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The map label for this gene is yflS [H]

Identifier: 161870604

GI number: 161870604

Start: 1701220

End: 1702686

Strand: Reverse

Name: yflS [H]

Synonym: NMCC_1672

Alternate gene names: 161870604

Gene position: 1702686-1701220 (Counterclockwise)

Preceding gene: 161871035

Following gene: 161870602

Centisome position: 79.07

GC content: 50.65

Gene sequence:

>1467_bases
ATGATGAAATTGGGTTTCAAACCGATACCCCTCGCCATTGCCGCAGTATTGTGCGCCCTGGTTTTGGCACTGCCCGTACC
CGACGGGGTCAAGCCTCAGGCTTGGACGCTGCTGGCCATGTTTGTCGGTGTGATTGCCGCCATTATCGGCAAGGCCATGC
CGTTGGGCGCGCTGTCGATTATTGCCGTCGGGTTGGTCGCAGTAACCGGCGTAACCGCCGACAAACCGGGCGCGGCGATG
AGCGATGCGTTGAGTGCGTTCGCCAATCCGTTGATTTGGCTGATTGCCATCGCAGTTATGATTTCGCGCGGTTTGCTCAA
AACAGGGCTGGGGATGCGTATCGGATATTTGTTTATCGCCGTTTTTGGAAGAAAAACGCTGGGCATCGGTTACAGTCTCG
CTCTTTCCGAACTGCTGCTGGCTCCCGTTACCCCTTCCAATACCGCGCGCGGCGGCGGCATTATACATCCGATTATGCAG
TCGATTGCCGGCAGTTACGGCTCCAATCCCGCAAAAGGCACAGAAGGCAAGATGGGTAAATATTTGGCTTTGGTCAACTA
TCATTCCAATCCCATTTCGTCGGCTATGTTTATTACTGCAACTGCCCCCAACCCTTTAATCGTCAACTTGATTGCCGAAA
ATTTAGGCAGTAGTTTCCGTCTTTCTTGGGGGGCGTGGGCGTGGGCAATGGCTGTTCCCGGCGTTATCGCCTTTTTCGTT
ATGCCTTTGATTTTATATTTTTTGTATCCGCCTGAAATTAAAGAAACGCCCAATGCCGTTCAATTTGCCAAAGACCGTCT
GAGGGAGATGGGTAAAATGTCGGCAGACGAAATCATTATGGCGGTCATTTTCGGTATCTTGTTGCTGTTGTGGGCAGATG
TTCCCGCCCTTATTACCGGCAATCACGCTTTTAGTATCAACGCCACCGCCACCGCATTTATCGGATTAAGCCTGCTTTTG
CTTTCCGGTGTATTGACTTGGGACGATGTTTTGAAAGAAAAAAGTGCGTGGGATACGATTATTTGGTTTGGCGCATTGAT
TATGATGGCCGCATTTTTAAATAAACTCGGACTGATTAAATGGTTCTCCGGAGTGTTGGCGGAAAGTGTCGGCGGTTTGG
GCGTTAGCGGCACGGCTGCGGGCGTAATCCTCGTGCTTGCTTATATGTATGCGCATTATATGTTTGCCAGTACTACTGCA
CATATTACCGCTATGTTCGGCGCATTTCTCGCTGCTGCTGTTTCACTGAATGCCCCGGCGATGCCGACCGCGCTGATGAT
GGCGGCCGCATCTAACATTATGATGACCCTCACTCATTATGCGACCGGTACTTCGCCTGTGATTTTCGGTTCGGGCTACA
CCACAATGGGAGAATGGTGGAAGGCGGGTTTTATCATGAGCGTGGTCAATTTTCTGATTTTTTTCGTTATCGGCAGCATT
TGGTGGAAAGTTCTGGGGTATTGGTAA

Upstream 100 bases:

>100_bases
TATCGGAAAGACGGTGAAATATCTGAATATATCTTATAAAACAATTAGTTAAATATTATTTTTCCGATTTTTCGGGACGG
TCTTTTTTACGGAGGTCAAT

Downstream 100 bases:

