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The map label for this gene is fmt [H]

Identifier: 161870944

GI number: 161870944

Start: 2082330

End: 2083256

Strand: Reverse

Name: fmt [H]

Synonym: NMCC_2038

Alternate gene names: 161870944

Gene position: 2083256-2082330 (Counterclockwise)

Preceding gene: 161870945

Following gene: 161870943

Centisome position: 96.74

GC content: 59.87

Gene sequence:

>927_bases
ATGAAAGTCATCTTCGCCGGCACGCCCGATTTTGCCGCCGCCGCCTTAAGAGCCGTTGCCGCCGCCGGTTTTGAAATTCC
GCTGGTGCTGACCCAGCCCGACCGTCCGAAAGGGCGCGGTATGCAACTGACTGCCCCGCCCGTCAAACAAGCCGCGCTGG
AACTCGGTTTGCGCGTCGAACAGCCCGAAAAGCTGCGCAACAACGCCGAAGCCCTGCAAATGCTCAAAGAGGTCGAGGCA
GACGTAATGGTGGTTGCCGCCTACGGTTTGATTCTGCCGCAAGACGTGTTGGATGTGCCGAAACACGGCTGCCTCAATAT
CCACGCCTCGCTGCTGCCCCGTTGGCGCGGCGCGGCGCCGATTCAGCGCGCGATTGAGGCCGGCGATGCCGAAACCGGCG
TGTGCATTATGCAGATGGATGCCGGTTTGGACACCGGTGATGTGGTCAGCGAACACCGCTACGCCATCCGACCTACCGAT
ACCGCCAACGAAGTCCACGACGCACTGATGGAAATCGGTGCGGCGGCGGTTGTTGCCGATTTGCAACAGCTTCAAAGCAA
AGGCCGTCTGAACGCGGTCAAACAGCCCAAAGAAGGTGTTACTTACGCCCAAAAACTAAGCAAAGAAGAGGCGCGTATCG
ATTGGAGCGAAAGCGCGGCGGTTATCGAACGCAAAATCCGCGCCTTCAACCCCGTGCCTGCCGCGTGGGTTGAGTATCAG
GGCAAGCCGATGAAAATCCGGCGGGCGGAAGTGGTGGCGCAACAAGGCGCGGCAGGCGAAGTGTTGTCCTGTTCGGCGGA
CGGTTTGGTCGTTGCCTGCGGCGAAAACGCGCTGAAGATTACCGAATTGCAGCCTGCCGGCGGCAAACGCATGAGCATAC
AGGCATTTGCGGCAGGTCGGACGATTGAAGTCGGAACGGTTTTGTAA

Upstream 100 bases:

>100_bases
ACATACGATTTGACCCTTTTGCCGTGCCGTCTGAACGCTGCAAAGTTTTTCAGACGGCACGGTCTTGTCCGACAATTTTA
CGCACACGCAGGAACACGCT

Downstream 100 bases:

>100_bases
CAGGCTGGAAGTCAACGTAGAGGAAAGAAGACAATGGCTGTTTTTGACGTGGTCGAGGGCGATATTACCCGATTGGCAAT
CGATGCGATTGTCAATGCCG

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEA
DVMVVAAYGLILPQDVLDVPKHGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDAGLDTGDVVSEHRYAIRPTD
TANEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPKEGVTYAQKLSKEEARIDWSESAAVIERKIRAFNPVPAAWVEYQ
GKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGKRMSIQAFAAGRTIEVGTVL

Sequences:

>Translated_308_residues
MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEA
DVMVVAAYGLILPQDVLDVPKHGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDAGLDTGDVVSEHRYAIRPTD
TANEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPKEGVTYAQKLSKEEARIDWSESAAVIERKIRAFNPVPAAWVEYQ
GKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGKRMSIQAFAAGRTIEVGTVL
>Mature_308_residues
MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEA
DVMVVAAYGLILPQDVLDVPKHGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDAGLDTGDVVSEHRYAIRPTD
TANEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPKEGVTYAQKLSKEEARIDWSESAAVIERKIRAFNPVPAAWVEYQ
GKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGKRMSIQAFAAGRTIEVGTVL

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=316, Percent_Identity=28.4810126582279, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI164663775, Length=249, Percent_Identity=34.136546184739, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI21614513, Length=242, Percent_Identity=29.3388429752066, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789683, Length=302, Percent_Identity=52.317880794702, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788589, Length=294, Percent_Identity=27.2108843537415, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI133930964, Length=258, Percent_Identity=27.5193798449612, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571984, Length=229, Percent_Identity=32.3144104803493, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45550868, Length=229, Percent_Identity=31.8777292576419, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24585660, Length=245, Percent_Identity=26.9387755102041, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 32866; Mature: 32866

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVE
CEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHCCCCC
QPEKLRNNAEALQMLKEVEADVMVVAAYGLILPQDVLDVPKHGCLNIHASLLPRWRGAAP
CHHHHHCHHHHHHHHHHHHHCEEEEEHHHHHCCHHHHHCCCCCCEEEHHHHCCCCCCCCH
IQRAIEAGDAETGVCIMQMDAGLDTGDVVSEHRYAIRPTDTANEVHDALMEIGAAAVVAD
HHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
LQQLQSKGRLNAVKQPKEGVTYAQKLSKEEARIDWSESAAVIERKIRAFNPVPAAWVEYQ
HHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHCCC
GKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGKRMSIQAFAAGR
CCCEEEHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEEECCCCCCEEEEEEEECCC
TIEVGTVL
EEEECCCC
>Mature Secondary Structure
MKVIFAGTPDFAAAALRAVAAAGFEIPLVLTQPDRPKGRGMQLTAPPVKQAALELGLRVE
CEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHCCCCC
QPEKLRNNAEALQMLKEVEADVMVVAAYGLILPQDVLDVPKHGCLNIHASLLPRWRGAAP
CHHHHHCHHHHHHHHHHHHHCEEEEEHHHHHCCHHHHHCCCCCCEEEHHHHCCCCCCCCH
IQRAIEAGDAETGVCIMQMDAGLDTGDVVSEHRYAIRPTDTANEVHDALMEIGAAAVVAD
HHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
LQQLQSKGRLNAVKQPKEGVTYAQKLSKEEARIDWSESAAVIERKIRAFNPVPAAWVEYQ
HHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHCCC
GKPMKIRRAEVVAQQGAAGEVLSCSADGLVVACGENALKITELQPAGGKRMSIQAFAAGR
CCCEEEHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEEECCCCCCEEEEEEEECCC
TIEVGTVL
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA