVGESMQQPFLYMEANAGLGFSLIDACVRHGVKRFVFSSTAALFGQTEDALITERTPIIPGSPYGESKHMVERALVWAD
RIHGLRSACLRYFNAAGADPTGRIGEDHRPETHLIPLVIDAALGRRGELQLFGDDYPTPDGTCIRDYIHVTDLAQAHLAA
LDVIHDRSVVYNVGNGVGHSNMEVIRSVERVTGRTVPWRLAPRRPGDPARLVAGAERLRAETSWTPRFARLDDIVETAYR
WRLAHPDGYRSLVAAESLLEQILSRRNRLIT
>Mature_350_residues
TTRSRFLVTGGAGYVGSHVVAALCDAGHDVVIFDNLRTGHRESVPDGVRFVPGDLADRPLVDRVLADGPWDGVLHFAALS
LVGESMQQPFLYMEANAGLGFSLIDACVRHGVKRFVFSSTAALFGQTEDALITERTPIIPGSPYGESKHMVERALVWADR
IHGLRSACLRYFNAAGADPTGRIGEDHRPETHLIPLVIDAALGRRGELQLFGDDYPTPDGTCIRDYIHVTDLAQAHLAAL
DVIHDRSVVYNVGNGVGHSNMEVIRSVERVTGRTVPWRLAPRRPGDPARLVAGAERLRAETSWTPRFARLDDIVETAYRW
RLAHPDGYRSLVAAESLLEQILSRRNRLIT

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=37.1014492753623, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=37.1014492753623, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=37.1014492753623, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI7657641, Length=351, Percent_Identity=22.7920227920228, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=23.9482200647249, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI116268111, Length=293, Percent_Identity=25.938566552901, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=41.2462908011869, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788353, Length=373, Percent_Identity=30.0268096514745, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994969, Length=361, Percent_Identity=26.5927977839335, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=33.2369942196532, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=33.0459770114943, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17539532, Length=328, Percent_Identity=23.780487804878, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=352, Percent_Identity=36.3636363636364, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=36.9186046511628, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=22.9032258064516, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38624; Mature: 38493

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRSRFLVTGGAGYVGSHVVAALCDAGHDVVIFDNLRTGHRESVPDGVRFVPGDLADRP
CCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCCCH
LVDRVLADGPWDGVLHFAALSLVGESMQQPFLYMEANAGLGFSLIDACVRHGVKRFVFSS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
TAALFGQTEDALITERTPIIPGSPYGESKHMVERALVWADRIHGLRSACLRYFNAAGADP
HHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TGRIGEDHRPETHLIPLVIDAALGRRGELQLFGDDYPTPDGTCIRDYIHVTDLAQAHLAA
CCCCCCCCCCCCEEHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LDVIHDRSVVYNVGNGVGHSNMEVIRSVERVTGRTVPWRLAPRRPGDPARLVAGAERLRA
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHH
ETSWTPRFARLDDIVETAYRWRLAHPDGYRSLVAAESLLEQILSRRNRLIT
CCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTRSRFLVTGGAGYVGSHVVAALCDAGHDVVIFDNLRTGHRESVPDGVRFVPGDLADRP
CCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCCCH
LVDRVLADGPWDGVLHFAALSLVGESMQQPFLYMEANAGLGFSLIDACVRHGVKRFVFSS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
TAALFGQTEDALITERTPIIPGSPYGESKHMVERALVWADRIHGLRSACLRYFNAAGADP
HHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TGRIGEDHRPETHLIPLVIDAALGRRGELQLFGDDYPTPDGTCIRDYIHVTDLAQAHLAA
CCCCCCCCCCCCEEHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LDVIHDRSVVYNVGNGVGHSNMEVIRSVERVTGRTVPWRLAPRRPGDPARLVAGAERLRA
HHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHH
ETSWTPRFARLDDIVETAYRWRLAHPDGYRSLVAAESLLEQILSRRNRLIT
CCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]