>100_bases
GGGAAAAATAAAATAAATTTCCAATCTGTGTTTATTTGATTGGGCGACTATTATCGTGAAATATGCCGTCTAAAGCCTTC
AGATGGCATATTTGTGCGCT

Product: C4-dicarboxylate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFVGVIAAIIGKAMPLGALSIIAVGLVAVTGVTADKPGAAM
SDALSAFANPLIWLIAIAVMISRGLLKTGLGMRIGYLFIAVFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQ
SIAGSYGSNPAKGTEGKMGKYLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSSFRLSWGAWAWAMAVPGVIAFFV
MPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSADEIIMAVIFGILLLLWADVPALITGNHAFSINATATAFIGLSLLL
LSGVLTWDDVLKEKSAWDTIIWFGALIMMAAFLNKLGLIKWFSGVLAESVGGLGVSGTAAGVILVLAYMYAHYMFASTTA
HITAMFGAFLAAAVSLNAPAMPTALMMAAASNIMMTLTHYATGTSPVIFGSGYTTMGEWWKAGFIMSVVNFLIFFVIGSI
WWKVLGYW

Sequences:

>Translated_488_residues
MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFVGVIAAIIGKAMPLGALSIIAVGLVAVTGVTADKPGAAM
SDALSAFANPLIWLIAIAVMISRGLLKTGLGMRIGYLFIAVFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQ
SIAGSYGSNPAKGTEGKMGKYLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSSFRLSWGAWAWAMAVPGVIAFFV
MPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSADEIIMAVIFGILLLLWADVPALITGNHAFSINATATAFIGLSLLL
LSGVLTWDDVLKEKSAWDTIIWFGALIMMAAFLNKLGLIKWFSGVLAESVGGLGVSGTAAGVILVLAYMYAHYMFASTTA
HITAMFGAFLAAAVSLNAPAMPTALMMAAASNIMMTLTHYATGTSPVIFGSGYTTMGEWWKAGFIMSVVNFLIFFVIGSI
WWKVLGYW
>Mature_488_residues
MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFVGVIAAIIGKAMPLGALSIIAVGLVAVTGVTADKPGAAM
SDALSAFANPLIWLIAIAVMISRGLLKTGLGMRIGYLFIAVFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQ
SIAGSYGSNPAKGTEGKMGKYLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSSFRLSWGAWAWAMAVPGVIAFFV
MPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSADEIIMAVIFGILLLLWADVPALITGNHAFSINATATAFIGLSLLL
LSGVLTWDDVLKEKSAWDTIIWFGALIMMAAFLNKLGLIKWFSGVLAESVGGLGVSGTAAGVILVLAYMYAHYMFASTTA
HITAMFGAFLAAAVSLNAPAMPTALMMAAASNIMMTLTHYATGTSPVIFGSGYTTMGEWWKAGFIMSVVNFLIFFVIGSI
WWKVLGYW

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=467, Percent_Identity=35.3319057815846, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1789444, Length=489, Percent_Identity=33.5378323108384, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1786829, Length=486, Percent_Identity=32.0987654320988, Blast_Score=246, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 51659; Mature: 51659

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFVGVIAAIIGKAMPLGALSI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IAVGLVAVTGVTADKPGAAMSDALSAFANPLIWLIAIAVMISRGLLKTGLGMRIGYLFIA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQSIAGSYGSNPAKGTEGKMGK
HHCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
YLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSSFRLSWGAWAWAMAVPGVIAFFV
EEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHH
MPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSADEIIMAVIFGILLLLWADVPALITG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
NHAFSINATATAFIGLSLLLLSGVLTWDDVLKEKSAWDTIIWFGALIMMAAFLNKLGLIK
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFSGVLAESVGGLGVSGTAAGVILVLAYMYAHYMFASTTAHITAMFGAFLAAAVSLNAPA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MPTALMMAAASNIMMTLTHYATGTSPVIFGSGYTTMGEWWKAGFIMSVVNFLIFFVIGSI
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WWKVLGYW
HHHHHCCC
>Mature Secondary Structure
MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFVGVIAAIIGKAMPLGALSI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IAVGLVAVTGVTADKPGAAMSDALSAFANPLIWLIAIAVMISRGLLKTGLGMRIGYLFIA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQSIAGSYGSNPAKGTEGKMGK
HHCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
YLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSSFRLSWGAWAWAMAVPGVIAFFV
EEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHH
MPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSADEIIMAVIFGILLLLWADVPALITG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
NHAFSINATATAFIGLSLLLLSGVLTWDDVLKEKSAWDTIIWFGALIMMAAFLNKLGLIK
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFSGVLAESVGGLGVSGTAAGVILVLAYMYAHYMFASTTAHITAMFGAFLAAAVSLNAPA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
MPTALMMAAASNIMMTLTHYATGTSPVIFGSGYTTMGEWWKAGFIMSVVNFLIFFVIGSI
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WWKVLGYW
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]